Neural Tube Defect
Mostrando 1-12 de 57 artigos, teses e dissertações.
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1. Decreased respiratory performance of children and adolescents with myelomeningocele who use a wheelchair – preliminary data
Myelomeningocele (MMC) is a neural tube defect that often causes spinal cord injury at the thoracolumbar region, as well as sensory and motor paralysis in the lower limbs. This leads to continuous use of a wheelchair and, consequently, a sedentary lifestyle, predisposition to muscle weakness, cardiovascular and respiratory disorders, obesity, and structural
Braz J Med Biol Res. Publicado em: 05/08/2019
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2. PERFIL EPIDEMIOLÓGICO E NÍVEL SÉRICO DE ÁCIDO FÓLICO EM MÃES DE CRIANÇAS PORTADORAS DE DEFEITO DO TUBO NEURAL. / EPIDEMIOLOGICAL PROFILE AND SERUM FOLATE IN MOTHERS OF CHILDREN WITH NEURAL TUBE DEFECT.
O defeito do tubo neural (DTN), que é uma malformação congênita, participa de modo considerável nas estatísticas de morbidade e mortalidade perinatais devido a suas elevadas taxas de incidência. Os DTN, podem se limitar ao sistema nervoso central e/ou periférico, e também podem incluir os tecidos sobrejacentes (ossos, músculos e tecido conjuntivo).
Publicado em: 2011
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3. Health-related quality of life of children and adolescents with meylomeningocele / Qualidade de vida relacionada à saúde em crianças e adolescentes com mielomeningocele
Myelomenigocele (MM) is the most common and disabling disorder of neural tube defects. It is associated to several health problems and to motor and sensitive disabilities. This condition may impair patients health-related quality of life (HRQL). However, it is not established how different neurological lesion levels and functional ambulation influence HRQL.
Publicado em: 2009
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4. CÉLULAS TRONCO AUTÓLOGAS DE MEDULA ÓSSEA NA REGENERAÇÃO DO NERVO TIBIAL DE COELHOS MEDIANTE TÉCNICA DE TUBULIZAÇÃO COM PRÓTESE DE SILICONE / AUTOLOGOUS STEM CELLS FROM BONE MARROW IN THE REGENERATION OF TIBIAL NERVE OF RABBITS USING THE TUBULIZATION TECHNIQUE WITH SILICONE TUBE
This study presents an experimental model of an acute defect in a peripheral nerve to evaluate neural regeneration using a tubulization technique associated with the inoculation of autologous stem cells from bone marrow. A total of 12 New Zealand white rabbits underwent a bilateral dissection of the tibial nerve followed by repair with silicone tubulization.
Publicado em: 2007
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5. Etanol, deficiência de ácido fólico e associação desses dois fatores durante a gestação de camundongos swiss / Etanol, Deficiency of Acid Fólico and Association Of these Two Factors During the Gestation of Swiss Mice
In spite of the well known teratogenic effect of ethanol, it is still the most consumed exogenous abuse substance by women of reproductive age. Ethanol also impairs the absorption, transport and metabolism of folic acid. The aim of this study was to investigate the effects of ethanol, dietary deficiency of folic acid and the association of both on the outcom
Publicado em: 2007
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6. Chimerism 47,XY,+21/46,XX in a female infant with anencephaly and other congenital defects
Chimerism is rare in humans and is usually discovered accidentally when a 46,XX and 46,XY karyotype is found in a same individual. We describe a malformed female infant with neural tube defect (NTD) and a 47,XY,+21[5]/46,XX[30] karyotype.
Genetics and Molecular Biology. Publicado em: 2006
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7. Changing trend of neural tube defects in eastern Turkey.
STUDY OBJECTIVE--The aim was to study the relationship between birth prevalence of neural tube defect (including anencephaly) in Eastern Turkey before and after the Chernobyl disaster. DESIGN--This was a prospective study of time trends in live births and stillbirths over the years 1985-1990. Medical and sociodemographic data were recorded for the mothers. S
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8. Further evidence for an intermittent pattern of neural tube closure in humans.
Evidence is presented to support the recent suggestion that human neural tube closure is similar to that observed in mice, and comprises several regionally distinct closure sites rather than being a simple zipping up process. Seven subjects, each with more than one neural tube defect (NTD), are described. Comparative studies of the location of the lesions in
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9. Neural tube defects and abnormal brain development in F52-deficient mice.
F52 is a myristoylated, alanine-rich substrate for protein kinase C. We have generated F52-deficient mice by the gene targeting technique. These mutant mice manifest severe neural tube defects that are not associated with other complex malformations, a phenotype reminiscent of common human neural tube defects. The neural tube defects observed include both ex
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10. Recurrence risk after neural tube defects in a genetic counselling clinic.
The recurrence of isolated neural tube defects in a population of women from a genetic counselling clinic was found to be 3.4%. After one baby with a neural tube defect the recurrence was 2.3%. Of the 15 pregnancies of women who had two previous babies with neural tube defects, there were three further recurrences. These findings show that the Hungarian recu
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11. Neural tube defect recurrence after 'partial' vitamin supplementation.
A total of 227 mothers enrolled for periconceptional multivitamin supplementation because of previous neural tube defect (NTD) births took vitamins for less than the recommended minimum period (at least 28 days before conception until two menstrual periods have been missed). Of 213 examined infants/fetuses born to these partially supplemented mothers, two ha
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12. Prenatal diagnosis of a neural tube defect: Meckel syndrome.
A severe neural tube defect diagnosed in a 191/2-week-old "at risk" fetus on the evidence of a markedly elevated alpha-fetoprotein level in the amniotic fluid, turned out to be an occipital myelocoele. However, the fetus also had polycystic kidneys and postaxial hexadactyly on all extremities. The karyotype was normal. These are the features of the rare Meck