Myelopoiesis
Mostrando 1-12 de 73 artigos, teses e dissertações.
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1. Avaliação do potencial anti-inflamatório agudo e crônico e imunossupressor do extrato etanólico de Pterodon polygalaeflorus através de estudos in vivo e in vitro / Evaluation of the acute and chronic potential antiinflammatory and immunosupressive of ethanolic extract of Pterodon polygalaeflorus through in vivo and in vitro studies
O gênero Pterodon pertence à família das Papilonaceas e inclui cinco espécies nativas do Brasil: P. pubescens Benth., P. emarginatus Vog., P. apparicioi Pedersoli e P. abruptus Benth., sendo a espécie objeto deste estudo a P. polygalaeflorus Benth.. Seus frutos são livremente comercializados em mercados da flora medicinal e utilizados pela medicina pop
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2011
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2. Avaliação de solução hidro alcoolica de propolis na resposta hematopoetica em camundongos infectados com Listeria monocytogenes / Evaluation of hydro alcoholic solution of propolis on the hematopoietic response in Listeria Monocytogenes
Infection with Listeria monocytogenes has proven to be a useful model to investigate early effects of new compounds on the immune response to intracellular bacteria. In particular, the number of hematopoietic cells in the bone marrow and spleen is critically important to resistance to this infection. In this study, we demonstrated the protective effects of h
Publicado em: 2009
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3. Mielopoese em camundongos geneticamente selecionados para alta ou baixa reatividade inflamatória aguda. / Myelopoiesis in mice genetically selected for high or low acute inflammatory response.
Mice AIRmax and AIRmin exhibit significant differences in the average number of migrating leukocytes and in the protein content of inflammatory exudate produced by polyacrylamide particles. This higher inflammatory capacity of the AIRmax mice is due to three convergent factors: higher local production of chemotactic factors, increased resistance of locally i
Publicado em: 2008
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4. Estudo da atividade imunomoduladora do extrato de Maytenus ilicifolia em animais infectados com Listeria monocytogenes
In this work, we have investigated the effects of Maytenus ilicifolia Mart. ex Reissek (ES) extract on the growth and differentiation of bone marrow and spleen granulocyte- macrophage progenitor cells (CFU-GM), serum colony stimulating activity (CSA), natural killer (NK) cell activity and IFN-y production in a Listeria monocytogenes infected mice.A significa
Publicado em: 2003
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5. Avaliação de alguns aspectos da resposta imune tipo celular em animais portadores do tumor ascitico de Ehrlich e tratados com titanocenos
In this work, as a continuation of previous studies in our laboratory, we investigated the effects of the titanocene dicyclopentadienyldichlorotitanium IV compound, DDCT, (15 mg/kg/day/ per two days) on the natural killer cell activity (NK) and on Th1 [interleukin (IL)-2 and interferon-g (IFN-g)] and Th2 (IL-4 and IL-10) responses in normal and Ehrlich ascit
Publicado em: 2002
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6. Modulação de parametros imunologicos da resposta não especifica pelo composto MAPA
ln this work, we investigated the effeets of MAPA on the immune response. We have stlldied the neutrophils exposed to these eompound of six normal individuaIs. Phagoeytosis and killing of Candida albicans and Candida ke.fyr by neutrophils, neutrophil ehemotaxis and nitroblue tetrazolium reduetion were measured. The results obtained demonstrated - an inerease
Publicado em: 1999
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7. Transient abnormal myelopoiesis accompanied by hepatic fibrosis in two infants with Down syndrome.
Two necropsy cases of Down syndrome are reported. These showed transient abnormal myelopoiesis accompanying characteristic hepatic sinusoidal fibrosis. Numerous megakaryocytes were found in the liver of one case, but not in the other. Only eight cases of Down syndrome with simultaneous occurrence of hepatic fibrosis and transient abnormal myelopoiesis have b
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8. Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.
The influence of ofloxacin and pefloxacin on human myelopoiesis in vitro was investigated. Drug concentrations varied from 0.5 to 50 micrograms/ml, and the effect on granulomonocyte precursors was evaluated on cell cultures in agar. Our results indicate that ofloxacin and pefloxacin do not induce inhibition of myelopoiesis.
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9. Two different functions for CD44 proteins in human myelopoiesis.
CD44 is important during myelopoiesis, although the contributions of variant CD44 proteins are unclear. We show here that in human long-term bone marrow culture antibodies recognizing a CD44 NH2-terminal epitope (mab 25-32) or a CD44v6 epitope (mab VFF18) inhibit myelopoiesis. However, mab 25-32 but not mab VFF18 affects myeloid colony formation. These data
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10. Ferritin stimulation of a monokine inhibitor of lipopolysaccharide-augmented myelopoiesis is ferroxidase dependent.
Ferritin inhibition of myelopoiesis has been associated with intrinsic ferroxidase activity of heavy-chain ferritin and with production of a monokine inhibitor of lipopolysaccharide (LPS)-augmented monocytopoiesis. We report here that intrinsic ferroxidase activity of heavy-chain ferritin is required for stimulated production of the monokine inhibitor of LPS
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11. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
The chemokine stromal cell-derived factor 1, SDF-1, is an important regulator of leukocyte and hematopoietic precursor migration and pre-B cell proliferation. The receptor for SDF-1, CXCR4, also functions as a coreceptor for T-tropic HIV-1 entry. We find that mice deficient for CXCR4 die perinatally and display profound defects in the hematopoietic and nervo
The National Academy of Sciences.
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12. Altered myelopoiesis and the development of acute myeloid leukemia in transgenic mice overexpressing cyclin A1
A mammalian A-type cyclin, cyclin A1, is highly expressed in testes of both human and mouse and targeted mutagenesis in the mouse has revealed the unique requirement for cyclin A1 in the progression of male germ cells through the meiotic cell cycle. While very low levels of cyclin A1 have been reported in the human hematopoietic system and brain, the si
The National Academy of Sciences.