Natural Killer T Cells
Mostrando 1-12 de 530 artigos, teses e dissertações.
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1. Plasmacytoid dendritic cells in dermatology,
Abstract Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and dendritic cells and inducing activation and migration of natural killer cells. Plasmacytoid dendritic cel
An. Bras. Dermatol.. Publicado em: 2021-02
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2. Aquios CL flow cytometer performance in the automated quantification of lymphocyte subpopulations
RESUMO A citometria de fluxo (CF) é uma ferramenta importante para diagnóstico, prognóstico e acompanhamento terapêutico de diversas neoplasias hematológicas. Além disso, possibilita a quantificação das subpopulações linfocitárias (SPL) para assistência diagnóstica e monitoramento das imunodeficiências primárias e adquiridas por meio das expre
J. Bras. Patol. Med. Lab.. Publicado em: 02/09/2019
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3. The role of GNLY gene polymorphisms in psoriasis pathogenesis
Abstract BACKGROUND: Psoriasis is a systemic inflammatory disorder that involves complex pathogenic interactions between the innate and adaptive immune systems. The most accepted mechanism in the etiopathogenesis of psoriasis is the induction of inflammation with keratinocyte hyperproliferation. Granulysin (GNLY) is a cytolytic antimicrobial peptide (AMP) t
An. Bras. Dermatol.. Publicado em: 09/05/2019
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4. Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis
Abstract: Skin's innate immunity is the initial activator of immune response mechanisms, influencing the development of adaptive immunity. Some contact allergens are detected by Toll-like receptors (TLRs) and inflammasome NLR3. Keratinocytes participate in innate immunity and, in addition to functioning as an anatomical barrier, secrete cytokines, such as TN
An. Bras. Dermatol.. Publicado em: 2018-03
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5. Analysis of CD57+ natural killer cells and CD8+ T lymphocytes in periapical granulomas and radicular cysts
Abstract: The aim of this study was to compare the number of CD57+ natural killer (NK) cells and CD8+ T lymphocytes between periapical granulomas (PGs) and radicular cysts (RCs). Twenty-fives cases of PGs and 25 of RCs were submitted to histological analysis and immunohistochemistry using anti-CD57 and anti-CD8 biomarkers. Positive cells were counted in 10 f
Braz. oral res.. Publicado em: 18/12/2017
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6. Cytotoxic activity in cutaneous leishmaniasis
Cutaneous leishmaniasis (CL) is a chronic disease caused by species of the protozoan Leishmania and characterised by the presence of ulcerated skin lesions. Both parasite and host factors affect the clinical presentation of the disease. The development of skin ulcers in CL is associated with an inflammatory response mediated by cells that control parasite gr
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-11
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7. Association between interleukin-22 genetic polymorphisms and bladder cancer risk
OBJECTIVE:The cytokine interleukin-22 (IL-22), which is produced by T cells and natural killer cells, is associated with tumorigenesis and tumor progression in cancers. However, the role of IL-22 in bladder cancer has not been investigated.MATERIALS AND METHODS:A prospective hospital-based case-control study comprising 210 patients with pathologically proven
Clinics. Publicado em: 2015-10
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8. Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
PURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG a
Acta Cir. Bras.. Publicado em: 2013-03
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9. Immunological characteristics of mesenchymal stem cells
Although bone marrow is the main source, mesenchymal stem cells have already been isolated from various other tissues, such as the liver, pancreas, adipose tissue, peripheral blood and dental pulp. These plastic adherent cells are morphologically similar to fibroblasts and have a high proliferative potential. This special group of cells possesses two essenti
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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10. Variantes do gene CD226 associadas com a susceptibilidade ao diabetes mellitus tipo 1 autoimune / CD226 gene variants associated with susceptibility to type 1, immune mediated, diabetes
Recently, Genome Wide Association (GWA) studies identified a new locus, 18q22, as a canditate to Type 1 A, or immune mediated diabetes (T1AD) susceptibility. This locus harbors the CD226 gene, responsible for encoding the leukocyte adhesion molecule (CD226) involved in cell adhesion, differentiation of naïve CD4+T cells, cytotoxicity induced by natural kill
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/08/2012
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11. Estudo das subpopulaÃÃes linfocitÃrias em sangue perifÃrico de pacientes com hansenÃase / Study of lymphocyte subpopulations in peripheral blood of patients with leprosy
A hansenÃase à uma doenÃa infecciosa crÃnica causada pelo Mycobacterium leprae, um bacilo Ãlcool-Ãcido resistente. Tem alta infectividade, porÃm baixa patogenicidade, e quando se manifesta, apresenta-se sob uma grande diversidade de formas clÃnicas. Essa diversidade depende, em grande parte, da resposta imunolÃgica do hospedeiro, sendo os linfÃcito
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/05/2012
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12. Caracterização das células T Natural Killer de células mononucleares de sangue periférico em indivíduos de diferentes continentes / Characterization of T cells Natural Killer (NKT) cells in peripheral blood mononuclear cells of healthy individuals from different continents
As células T Natural Killer (NKT) são linfócitos que expressam o rearranjo V24V11 com TCR invariante e reconhecem glicolipídeos como o alfagalactosilceramida (-GalCer) apresentado no contexto da molécula MHC-não clássica chamada CD1d. As NKT são divididas em subgrupos distintos: os fenótipos CD4+ e CD4- em camundongos e humanos, e CD8+ e CD4-CD8- em
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/03/2012