Modulator
Mostrando 13-24 de 715 artigos, teses e dissertações.
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13. Agonistic activity of tamoxifen, a selective estrogen-receptor modulator (SERM), on arthritic ovariectomized mice
Arthritis is positively associated with the decline of sex hormones, especially estrogen. Tamoxifen (TMX) is a selective estrogen receptor modulator, possessing agonist or antagonistic activity in different tissues. Thus, the objective of this study was to investigate the effect of TMX on the zymosan-induced arthritis model. Female Swiss normal and ovariecto
Braz J Med Biol Res. Publicado em: 13/11/2017
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14. Dynamic Digital Holography for recording and reconstruction of 3D images using optoelectronic devices
Abstract In this work, we present the optical recording and reconstruction of dynamic 3D digital holograms using optoelectronic devices. Digital Holography technique allows recording and reconstruction of three-dimensional images of real objects, since a hologram presents both the intensity and phase information about the object. The experimental implementat
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2017-09
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15. Phytochemical study of Pilosocereus pachycladus and antibiotic-resistance modifying activity of syringaldehyde
ABSTRACT Pilosocereus pachycladus F. Ritter, Cactaceae, popularly known as "facheiro", is used as food and traditional medicine in Brazilian caatinga ecoregion. The plant is used to treat prostate inflammation and urinary infection. The present work reports the first secondary metabolites isolated from P. pachycladus. Therefore, the isolated compound 4-hydro
Rev. bras. farmacogn.. Publicado em: 2017-08
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16. Calcium homeostasis modulator 1 ( CALHM1 ) polymorphisms in cattle
ABSTRACT: The calcium homeostasis modulator 1 gene (CALHM1), which is located on chromosome 10 in humans and on chromosome 26 in cattle, is a transmembrane glycoprotein that controls the cytosolic calcium concentrations. Altered calcium homeostasis has been associated with several neurodegenerative disorders, including Alzheimer’s disease (AD). In a recent
Pesq. Vet. Bras.. Publicado em: 2017-06
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17. Does fire determine distinct floristic composition of two Cerrado savanna communities on different substrates?
ABSTRACT We surveyed two savanna sites, one on flat terrain with deep soil (DS), and the other on hilly terrain with rocky outcrops and shallow soil (RS), before and after an accidental fire. We found that the fire did not cause any significant changes in the species composition or diversity of either community, and did not result in floristic homogenization
Acta Bot. Bras.. Publicado em: 2017-06
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18. An Analytical Solution for Fiber Optic Links with Photonic-Assisted Millimeter Wave Upconversion Due to MZM Nonlinearities
Abstract Photonic-assisted technique employed in the generation of stable and high-purity signals in the millimeter wave band has been investigated using dual-parallel Mach-Zehnder modulator. Indeed, this type of generation performs a high order RF multiplier, whose operation principle steams out from the nonlinear characteristic of the external modulators.
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2017-03
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19. Trichotillomania: a case report with clinical and dermatoscopic differential diagnosis with alopecia areata
ABSTRACT Trichotillomania is a psychodermatologic disorder characterized by uncontrollable urge to pull one's own hair. Differential diagnoses include the most common forms of alopecia such as alopecia areata. It is usually associated with depression and obsessive-compulsive disorder. Trichotillomania treatment standardization is a gap in the medical literat
An. Bras. Dermatol.. Publicado em: 2017-02
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20. Allosteric interactions between receptor site 3 and 4 of voltage-gated sodium channels: a novel perspective for the underlying mechanism of scorpion sting-induced pain
AbstractBackground BmK I, a site-3-specific modulator of voltage-gated sodium channels (VGSCs), causes pain and hyperalgesia in rats, while BmK IT2, a site-4-specific modulator of VGSCs, suppresses pain-related responses. A stronger pain-related effect has been previously attributed to Buthus martensi Karsch (BmK) venom, which points out the joint pharmacolo
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 10/11/2015
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21. Steroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation
OBJECTIVE: To analyze steroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation. METHODS: Thirty-two virgin adult female rats were randomized to two groups as follows: the control group GI received vehicle and the experimental group GII received melatonin supplementation (10 µg/night per animal) for 60 consecutive days.
Clinics. Publicado em: 2015-02
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22. Frequency of the allelic variant c.1150T > C in exon 10 of the fibroblast growth factor receptor 3 (FGFR3) gene is not increased in patients with pathogenic mutations and related chondrodysplasia phenotypes
Mutations in the FGFR3 gene cause the phenotypic spectrum of FGFR3 chondrodysplasias ranging from lethal forms to the milder phenotype seen in hypochondroplasia (Hch). The p.N540K mutation in the FGFR3 gene occurs in ~70% of individuals with Hch, and nearly 30% of individuals with the Hch phenotype have no mutations in the FGFR3, which suggests genetic heter
Genet. Mol. Biol.. Publicado em: 21/10/2014
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23. Tratamento de aneurisma de aorta sacular justarrenal com Multilayer Flow Modulator: relato do primeiro caso realizado em Hospital Público no Brasil
O tratamento endovascular de aneurismas de aorta abdominal (AAA), envolvendo a saída das artérias renais e viscerais, constitui ainda um importante desafio. Diversas técnicas foram desenvolvidas ao longo do tempo para contornar as dificuldades oferecidas por esta situação, destacando-se as endopróteses fenestradas ou ramificadas, as técnicas envolvend
J. vasc. bras.. Publicado em: 2014-09
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24. Mannose-binding lectin 2 (MBL2) gene polymorphisms do not influence frequency of infections in chronic lymphocytic leukemia patients
Background: Infectious complications represent the main cause of morbidity and mortality in chronic lymphocytic leukemia. It has been reported that polymorphisms of the mannosebinding lectin 2 (MBL2) genes are correlated with MBL protein serum levels and, consequently, are associated with the development of infectious diseases. Objective: The purpose o
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-01