Monomeric Proteins
Mostrando 1-12 de 430 artigos, teses e dissertações.
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1. [RETRACTED ARTICLE] Ginsenoside Rd inhibits IL-1β-induced inflammation and degradation of intervertebral disc chondrocytes by increasing IL1RAP ubiquitination
Many compounds of ginsenosides show anti-inflammatory properties. However, their anti-inflammatory effects in intervertebral chondrocytes in the presence of inflammatory factors have never been shown. Increased levels of pro-inflammatory cytokines are generally associated with the degradation and death of chondrocytes; therefore, finding an effective and non
Braz J Med Biol Res. Publicado em: 12/08/2019
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2. Sustainable Management of Keratin Waste Biomass: Applications and Future Perspectives
Keratin is a durable, fibrous protein which is mainly present in higher vertebrates (mammals, birds and reptiles) and humans epithelial cells. Food industry especially the meat market, slaughter house and wool industry produces million of tons of keratin containing biomass. These industries are constantly growing and the major producers include USA, Brazil a
Braz. arch. biol. technol.. Publicado em: 29/04/2016
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3. Aspectos termodinâmicos e bases moleculares na interação de proteínas monoméricas com agentes desnaturantes e alta pressão hidrostática / Thermodynamic aspects and molecular basis of monomeric proteins interaction with desnaturants and high hydrostatic pressure
Ureia desnatura proteínas em diferentes concentrações, dependendo das condições experimentais e da proteína. A proteína monomérica soro albumina bovina (BSA) foi o principal modelo de investigação na presença de concentrações subdesnaturantes de ureia com base no modelo de equilíbrio de dois estados. A desnaturação induzida por alta pressão
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2011
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4. Estudos funcionais da proteína reguladora humana Ki-1/57 e seus parceiros de interação / Functional studies of the human regulatory protein Ki-1/57 and its interaction partners
The protein Ki-1/57 was discovered through cross reactivity of the monoclonal antibody Ki-1 in cells of Hodgkin lymphoma. Previously studies demonstrated that Ki-1/57 interacts with RACK-1 protein, undergoes phosphorylation by PKCs and methylation by PRMT1, an arginine methyltransferase that modulates several RNA binding proteins. Studies have shown that Ki-
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/07/2011
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5. Structural studies of the proteins Q4DV70 from Trypanosoma cruzi and mesothelin from Homo sapiens / Estudos estruturais das proteinas Q4DV70 de Trypanosoma cruzi e mesotelina de Homo sapiens
In this work we carried out studies with two proteins, Q4DV70 from Trypanosoma cruzi and mesothelin from Homo sapiens. The aim was to help the understanding of the function of these proteins which possibly are important to Chagas disease and cancer, respectively. Q4DV70 protein was annotated in T. cruzi genome as a conserved hypothetical protein. In our stud
Publicado em: 2009
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6. Caracterização de uma aldo-ceto redutase relacionada a patogenicidade de Xylella fastidiosa / Characterization of a pathogenicity related Aldo-keto reductase from Xylella fastidiosa
The Xylella fastidiosa genome program generated a large number of gene sequences that belong to pathogenicity, virulence and adaptation categories from this important plant pathogen. One of these genes (XF 1729) was described in the genome annotation as being a phenylacetaldehyde dehydrogenase. However, the XF 1729 primary sequence analysis showed similariti
Publicado em: 2007
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7. Comparative study of the aminopeptidases purified from liver of patients with normal and altered serum aminotransferases levels. / Estudo comparativo entre as aminopeptidases purificadas de fígado de pacientes com as aminotransferases séricas normais e alteradas.
Enzymes like aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are released by the liver during several pathologies and have been used in laboratory tests to evaluate hepatic damage. Aminopeptidases, enzymes that hydrolyze peptide bonds in N-terminal amino acids of proteins, are important in protein metabolism and might have altered activit
Publicado em: 2006
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8. Role of protein present in the ink released by-the-sea slug Aplysia dactylomela Rang in 1828 in defense mechanisms of the animal / Papel de proteínas presentes na tinta liberada pela lesma-do-mar Aplysia dactylomela Rang 1828 nos mecanismos de defesa do animal
The marine gastropod Aplysia dactylomela is known to release a purple ink when it is plagued. How has no external structure of protection, it is believed that secretion, rich in biologically active substances, participate in the chemical defense of the animal. The ink is composed of pigments, proteins and low molecular weight substances. The pigments of ink
Publicado em: 2005
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9. Ethylene Regulates Monomeric GTP-Binding Protein Gene Expression and Activity in Arabidopsis1
Ethylene rapidly and transiently up-regulates the activity of several monomeric GTP-binding proteins (monomeric G proteins) in leaves of Arabidopsis as determined by two-dimensional gel electrophoresis and autoradiographic analyses. The activation is suppressed by the receptor-directed inhibitor 1-methylcyclopropene. In the etr1-1 mutant, constitutive activi
American Society of Plant Biologists.
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10. Ethylene Rapidly Up-Regulates the Activities of Both Monomeric GTP-Binding Proteins and Protein Kinase(s) in Epicotyls of Pea1
It is demonstrated that, in etiolated pea (Pisum sativum) epicotyls, ethylene affects the activation of both monomeric GTP-binding proteins (monomeric G-proteins) and protein kinases. For monomeric G-proteins, the effect may be a rapid (2 min) and bimodal up-regulation, a transiently unimodal activation, or a transient down-regulation. Pretreatment with 1-me
American Society of Plant Biologists.
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11. Surface-localized glycine transporters 1 and 2 function as monomeric proteins in Xenopus oocytes
Na+/Cl−-dependent neurotransmitter transporters form a superfamily of transmembrane proteins that share 12 membrane-spanning regions. To gain information about the quaternary structure of these transporter proteins, we heterologously expressed the glial glycine transporter GlyT1 and its neuronal homolog GlyT2 in Xenopus oocytes. By using metabolic lab
The National Academy of Sciences.
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12. Purification and Functional Reconstitution of Monomeric μ-Opioid Receptors: ALLOSTERIC MODULATION OF AGONIST BINDING BY Gi2*
Despite extensive characterization of the μ-opioid receptor (MOR), the biochemical properties of the isolated receptor remain unclear. In light of recent reports, we proposed that the monomeric form of MOR can activate G proteins and be subject to allosteric regulation. A μ-opioid receptor fused to yellow fluorescent protein (YMOR) was constructed and expr
American Society for Biochemistry and Molecular Biology.