Neurobiology
Mostrando 1-12 de 162 artigos, teses e dissertações.
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1. Treatment-resistant bipolar depression: concepts and challenges for novel interventions
Treatment-resistant bipolar depression (TRBD) has been reported in about one-quarter of patients with bipolar disorders, and few interventions have shown clear and established effectiveness. We conducted a narrative review of the published medical literature to identify papers discussing treatment-resistant depression concepts and novel interventions for bip
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. A review of systems biology research of anxiety disorders
The development of “omic” technologies and deep phenotyping may facilitate a systems biology approach to understanding anxiety disorders. Systems biology approaches incorporate data from multiple modalities (e.g., genomic, neuroimaging) with functional analyses (e.g., animal and tissue culture models) and mathematical modeling (e.g., machine learning) to
Braz. J. Psychiatry. Publicado em: 2021-08
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3. Unveiling the neurobiology of learning and memory: the lifetime accomplishments of Ivan Izquierdo (1937-2021)
Objective: To propose a core curriculum for religiosity and spirituality (R/S) in clinical practice for psychiatry residency programs based on the available evidence. Methods: After performing a review of studies on the implementation of R/S curricula and identifying the most commonly taught topics and teaching methods, an R/S curriculum was developed base
Braz. J. Psychiatry. Publicado em: 2021-08
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4. Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional impairment. Although effective pharmacological and non-pharmacological treatments are available, several patients with BD remain symptomatic. The advance in the
Braz. J. Psychiatry. Publicado em: 2020-10
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5. Neurobiology of suicidal behavior in combat veterans
Resumo O artigo analisa a formação profissional da enfermagem pós-1930 como parte de um processo histórico que redimensionou a profissão e sua profissionalização no Brasil. Por intermédio de documentos que remetem à experiência das primeiras alunas da Escola de Enfermagem de São Paulo, considera-se que o movimento evoca uma ruptura em relação ta
Braz. J. Psychiatry. Publicado em: 2020-10
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6. O Problema da Consciência: por Onde Começar o Estudo?
RESUMO O estudo do sistema nervoso e suas funções é fascinante e complexo. Um dos mais intrigantes assuntos deste campo é como a neurobiologia produz estados conscientes, o notório problema da consciência (cérebro e mente). Para esse estudo, são necessários conhecimentos tanto de neuroanatomia e fisiologia como de questões linguísticas e filosófi
Rev. bras. educ. med.. Publicado em: 2019-03
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7. Exploring the structural and construct validity of the Brazilian Food Cravings Questionnaire-Trait-reduced (FCQ-T-r)
Objective: Food cravings play an important role in the neurobiology of appetitive behavior, being positively associated with negative feelings, eating disorders, and obesity. This study aimed to assess the psychometric properties of the Brazilian Food Cravings Questionnaire-Trait-reduced (FCQ-T-r), a short version of the most widely used measure of this beh
Braz. J. Psychiatry.. Publicado em: 11/10/2018
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8. Challenges and developments in research of the early stages of bipolar disorder
Recently, attention in the field of bipolar disorder (BD) has focused on prevention, including early detection and intervention, as these strategies have the potential to delay, lessen the severity, or even prevent full-blown episodes of BD. Although knowledge of the neurobiology of BD has advanced substantially in the last two decades, most research was con
Rev. Bras. Psiquiatr.. Publicado em: 11/08/2016
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9. Cortical morphology changes in women with borderline personality disorder: a multimodal approach
Objective: Borderline personality disorder (BPD) is a devastating condition that causes intense disruption of patients' lives and relationships. Proper understanding of BPD neurobiology could help provide the basis for earlier and effective interventions. As neuroimaging studies of patients with BPD are still scarce, volumetric and geometric features of the
Rev. Bras. Psiquiatr.. Publicado em: 2014-03
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10. Biomarkers in mood disorders research: developing new and improved therapeutics
Background Recently, surrogate neurobiological biomarkers that correlate with target engagement and therapeutic response have been developed and tested in early phase studies of mood disorders. Objective The identification of biomarkers could help develop personalized psychiatric treatments that may impact public health. Methods These biomarkers, which are
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2014
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11. The impacts of cognitive-behavioral therapy on the treatment of phobic disorders measured by functional neuroimaging techniques: a systematic review
Objective: Functional neuroimaging techniques represent fundamental tools in the context of translational research integrating neurobiology, psychopathology, neuropsychology, and therapeutics. In addition, cognitive-behavioral therapy (CBT) has proven its efficacy in the treatment of anxiety disorders and may be useful in phobias. The literature has shown t
Rev. Bras. Psiquiatr.. Publicado em: 2013-09
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12. Mild environmental intervention in mother-infant interactions reduces social play behavior in rats
During early life, animals are sensitive to environmental events that may lead to short-term and long-lasting changes in their neurobiology and behavior, which could be related to increased risk for psychopathology. Neonatal handling is an experimental intervention in the mother-infant relationship. Based on previous studies, it is known to decrease rat pups
Psychol. Neurosci.. Publicado em: 2013-06