Myogenesis
Mostrando 1-12 de 261 artigos, teses e dissertações.
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1. Six1 induces protein synthesis signaling expression in duck myoblasts mainly via up-regulation of mTOR
Abstract As a critical transcription factor, Six1 plays an important role in the regulation of myogenesis and muscle development. However, little is known about its regulatory mechanism associated with muscular protein synthesis. The objective of this study was to investigate the effects of overexpression ofSix1 on the expression of key protein metabolism-re
Genet. Mol. Biol.. Publicado em: 2016-03
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2. Differentially expressed genes and miRNA identification in pig skeletal muscle / Identificação de genes diferencialmente expressos e miRNAs em músculo esquelético de suínos
The pig (Sus scrofa) is considered an important animal for meat production. This interest revolves around the potential for muscle growth, which usually is associated with certain characteristics during prenatal myogenesis. To study the genes responsible for these characteristics, expressed sequence tags (EST) provide direct information about the transcripto
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/07/2011
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3. Perfil transcricional durante o desenvolvimento muscular esquelético de suínos de uma raça local Brasileira e dois grupos genéticos comerciais / Transcriptional profiling during pig skeletal muscle development of a Brazilian local breed and two commercial genetic groups
O desenvolvimento esquelético muscular é um processo complexo que envolve a expressão coordenada de milhares de genes. O objetivo deste estudo foi identificar genes diferencialmente expressos no músculo longissimus dorsi (LD) de suínos, bem como seus padrões de expressão entre cinco estádios do desenvolvimento. Primeiramente, uma análise de microarr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/10/2010
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4. Effects of strain and age on ear wound healing and regeneration in mice
Round holes in the ears of MRL mice tend to close with characteristics of regeneration believed to be absent in other mouse strains (e.g., C57BL/6). We evaluated the kinetics and the histopathology of ear wound closure in young (8 weeks old) C57BL/6 and BALB/c mice. We also used middle-aged (40 weeks old) C57BL/6 mice to evaluate the influence of aging on th
Brazilian Journal of Medical and Biological Research. Publicado em: 20/11/2009
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5. Identificação de microRNAs na musculatura esquelética de Gallus gallus / Identification of microRNAs from Gallus gallus skeletal muscle
MicroRNAs (miRNAs) represent a class of small and noncoding RNAs, about 20-nucleotides long that negatively regulate gene expression posttranscriptionally. The regulatory action of these molecules is essential for the proper functioning of various biological processes, including the development and maintenance of skeletal muscles. To identify miRNAs that mig
Publicado em: 2009
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6. Identificação e caracterização funcional dos elementos cis-regulatorios da miostatina / Identification and functional characterization of the cis-regulatory elements of myostatin
The Myostatin protein (also known as GDF8) is a member of the transforming growth factor-β (TGF-β) superfamily and is expressed almost exclusively in skeletal muscle, both in the embryo and in the adult, where the protein circulates in the blood flow. It was initially identified in 1997 by MCPHERRON et al., and since then many studies have been dem
Publicado em: 2009
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7. Avaliação do padrão de degeneração e regeneração muscular em diferentes modelos murinos para distrofias musculares progressivas / Study of degeneration and regeneration pathways, in mice models for muscular dystrophies
The muscular dystrophies are a heterogeneous group of genetic diseases characterized by progressive and irreversible degeneration of skeletal muscles. Muscle weakness is the consequence of an imbalance between successive cycles of degeneration and regeneration, with further replacement of the degraded muscle fibers by adipose and connective tissues. Several
Publicado em: 2009
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8. The effect of SHP-2 silencing in the activity of FAK during myogenesis / Efeito do silenciamento da SHP-2 na atividade da FAK durante a miogenese do musculo esqueletico
Os mioblastos que formam o músculo esquelético são derivados de regiões do miótomo dos somitos. No processo de miogênese ocorre transição de estado proliferativo para um estado de diferenciação que se caracteriza por interrupção do ciclo celular, expressão de genes músculo-específico, reconhecimento célula-célula e formação de miotubos mul
Publicado em: 2008
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9. O gene da miogenina: sequenciamento em suínos e análise filogenética / The myogenin gene: sequencing in swine and phylogenetic analysis
Meat production capacity is related to muscle fibers number show in newborn animals. The muscle fibers are formed in the myogenesis that takes place during the embryonic development, an event that is controlled in part by the MyoD gene family. The Myogenin gene is a member of this family and rules the expression of muscle specific genes. It has an important
Publicado em: 2005
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10. Investigation of polymorphisms of myogenic factors and myostatin genes as molecular markers for quantitative traits in Gallus gallus. / Investigação de polimorfismos nos genes dos fatores Miogênicos e Miostatina como marcadores moleculares para características quantitativas em Gallus gallus.
The aim of this work was to identify polymorphisms in five candidate genes (MyoD, Myf5, Myogenin, MRF4 and Myostatin) which act in chicken muscle development and evaluate the effects of its allelic variants on growth and muscle development quantitative traits. MyoD and Myf5 are essential for the determination of the myogenic lineage of muscle precursor cells
Publicado em: 2005
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11. Cytoskeletal and cellular adhesion proteins in zebrafish (Danio rerio) myogenesis
The current myogenesis and myofibrillogenesis model has been based mostly on in vitro cell culture studies, and, to a lesser extent, on in situ studies in avian and mammalian embryos. While the more isolated artificial conditions of cells in culture permitted careful structural analysis, the actual in situ cellular structures have not been described in detai
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-08
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12. Influence of the neural tube/notochord complex on MyoD expression and cellular proliferation in chicken embryos
Important advances have been made in understanding the genetic processes that control skeletal muscle formation. Studies conducted on quails detected a delay in the myogenic program of animals selected for high growth rates. These studies have led to the hypothesis that a delay in myogenesis would allow somitic cells to proliferate longer and consequently in
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02