Monoamines
Mostrando 13-24 de 45 artigos, teses e dissertações.
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13. Effects of chronic ethanol treatment on monoamine levels in rat hippocampus and striatum
We studied the effects of ethanol on concentrations of noradrenaline (NE), dopamine (DA) and serotonin (5-HT) and their metabolites in rat hippocampus and striatum. Ethanol (2 or 4 g/kg, po, from a 20% aqueous solution) was administered daily to male Wistar rats (4-13 per group) for 30 days and animals were sacrificed 30 min or 48 h after the last administra
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-12
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14. Monoamines in the pedal plexus of the land snail Megalobulimus oblongus (Gastropoda, Pulmonata)
In molluscs, the number of peripheral neurons far exceeds those found in the central nervous system. Although previous studies on the morphology of the peripheral nervous system exist, details of its organization remain unknown. Moreover, the foot of the terrestrial species has been studied less than that of the aquatic species. As this knowledge is essentia
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-07
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15. Behavioral, neurochemical, histopatological and biochemical alterations in rats treated with cocaine and ethanol singly or in association / Avaliação das alterações comportamentais, neuroquímicas, histopatológicas e bioquímicas em ratos tratados com cocaína e etanol isoladamente ou em associação
In the present work, behavioral, neurochemical (determination of monoamines and metabolites levels rat in striatum), histopatological and biochemical (lipoproteins and transaminases) alterations produced by cocaine, ethanol and the association of theses were analyzed. Females Wistar rats (180-200 g) were treated during 7 days with cocaine (Coc 10 and 20 mg/k
Publicado em: 2003
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16. Behavioral and neurochemical effects of melatonin in 6-OHDA-lesioned rats / Efeitos comportamentais e neuroquímicos da melatonina em ratos submetidos à lesão estriatal com 6-ohda
Os efeitos da melatonina (Mel) in vivo foram estudados no sistema dopaminérgico nigroestriatal de ratos, utilizando um modelo experimental da doença de Parkinson que consiste na injeção intraestriatal da neurotoxina 6-hidroxidopamina (6-OHDA). Ratos Wistar, machos (200-250g) foram submetidos a lesão unilateral com 6-OHDA, tratados com melatonina nas dos
Publicado em: 2002
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17. Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice
Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex, hippocampus, and cerebellum, compared with normal wild-type mice. Since monoamines in these areas are critically involved in a variety of behaviors, we examined lear
The National Academy of Sciences of the USA.
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18. MONOAMINES NOYAUX GRIS CENTRAUX ET SYNDROME DE PARKINSON
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19. Mice with Very Low Expression of the Vesicular Monoamine Transporter 2 Gene Survive into Adulthood: Potential Mouse Model for Parkinsonism
We have created a transgenic mouse with a hypomorphic allele of the vesicular monoamine transporter 2 (Vmat2) gene by gene targeting. These mice (KA1) have profound changes in monoamine metabolism and function and survive into adulthood. Specifically, these animals express very low levels of VMAT2, an endogenous protein which sequesters monoamines intracellu
American Society for Microbiology.
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20. ADVANCES IN BIOCHEMICAL PSYCHOPHARMACOLOGY: vol. 9—PHENOTHIAZINES AND STRUCTURALLY RELATED DRUGS; vol. 10—SEROTONIN—NEW VISTAS: HISTOCHEMISTRY AND PHARMACOLOGY; vol. 11—SEROTONIN—NEW VISTAS: BIOCHEMISTRY AND BEHAVIORAL AND CLINICAL STUDIES; vol. 12—NEUROPSYCHOPHARMACOLOGY OF MONOAMINES AND THEIR REGULATORY ENZYMES
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21. Parkinson disease: A new link between monoamine oxidase and mitochondrial electron flow
Two factors that contribute to the progression of Parkinson disease are a brain defect in mitochondrial respiration and the generation of hydrogen peroxide (H2O2) by monoamine oxidase (MAO). Here we show that the two are linked. Metabolism of the neurotransmitter dopamine, or other monoamines (benzylamine, tyramine), by intact rat brain mitochondria sup
The National Academy of Sciences of the USA.
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22. Influence of cerebral embolism on brain monoamines
In baboons the right cerebral hemisphere was embolised by a shower of microemboli, immediately followed by one large embolus designed to occlude the middle cerebral artery (MCA). One hour after embolism a significant, though small, reduction in blood flow and oxygen consumption of the embolised hemisphere was recorded, at which time the animals were killed a
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23. Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system.
1. Superfusates taken from spinal cords of cats anaesthetized with chloralose and urethane were assayed for endogenous serotonin and noradrenaline by high-pressure liquid chromatography with electrochemical detection. 2. Stimulating the dorsolateral funiculus, caudal to a spinal transection, enhanced in a frequency-dependent manner the levels of monoamines i
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24. Limitedly selective action of a delta-agonistic leu-enkephalin on the transmission in spinal motor reflex pathways in cats.
1. The influence of the delta-opioid receptor agonist (D-Ser2)-leu-enkephalin (Thr6) (DSLET) on different spinal reflex pathways was investigated in anaemically decapitated, high spinal cats. Monosynaptic reflexes were tested to analyse excitatory and inhibitory flexor reflex afferent (FRA) pathways from nociceptive (from the skin of the central pad) and non