Multidisciplinary Optimization
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Perspectives for cancer immunotherapy mediated by p19Arf plus interferon-beta gene transfer
While cancer immunotherapy has gained much deserved attention in recent years, many areas regarding the optimization of such modalities remain unexplored, including the development of novel approaches and the strategic combination of therapies that target multiple aspects of the cancer-immunity cycle. Our own work involves the use of gene transfer technology
Clinics. Publicado em: 06/09/2018
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2. Multidisciplinary Design Optimization of UAV Under Uncertainty
ABSTRACT: Uncertainty-based multidisciplinary design optimization considers probabilistic variables and parameters and provides an approach to account for sources of uncertainty in design optimization. The aim of this study was to apply a decoupling uncertainty-based multidisciplinary design optimization method without any dependence on probability mathemati
J. Aerosp. Technol. Manag.. Publicado em: 2017-06
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3. Multi-Disciplinary System Design Optimization of a Launch Vehicle Upper-Stage
ABSTRACT: The design method presented in this paper is related to the upper-stage system and its instrumentation, expedition and facilitation so as to transfer the satellite from the destination orbit to the target orbit. We used an integrated design method with a structure based on multidisciplinary system design optimization and developed a simple systemat
J. Aerosp. Technol. Manag.. Publicado em: 2017-03
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4. Application of Multidisciplinary Design Optimization on Advanced Configuration Aircraft
ABSTRACT: An optimization strategy is constructed to solve the aerodynamic and structural optimization problems in the conceptual design of double-swept flying wing aircraft. Aircraft preliminary aerodynamic and structural design optimization is typically based on the application of a deterministic approach of optimizing aerodynamic performance and structura
J. Aerosp. Technol. Manag.. Publicado em: 2017-03
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5. A New Approach to Multidisciplinary Design Optimization of Solid Propulsion System Including Heat Transfer and Ablative Cooling
ABSTRACT: The optimum design of a solid propulsion system consists of optimization of various disciplines including structure, aerothermodynamics, heat transfer, and grain geometry. In this paper, an efficient model of every discipline has been developed, and a suitable framework is introduced for these hard-coupled disciplines. Hybrid optimization algorithm
J. Aerosp. Technol. Manag.. Publicado em: 2017-03
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6. A Stochastic Reliability Model for Application in a Multidisciplinary Optimization of a Low Pressure Turbine Blade Made of Titanium Aluminide
Abstract Currently, there are a lot of research activities dealing with gamma titanium aluminide (γ-TiAl) alloys as new materials for low pressure turbine (LPT) blades. Even though the scatter in mechanical properties of such intermetallic alloys is more distinctive as in conventional metallic alloys, stochastic investigations on γ -TiAl alloys are very ra
Lat. Am. j. solids struct.. Publicado em: 2016-12
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7. A Multidisciplinary Design Optimization Tool for Spacecraft Equipment Layout Conception
ABSTRACT: One issue the design team has to face in the process of building a new spacecraft, is to define its mechanical and electrical architecture. The choice of where to place the spacecraft´s electronic equipment is a complex task, since it involves simultaneously many factors, such as the spacecraft's required position of center of mass, moments of ine
J. Aerosp. Technol. Manag.. Publicado em: 2014-12
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8. Theoretical Optimal Trajectories for Reducing the Environmental Impact of Commercial Aircraft Operations
ABSTRACT: This work describes initial results obtained from an ongoing research involving the development of optimization algorithms which are capable of performing multi-disciplinary aircraft trajectory optimization processes. A short description of both the rationale behind the initial selection of a suitable optimization technique and the status of the op
J. Aerosp. Technol. Manag.. Publicado em: 2014-03
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9. An Airplane Calculator Featuring a High- Fidelity Methodology for Tailplane Sizing
ABSTRACT: The present work is concerned with the accurate modeling of transport airplanes. This is of primary importance to reduce aircraft development risks and because multi-disciplinary design and optimization (MDO) frameworks require an accurate airplane modeling to carry out realistic optimization tasks. However, most of them still make use of tail volu
J. Aerosp. Technol. Manag.. Publicado em: 2013-12
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10. Kick Solid Rocket Motor Multidisciplinary Design Optimization Using Genetic Algorithm
ABSTRACT: In this paper, a multidisciplinary design optimization (MDO) approach of a solid propellant kick rocket motor is considered. A genetic algorithm optimization method has been used. The optimized kick solid rocket motor (KSRM) is capable of delivering a small satellite of 200 kg to a circular low earth orbit (LEO) of 600 km altitude. The KSRM should
J. Aerosp. Technol. Manag.. Publicado em: 2013-09
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11. Optimal Design of a High-Altitude Solar-Powered Unmanned Airplane
ABSTRACT: This paper describes a multi-disciplinary design and optimization framework tailored for the conceptual development of high-altitude solar-powered unmanned aerial vehicles. The aircraft baseline configuration that the framework is able to handle is very similar to that of Zephyr, which is developed by the UK based company QinetiQ. The disciplines o
J. Aerosp. Technol. Manag.. Publicado em: 2013-09
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12. Multidisciplinary Design Optimization of Sounding Rocket Fins Shape Using a Tool Called MDO-SONDA
Abstract: Multidisciplinary design optimization is a promising field in aerospace engineering. However, advances in this field have not been applied yet to improve Brazilian sounding rockets, such as the VS-40. Therefore, to give a perspective of the multidisciplinary design optimization in this context, this work presented a case study of this rocket, which
J. Aerosp. Technol. Manag.. Publicado em: 2012-12