Neuromuscular Blocking Agents
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties
Abstract Background: Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities. This study aimed to evaluate toxicological activities and potential as antitumor and antiophidic agents contained in total extracts from fi
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/09/2018
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2. Estudo dos efeitos farmacologicos do veneno de Micrurus pyrrhocryptus sobre a junção neuromuscular e de sua neutralização pelo antiveneno especifico e comercial / Pharmacological study of Micrurus pyrrhocryptus venom on neuromuscular transmission and its neutralization by specific and commercial coral snake antivenom
A espécie Micrurus pyrrhocryptus, classificada anteriormente como subespécie da Micrurus frontalis, foi recentemente classificada como espécie plena baseada nas diferenças morfológicas. Esta serpente é especialmente encontrada no continente Sul Americano. No presente trabalho foram analisados os efeitos farmacológicos do veneno de M. pyrrhocryptus sob
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/01/2010
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3. Acurácia diagnóstica, análise da decisão e heurísticas relacionadas à decisão clínica intuitiva de usar antagonista de bloqueador neuromuscular / Diagnostic accuracy, decision analysis and heuristics related to the clinical intuitive decision of using antagonist of neuromuscular blocking agents
INTRODUÇÃO: A curarização residual está associada a maior risco de morte após anestesia. Erros diagnósticos após o uso de bloqueador neuromuscular (BNM) estão relacionados com prevalência de 65-88% de curarização residual pré-extubação traqueal (CRPE). Esse estudo analisou a decisão clínica intuitiva de usar antagonista de BNM antes da extub
Publicado em: 2010
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4. Rapid sequence intubation evaluation in a tertiary pediatric emergency department / Avaliação da sequência rápida de intubação em pronto-socorro pediátrico terciário
Os primeiros indícios de tentativas de abordagem e manejo da via aérea (VA) datam de cerca de 4000 anos. A intubação traqueal (IT) consiste na introdução de um tubo na luz da traquéia, e é responsável por salvar muitas vidas. O manejo da VA nos serviços de emergência é um dos principais desafios e seguramente um dos momentos mais críticos do cui
Publicado em: 2010
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5. Neuromuscular transmission and smooth muscle membrane properties in the guinea-pig ear artery
Effects of noradrenaline and α-adrenoceptor blocking agents on neuromuscular transmission of the guinea-pig ear artery were assessed using the micro-electrode method.
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6. Preferences of Mexican anesthesiologists for vecuronium, rocuronium, or other neuromuscular blocking agents: a survey
BioMed Central.
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7. Intra-uterine growth retardation and limb deformities produced by neuromuscular blocking agents in the rat fetus.
Intra-uterine growth retardation and limb deformities, resembling clubfoot, were produced by tubocuararine chloride, and by toxiferine, when administered to the rat fetus between the 16th and 19th day of gestation. These effects were associated in some fetuses, but were not sex-linked. Fetuses in the middle part of the uterine horn were observed to be more v
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8. Multiple receptor types for octopamine in the locust.
1. Three different pharmacological classes of octopamine receptor mediate the actions of octopamine on the locust extensor-tibiae neuromuscular preparation. A receptor classification scheme is proposed based on the results of detailed studies with agonists and antagonists. 2. Octopamine1 class receptors mediate the slowing of a myogenic rhythm found in a spe
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9. The behavioral effects of phencyclidines may be due to their blockade of potassium channels.
The action of phencyclidine [1-(1-phenylcyclohexyl)piperidine; PCP] and its behaviorally active analog (m-amino-PCP) and of two behaviorally inactive analogs [m-nitro-PCP and 1-piperidinocyclohexanecarbonitrile (PCC)] were examined in this study. In a test of spatial alternation performance in rats, PCP and m-amino-PCP were much more potent behavior modifier
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10. Effects of apamin, quinine and neuromuscular blockers on calcium-activated potassium channels in guinea-pig hepatocytes.
The bee venom peptide, apamin, has been radiolabelled with 125I, the monoiodinated derivative purified, and its binding to intact guinea-pig liver cells studied. At 37 degrees C 125I-monoiodoapamin associated with, and dissociated from, guinea-pig hepatocytes remarkably rapidly. The association and dissociation rate constants were 1.4 X 10(8) M-1 s-1 and 0.0
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11. Temperature and synaptic efficacy in frog skeletal muscle.
1. Intracellular recording and voltage-clamp techniques were used to measure synaptic efficacy and the safety factor for neuromuscular transmission in frog skeletal muscle. All measurements were made in normal Ringer solution, in the absence of presynaptic or postsynaptic blocking agents. 2. Over a broad temperature range (10-30 degrees C), a small percentag
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12. Polyneuronal innervation and quantal transmitter release in formamide-treated frog sartorius muscles.
The incidence of focal polyneuronal innervation was measured at end-plates in normal and reinnervated sartorius muscles from Rana pipiens either in the presence of curare to partially block neuromuscular transmission or in normal Ringer solution after pre-treatment with formamide to block excitation-contraction coupling. The incidence of polyneuronal innerva