Muscle Spasticity
Mostrando 13-24 de 44 artigos, teses e dissertações.
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13. Comparison of dantrolene sodium and diazepam in the treatment of spasticity.
The effects of dantrolene sodium and diazepam were compared in a double crossover study of 42 patients with spasticity due to stable multiple sclerosis. Both drugs reduced the findings of spasticity, clonus, and hyperreflexia, and the complaints of muscle stiffness and cramping. Each drug had different side effects which suggest indications and contraindicat
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14. The limitations of the tendon jerk as a marker of pathological stretch reflex activity in human spasticity.
The motor disorders associated with human spasticity arise, partly from a pathological increase in the excitability of muscle stretch reflexes. In clinical practice, reflex excitability is commonly assessed by grading the reflex response to a blow delivered to the tendon of a muscle. This is a much simpler response than the complex patterns of activity which
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15. Radiofrequency cordotomy for the relief of spasticity in decerebrate cats1
The effectiveness of radiofrequency (RF) cordotomy of segmental motoneurone pools of the lumbosacral cord in reducing spasticity of decerebrate cats is evaluated. The need for a new form of therapy for clinical spasticity is based upon the limitations of contemporary methods, including surgical and pharmacological techniques. In man, spasticity of spinal ori
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16. Impaired regulation of force and firing pattern of single motor units in patients with spasticity.
Patients with spasticity were unable to maintain a constant force of the anterior tibial muscle. The force at maximal effort was reduced to less than 40% of normal, partly because motor units fired at a reduced rate even at high levels of contraction. Force and instantaneous frequency fluctuated slowly. The fast regulation of the firing rate, which character
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17. The effects of muscle vibration in spasticity, rigidity, and cerebellar disorders.
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18. Tonic vibration reflex in spasticity, Parkinson's disease, and normal subjects
The tonic vibration reflex (TVR) has been studied in the quadriceps and triceps surae muscles of 34 spastic, 15 Parkinsonism, and 10 normal subjects. The TVR of spasticity develops rapidly, reaching a plateau level within 2-4 sec of the onset of vibration. The tonic contraction was often preceded by a phasic spike which appeared to be a vibration-induced equ
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19. The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration.
In 25 patients with spasticity, pharmacokinetics and effects of dantrolene sodium were investigated after prolonged administration. A beneficial effect occurred in seven patients. The results were better on 100 mg daily than on a higher daily dose. An increase of the daily dose from 200 to 400 mg was not associated with higher blood levels. Many side effects
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20. Lasting reduction of severe spasticity after ending chronic treatment with intrathecal baclofen.
OBJECTIVE--To investigate whether the dose of intrathecal baclofen necessary for a sufficient reduction of muscle tone and spasms changes during treatment of severe spasticity. METHODS--A group of 27 patients received intrathecal baclofen for 61 (SD 18) months. RESULTS--Spasticity remained absent or strongly reduced after stopping the intrathecal baclofen in
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21. Treatment of shoulder pain in spastic hemiplegia by reducing spasticity of the subscapular muscle: a randomised, double blind, placebo controlled study of botulinum toxin A
BMJ Group.
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22. C0-contraction and stretch reflexes in spasticity during treatment with baclofen.
Surface electromyograms were recorded from the quadriceps and hamstring muscles of 11 spastic patients during cyclical flexion and extension movements of the knee. A potentiometer strapped to the knee recorded the angle of the joint, the output signal being displayed on an oscilloscope. The patient used this signal to track a sine wave target for 20 cycles.
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23. Self-regulation of spasm and spasticity in cerebral palsy.
Four young adult cerebral palsied subjects with a mixture of spasticity and athetosis attended an experimental reflex training program for three one-hour sessions each week over an 18 month period. During each session on-line measures of contraction level and tonic stretch reflex sensitivity from the biceps brachii muscle were shown to the subject on meter d
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24. Central effect of bladder filling and voiding.
In normal subjects and in patients with spasticity and/or urological complaints changes in somatic muscle reflexes associated with filling of the urinary bladder were observed. Two different patterns of reflex changes occurred. One pattern was associated with easy initiation of voiding: it consisted of increasing H and T reflexes and decreasing flexor reflex