Myocardium Metabolism
Mostrando 1-12 de 43 artigos, teses e dissertações.
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1. Previous exercise training increases levels of PPAR-α in long-term post-myocardial infarction in rats, which is correlated with better inflammatory response
OBJECTIVE: Exercise is a protective factor for cardiovascular morbidity and mortality, with unclear mechanisms. Changing the myocardial metabolism causes harmful consequences for heart function and exercise contributes to metabolic adjustment modulation. Peroxisome proliferator-activated receptors (PPARs) are also myocardium metabolism regulators capable of
Clinics. Publicado em: 2016-03
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2. Paraoxonase1 gene polymorphisms as predictors of cardiovascular events in stable coronary artery disease / Polimorfismos no gene paraoxonase 1 como preditores de eventos cardiovasculares em pacientes com doença coronária estável
Paraoxonase 1 (PON1) gene polymorphisms have a known relation with lipid metabolism, conferring a marginal and modest effect on serum lipoprotein concentrations and also on development of coronary artery disease (CAD). The primary objective of this study is to investigate the association between PON1 polymorphisms: R192Q- rs662, R160G: rs13306698, Leu55Met:
Publicado em: 2010
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3. Análise proteômica no miocárdio de pacientes com cardiomiopatia chagásica crônica: alterações no metabolismo energético cardíaco / Proteomic Analysis in the myocardium from patients with chronic Chagas disease cardiomyopathy: alterations in the cardiac energy metabolism
A patogênese da Cardiomiopatia Chagásica Crônica (CCC) ainda é assunto de intenso debate. A CCC apresenta intenso infiltrado inflamatório no tecido cardíaco, onde os linfócitos T infiltrantes produzem citocinas inflamatórias, como IFN-gama e TNF-alfa. Adicionalmente, pacientes com CCC apresentam um pior prognóstico quando comparados aos portadores d
Publicado em: 2010
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4. New method in myocardial viability detection with 18F-fluoro-desoxi-glucose using a low-carbohydrate diet: a comparative study with euglycemic hyperinsulinemic clamp / Nova técnica para pesquisa de viabilidade miocárdica com 18F-fluoro-desoxi-glicose utilizando dieta restrita em carboidratos: estudo comparativo com o clamp hiperinsulínico euglicêmico
INTRODUÇÃO: Em pacientes com infarto do miocárdio (IM) e disfunção cardíaca, a evidência de viabilidade miocárdica é primordial, e o exame tomográfico por emissão de pósitrons com 18F-fluoro-desoxi-glicose (18FDG-PET) é o padrão-ouro para essa identificação. Existe preferência, na literatura, pela realização do clamp hiperínsulínico eugl
Publicado em: 2008
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5. Proteomic inventory of myocardial proteins from patients with chronic Chagas' cardiomyopathy
Chronic Chagas' disease cardiomyopathy (CCC) is an often fatal outcome of Trypanosoma cruzi infection, with a poorer prognosis than other cardiomyopathies. CCC is refractory to heart failure treatments, and is the major indication of heart transplantation in Latin America. A diffuse myocarditis, plus intense myocardial hypertrophy, damage and fibrosis, in th
Brazilian Journal of Medical and Biological Research. Publicado em: 30/10/2006
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6. MITOCHONDRIAL PROTEIN EXPRESSION IN NATURAL AND INDUCED FORMS OF CANINE DILATED CARDIOMYOPATHY
Idiopathic dilated cardiomyopathy (DCM) is now widely regarded as a syndrome in which a variety of etiological and predisposing factors give rise to myocardial dysfunction ultimately reflected in a similar pathological condition. DCM is the most well-known myocardial disease in dogs characterized by ventricular dilation and diminished cardiac function. The p
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2005
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7. Positron emission tomography with oxygen-15 of stunned myocardium caused by coronary artery vasospasm after recovery.
Stunned myocardium is often observed after unstable angina, myocardial infarction, thrombolysis, angioplasty, and bypass surgery but rarely after coronary vasospasm. A case of stunned myocardium caused by diffuse coronary artery vasospasm and mimicking myocardial infarction is reported. The patient had an emergency coronary angiography, which showed no patho
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8. Derangements in myocardial purine and pyrimidine nucleotide metabolism in patients with coronary artery disease and left ventricular hypertrophy.
Studies in animal models of myocardial ischemia and left ventricular hypertrophy have demonstrated a number of derangements in purine and pyrimidine nucleotide content of myocardium that are postulated to play a role in the pathogenesis of muscle dysfunction in these disorders. The present study examined myocardium of patients with coronary artery disease, l
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9. Incidence of hibernating myocardium after acute myocardial infarction treated with thrombolysis.
OBJECTIVE: To establish the incidence of hibernating myocardium after myocardial infarction treated with thrombolysis and to observe differences in the clinical outcome between patients with and without hibernating tissue. METHODS: 41 patients underwent gated positron emission tomography with 18-fluorodeoxyglucose and 13N-ammonia at a median of eight days af
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10. Impairment of energy metabolism in intact residual myocardium of rat hearts with chronic myocardial infarction.
The purpose of this study was to test the hypothesis that energy metabolism is impaired in residual intact myocardium of chronically infarcted rat heart, contributing to contractile dysfunction. Myocardial infarction (MI) was induced in rats by coronary artery ligation. Hearts were isolated 8 wk later and buffer-perfused isovolumically. MI hearts showed redu
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11. Metabolic fate of extracted glucose in normal human myocardium.
Glucose is an important substrate for myocardial metabolism. This study was designed to determine the effect of circulating metabolic substrates on myocardial glucose extraction and to determine the metabolic fate of glucose in normal human myocardium. Coronary sinus and arterial catheters were placed in 23 healthy male volunteers. [6-14C]Glucose was infused
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12. Nuclear magnetic resonance spectroscopy of excised human hearts
Background—Phosphorus nuclear magnetic resonance spectroscopy has been proposed as a method of studying the metabolism of the myocardium in patients. Little is known about 31P nuclear magnetic resonance spectroscopy of diseased human hearts.