Mycobacterium Leprae
Mostrando 13-24 de 586 artigos, teses e dissertações.
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13. Spatial modeling of leprosy in the state of Bahia and its social determinants: a study of health inequities
Abstract BACKGROUND: Leprosy is a neglected disease caused by Mycobacterium leprae. Brazil has the second largest number of cases in the world. OBJECTIVES: To analyze the spatial distribution of leprosy in the state of BAHIA, Brazil, and the association between his occurrence and the synthetic indicators of municipal socioeconomic performance, social vulne
An. Bras. Dermatol.. Publicado em: 09/05/2019
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14. De novo histoid leprosy in a Colombian patient with multiple skin nodules on the ears and extremities
Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemi
Rev. Soc. Bras. Med. Trop.. Publicado em: 14/02/2019
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15. Reading of the Mitsuda test: comparison between diameter and total area by means of a computerized method
ABSTRACT The Mitsuda test is a skin test based on the individual’s immune response through late and highly specific hypersensitivity reaction to the Mycobacterium leprae bacillus. A negative reaction identifies individuals who present a higher risk of becoming ill if exposed to M. leprae and, if they become ill, to develop the virchowian form of disease. T
Rev. Inst. Med. trop. S. Paulo. Publicado em: 14/02/2019
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16. Polymorphisms in the TGFB1 and IL2RA genes are associated with clinical forms of leprosy in Brazilian population
BACKGROUND Leprosy is a chronic infectious disease caused by Mycobacterium leprae, and compromises the skin and peripheral nerves. This disease has been classified as multibacillary (MB) or paucibacillary (PB) depending on the host immune response. Genetic epidemiology studies in leprosy have shown the influence of human genetic components on the disease out
Mem. Inst. Oswaldo Cruz. Publicado em: 10/12/2018
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17. Utility of immunoglobulin isotypes against LID-1 and NDO-LID for, particularly IgG1, confirming the diagnosis of multibacillary leprosy
BACKGROUND Leprosy remains a health problem in many countries, with difficulties in diagnosis resulting in delayed treatment and more severe disabilities. Antibodies against several Mycobacterium leprae antigens have, however, shown value as diagnostic and/or prognostic markers. OBJECTIVES The objective of this study was to evaluate serum immunoglobulin
Mem. Inst. Oswaldo Cruz. Publicado em: 26/02/2018
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18. Polyhexanide 0.2% in treatment of trophic foot ulcers in leprosy - preliminary study
Abstract: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which affects peripheral nerves, skin and mucous membranes. The impairment of neural function as well as sensory or sensory-motor disabilities in leprosy continue to be a problem that requires careful attention in the management of patients with the aim to avoid or minimize the
An. Bras. Dermatol.. Publicado em: 2018-02
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19. Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae
BACKGROUND The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. OBJECTIVE The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local population in five municipalities in the state of Ceará,
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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20. ELISA-based assay of immunoglobulin G antibodies against mammalian cell entry 1A (Mce1A) protein: a novel diagnostic approach for leprosy
BACKGROUND Leprosy is a chronic infectious disease caused by the obligate intracellular bacillus Mycobacterium leprae. Because leprosy diagnosis is complex and requires professional expertise, new tools and methodologies are needed to detect cases in early stages and prevent transmission. The M. leprae genome contains mce1A, which encodes a putative mammali
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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21. Salivary anti-PGL-1 IgM may indicate active transmission of Mycobacterium leprae among young people under 16 years of age
Abstract Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection. The study aimed to analyze salivary anti-PGL-1 IgA and IgM antibodies in 169 children aged 4-16 years old, who lived nearby or inside the house of multibacillary or
Braz J Infect Dis. Publicado em: 2017-10
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22. Specific antigen serologic tests in leprosy: implications for epidemiological surveillance of leprosy cases and household contacts
BACKGROUND There is a lack of straightforward tests for field application and known biomarkers for predicting leprosy progression in infected individuals. OBJECTIVE The aim was to analyse the response to infection by Mycobacterium leprae based on the reactivity of specific antigens: natural disaccharide linked to human serum albumin via an octyl (NDOHSA)
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-09
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23. Fatores associados à capacidade funcional de idosos com hanseníase
RESUMO Objetivo: investigar a associação de fatores sociodemográficos e clínicos à capacidade funcional de idosos com hanseníase. Método: estudo transversal, analítico realizado em Fortaleza, Ceará, com 77 idosos com hanseníase acompanhados em serviço de referência, através de entrevista, consulta ao prontuário e aplicação do Índice de Kat
Rev. Bras. Enferm.. Publicado em: 2017-08
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24. Avaliação de concordância entre testes para diagnóstico da hanseníase
RESUMO Introdução: A hanseníase é uma doença infecciosa crônica causada pelo parasita intracelular Mycobacterium leprae. O diagnóstico é essencialmente clínico, com base em sintomas, exame da pele, nervos periféricos e história epidemiológica. Testes laboratoriais são realizados para complementar o resultado de diagnóstico clínico, ou mesmo s
J. Bras. Patol. Med. Lab.. Publicado em: 2017-04