Neonate Mice
Mostrando 1-12 de 32 artigos, teses e dissertações.
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1. Passive acquisition of protective antibodies reactive with Bordetella pertussis by the newborn via placental transfer and breastfeeding / Aquisição passiva de anticorpos protetores reativos com Bordetella pertussis pelo recém-nascido via transferência placentária e aleitamento materno
Pertussis is currently considered an important public health problem in developed countries. Although there is no evidence of an increase in the number of pertussis cases in our country, can not rule out the hypothesis of a future re-emergence of disease, as epidemiological data from some regions show an increase in incidence, indicating that probably there
Publicado em: 2010
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2. Efeito imunomodulatório in vivo e in vitro do oligodeoxinucleotídeo CpG na imunização com ovalbumina em camundongos nas fases neonatal e adulta. / In vivo and in vitro immunomodulatory effect of CpG-containing oligodeoxynucleotide in ovalbumin immunization of newborn and adult mice.
The allergy development may occur in the early life, during the pregnancy or postnatally at the first months of life. In mice, it is described a predisposition to Th2 biased response in the neonatal period, favoring the development of allergic response. The maturation of functions related to Th1 response by the use of immune adjuvants may be beneficial to th
Publicado em: 2009
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3. Imunogenicidade da vacina de DNA quimérica LAMP-1/p55Gag do HIV-1 no período neonatal e efeito da imunização materna na resposta vacinal da prole de camundongos. / Immunogenicity of LAMP-1/p55Gag of HIV-1 DNA chimeric vaccine on neonatal period and effect of maternal immunization immune response of vaccinated offspring.
The immunogenicity of LAMP/gag DNA vaccine of HIV-1, which target the antigen to the class II MHC compartment, was evaluated on BALB/c neonate mice and also the effect of maternal immunization on off spring vaccine response was analyzed. The LAMP/gag neonatal vaccination elicited IgG antibody anti-Gag production and augment the IFN-g producing cells to the M
Publicado em: 2009
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4. Estudo da imunogenicidade da proteína de classe 3 (PorB) purificada da membrana externa de Neisseria miningitidis: imunização intranasal/intramuscular em camundongos adultos e neonatos utilizando Bordetella pertussis como adjuvante. / Study of the immunogenecity of the class 3 proteins (PorB) purified from the outer mebrane of Neisseria meningitidis: intranasal and intramuscular immunization in adult and neonate mice using Bordetella pertussis as adjuvant.
Proteins of class 3 sound candidates in the preparation of vaccine against meningococcal illness. The aim of this study was to determine the immunogenicity of class 3 proteins purified of Neisseria meningitidis of the serogroup B along with whole cells of Bordetella pertussis as adjuvant. BALB/c and outbred neonate mice between 3 and 12 days old were immuniz
Publicado em: 2008
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5. Nasal immunization with outer membrane antigens of Neisseria meningitidis B selected for the highest expression of the immunotype of LPS 3,7,9 with monoclonal antibodies and Bordetella pertussis as adjuvants in neonates mice. / Imunização nasal com antígenos de membrana externa de Neisseria meningitidis B selecionados para a maior expressão do imunotipo de LPS 3, 7, 9 com anticorpos monoclonais e Bordetella pertussis como adjuvante em camundongos neonatos.
The natural habitat of Neisseria meningitidis is the human nasopharynx, and the bacterium is transmitted by direct mouth-to-mouth contact or by the inhalation of released mucous particles during close contact. N meningitidis is a Gram-negative bacterium responsible for significant mortality worldwide. While effective polysaccharide-based vaccines exist again
Publicado em: 2008
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6. Study of immunogenicity of Neisseria lactamica antigens: use of monoclonal antibodies. / Estudo da imunogenicidade de antígenos de Neisseria lactamica: utilização de anticorpos monoclonais.
Immunological and epidemiological evidences suggest that the development of natural immunity to meningogoccal disease may be associated with crossreactive antigens together with Neisseria meningitidis and other commensal bacteria, like Neisseria lactamica. The present study aimed to investigate the immunogenicity of antigens of outer membrane vesicles (OMV)
Publicado em: 2008
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7. Estudo histolÃgico e morfomÃtrico do disco epifisÃrio de ratos neonatos tratados com fluoxetina
The selective inhibitors of the re-uptake of the serotonin acts increasing the availability of this neurotransmitter in the synaptic cleft. Recent studies demonstrated the presence of receptors of serotonin in bone cells, suggesting the participation of this substance in the bone metabolism. The aim of this study is to verify the effects of the use of fluoxe
Publicado em: 2004
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8. Injeções intradermicas de colageno e suas implicações na matriz extracelular
In the present work the extracellular matrix responses to intradermic heterologous collagen injections and the evaluation of the effects of the injected material physically and chemically treated were studied. Mice were injected with type 1 bovine collagen (gel, gel formolized and lyophyllized collagen solutions) and sacrificed at different intervals of time
Publicado em: 1987
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9. Enhancement of the neonate's nonspecific immunity to Klebsiella infection by muramyl dipeptide, a synthetic immunoadjuvant.
N-acetylmuramyl-L-alanyl-D-isoglutamine (muramyl dipeptide) and certain derivatives that are structural analogs of part of the bacterial peptidoglycan monomer have been shown to be adjuvant active and to enhance the nonspecific immunity of adult mice infected by Klebsiella pneumoniae. In the present study muramyl dipeptide and two other synthetic analogs wer
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10. Listeriolysin as a virulence factor in Listeria monocytogenes infection of neonatal mice and murine decidual tissue.
Listeriolysin is a 60-kDa protein which allows the growth of Listeria monocytogenes in macrophages and other cells and has been shown to be a virulence factor in Listeria infections of adult mice. However, the neonate and fetoplacental unit are major populations susceptible to listeriosis. Recent data indicate that macrophage and T-cell functions are markedl
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11. Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells.
Frequencies of 25 immunoglobulin heavy-chain and kappa light-chain variable (VH + V kappa) gene-family pairings expressed in splenic B-cell populations were determined by hybridization of VH- and V kappa-family-specific DNA probes to mitogen-induced B-cell colonies from C57BL/6 mice or hybridomas derived from BALB/c and NZB mice. Both analyses support the co
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12. Glucocorticoids are insufficient for neonatal gene induction in the liver
Glucocorticoids and their receptor (GR) play a key role in perinatal gene induction. In the liver, the GR is essential for the neonatal induction of a number of genes, including that coding for tyrosine aminotransferase (TAT). To assess the function of the GR in the perinatal period, we have compared the activity of two types of glucocorticoid responsive ele
The National Academy of Sciences.