Mutagenicity Tests
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. In vitro antifungal activity of Myracrodruon urundeuva Allemão against human vaginal Candida species
ABSTRACT Myracrodruon urundeuva is a plant native to Brazil, which is used by the indigenous population for the treatment of candidiasis. The aims of this study were to evaluate the antifungal activity of extract against human vaginal Candida species and evaluate the possible toxicological activities of M. urundeuva. Initially, ethanol extracts, ethyl acetat
An. Acad. Bras. Ciênc.. Publicado em: 24/07/2017
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2. The lipidome, genotoxicity, hematotoxicity and antioxidant properties of andiroba oil from the Brazilian Amazon
Abstract Andirobeira is an Amazonian tree, the seeds of which produce a commercially valuable oil that is used in folk medicine and in the cosmetic industry. Andiroba oil contains components with anti-inflammatory, cicatrizing and insect-repellant actions. However, virtually nothing is known of the safety of this oil for humans. The aim of this work was ther
Genet. Mol. Biol.. Publicado em: 13/05/2016
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3. Evaluation of mutagenicity and metabolism-mediated cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin from Paepalanthus latipes
A large number of quinones have been associated with antitumor, antibacterial, antimalarial, and antifungal activities. Results of previous studies of 5-methoxy-3,4-dehydroxanthomegnin, a naphthoquinone isolated from Paepalanthus latipes Silveira, Eriocaulaceae, revealed antitumor, antibacterial, immunomodulatory, and antioxidant activities. In this study, w
Rev. bras. farmacogn.. Publicado em: 2015-02
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4. Mutagênese ambiental: estabelecimento de valores de referência para manguezais da Baía de Ilha Grande / Environmental mutagenesis: establishment of reference valves for mangroves of Ilha Grande Bay
Environmental studies have shown that substances generated by anthropogenic processes can cause adverse effects by interfering with the ecosystem natural balance. Mangroves perform essential functions in biological cycles and are Permanent Protection Area in Brazil. Unfortunately, they are being degraded above its support limit, leading to a reduction of the
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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5. Avaliação do potencial de mutagenicidade e toxidade da lectina hipoglicemiante de folha de Bauhinia monandra (pata-de-vaca)
Medicinal plants have been used since antiquity to treat various human diseases. The leaves of Bauhinia monandra are widely used in Brazil as herbal remedies in the treatment of Diabetes Mellitus. From the leaves of B. monandra was purified a galactose-specific lectin, called BmoLL, which also showed a significant hypoglycemic capacity. Following the propose
Publicado em: 2009
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6. Avaliação do potencial genotóxico e cancerígeno do lodo de estação de tratamento de esgoto (LETE) em sistemas experimentais in vivo / In vivo evaluation of the carcinogenic potential of sewage sludge from a urban wastewater treatment plant in experimental systems
A rápida oxidação da matéria orgânica dos solos tropicais é mais uma evidência da grande vantagem do uso de biossólidos como condicionadores, capazes de melhorar as características físicas, químicas e biológicas do solo com grandes reflexos na produtividade agrícola. Portanto, o presente projeto objetivou averiguar o potencial genotóxico e canc
Publicado em: 2009
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7. Estudo das propriedades anticÃncer da piplartina / Study of anticancer properties of piplartine
A piplartina à um alcalÃide/amida conhecido encontrado em espÃcies do gÃnero Piper com propriedade citotÃxica interessante. Para avaliar o seu potencial antineoplÃsico, um estudo farmacolÃgico de suas propriedades anticÃncer foi realizado em vÃrios modelos biolÃgicos. A piplartina apresentou potente atividade citotÃxica em todas as linhagens tumor
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/06/2008
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8. Avaliação in vivo e in vitro da citotoxicidade, genotoxicidade e dos efeitos protetores de extratos de plantas do cerrado brasileiro
The use of plants for healing purposes is becoming increasingly popular, as soon as they are believed to be beneficial and free of side effects. However, most of information available on several medicinal herbs does not have any scientific supporting data and their use as medicaments is based simply on traditional folk. Among the plants used by the humanity
Publicado em: 2008
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9. Mutagênese induzida por flavonóides presentes do decocto das cascas da aroeira (Schinus terebinthifolius, Raddi)
The decoction of Brazilian pepper tree barks (Schinus terebinthifolius, Raddi), is used in medicine as wound healing and antiinflamatory. Once extracts from this plant are used for acceleration of scars process, it is important to study their mutagenic and genotoxic potential. In previous works in our laboratory, it was observed mutagenicity caused by the de
Publicado em: 2008
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10. Ecotoxicologia de um sistema florestal de eucalipto tratado com lodo de esgoto / Ecotoxicology of eucalyptus forest system treated with sewage sludge
The application of sewage sludge in forest systems quests the improvement of the production, favoring the physical, chemistries and biological characteristics of the soil and of the plants. However, the sludge can contain pathogen and, organic and inorganic toxics elements, and the effect of these pollutants in the soil and in the plant is still unknown. It
Publicado em: 2008
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11. AVALIAÇÃO DAS ATIVIDADES GENOTÓXICA E ANTIGENOTÓXICA DE DUGUETIA FURFURACEA EM BACTÉRIAS E CAMUNDONGOS / ASSESSMENT OF ACTIVITIES OF antigenotoxic genotoxic and Duguet furfuracea IN MICE AND BACTERIA
The plant Duguetia furfuracea (St. Hil.) Benth and Hook. f. (1862), belongs to the family Annonaceae, is popularly known as sofre‐do‐rim‐quem‐quer, araticum‐do‐cerrado and ata‐do‐mato. This plant occurres in several Brazilian states, as Amazonas, Bahia, Distrito Federal, Goiás, Minas Gerais, Mato Grosso, Mato
Publicado em: 2008
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12. Investigação de dioxinas, furanos, hidrocarbonetos policíclicos aromáticos no material particulado e gases emitidos por motores diesel / Investigation of dioxins, furans and polycyclic aromatic hydrocarbons in particulate material and gases emitted by diesel engines.
To investigate emission of chlorinated dioxins and furans (PCDD/Fs) and polycyclic aromatic hydrocarbons (PAHs) in heavy duty diesel engines, through the analysis of particulate material and gases in the exhaust.To verify mutagenicity of collected particulate material and gasesous sample extracts. Material and Methods: The engine emissions tests were done in
Publicado em: 2007