Microglobulin
Mostrando 1-12 de 458 artigos, teses e dissertações.
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1. Evaluation of Reference Genes for Quantitative PCR in Four Tissues from Rabbits with Hypercholesterolaemia
Abstract Rabbit with hypercholesterolaemia is an important model for studying cholesterol metabolism disease. This study aimed to evaluate the expression stability of nine reference genes for quantitative PCR (qPCR) analysis in adrenal gland, liver, spleen, and kidney tissue from rabbits with hypercholesterolaemia. In total, 30 male Harbin Large White (HLW)
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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2. Clinical and epidemiological profile of patients with early stage mycosis fungoides
Abstract: Background: Mycosis fungoides is the most common form of primary cutaneous lymphoma, with an indolent, slowly progressive course and 88% five-year survival rate. The diagnosis is challenging, especially in the early stages, and usually relies on a good clinical-histopathological correlation. Objective: The aim was to establish the clinical and ep
An. Bras. Dermatol.. Publicado em: 2018-08
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3. Urine alpha1-microglobulin is a better marker for early tubular dysfunction than beta2-microglobulin among tenofovir-exposed human immunodeficiency virus-infected men who have sex with men
Objectives: Men who have sex with men are at risk of tenofovir nephrotoxicity due to its wide use in both treatment and prophylaxis for human immunodeficiency virus infection, but little is known about the urinary biomarkers of early renal dysfunction in this population. This study aims to identify useful biomarkers of early renal dysfunction among human im
Braz J Infect Dis. Publicado em: 2015-08
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4. Validation of reference genes for RT-qPCR analysis of CYP4T expression in crucian carp
Reference genes are commonly used for normalization of target gene expression during RT-qPCR analysis. However, no housekeeping genes or reference genes have been identified to be stable across different tissue types or under different experimental conditions. To identify the most suitable reference genes for RT-qPCR analysis of target gene expression in the
Genet. Mol. Biol.. Publicado em: 2014-09
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5. Determination of urine tumor necrosis factor, IL-6, IL-8, and serum IL-6 in patients with hemorrhagic fever with renal syndrome
OBJECTIVE: The aim of this study was to explore the role of cytokines in the pathogenesis of hemorrhagic fever with renal syndrome (HFRS). METHODS: Double-antibody sandwich ELISA was used to determine serum interleukin (IL)-6, urine tumor necrosis factor (TNF), IL-6, and IL-8 levels in 56 patients with HFRS. RESULTS: Serum IL-6, urine TNF, IL-6, and IL-8 con
Braz J Infect Dis. Publicado em: 2012-12
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6. Chronic hepatitis virus infection in patients with multiple myeloma: clinical characteristics and outcomes
OBJECTIVES: Cytotoxic agents and steroids are used to treat lymphoid malignancies, but these compounds may exacerbate chronic viral hepatitis. For patients with multiple myeloma, the impact of preexisting hepatitis virus infection is unclear. The aim of this study is to explore the characteristics and outcomes of myeloma patients with chronic hepatitis virus
Clinics. Publicado em: 2011
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7. The 5 alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals
The aim of the present study was to determine the expression of the genes for type 1 (SDR5A1) and type 2 (SDR5A2) 5α-reductase isoenzymes in scalp hairs plucked from 33 hirsute patients (20 with polycystic ovary syndrome and 13 with idiopathic hirsutism) and compare it with that of 10 men and 15 normal women. SDR5A1 and SDR5A2 expression was estimated by RT
Publicado em: 2010
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8. Proximal tubular dysfunction as an indicator of chronic graft dysfunction
New strategies are being devised to limit the impact of renal sclerosis on graft function. Individualization of immunosuppression, specifically the interruption of calcineurin-inhibitors has been tried in order to promote better graft survival once chronic graft dysfunction has been established. However, the long-term impact of these approaches is still not
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-03
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9. Influence of ovarian hormones deprivation on gene expression in the lower urinary tract of rats
OBJECTIVE: Identify the influence of ovarian hormone deprivation in expression genes on the lower urinary tract of rats. MATERIALS AND METHODS: This study deals with gene screening on lower urinary tract of rats. Fifty isogenic rats divided in two groups of twenty-five animals have their lower urinary tract surgically removed: group I, ovariectomized rats 30
International braz j urol. Publicado em: 2007-08
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10. Expressão do MHC classe I e sua Influencia sobre as alterações sinaptologicas em camundongos de diferentes linhagens isogenicas, 1 e 3 semanas após a transecção do nervo ciatico / Expression of MHC class I influences synaptological changes in different isogenic mice strains, 1 and 3 weeks after sciatic nerve transection
o estabelecimento das redes nervosas que compõem o Sistema Nervoso Central (SNC) é um processo imensamente complexo dependente, não somente da formação de novos pontos de comunicação, as sinapses, mas também da eliminação de sinapses supranumerárias ou incorretas durante o desenvolvimento. Recentemente, foi descrito um mecanismo demonstrando que a
Publicado em: 2007
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11. Estudo da expressão de Antígenos Aberrantes em plasmócitos de portadores de Mieloma Múltiplo através de Citometria de Fluxo Mul-tiparamétrica / Detection of aberrant antigens in multiple myeloma cells by multiparametric flow cytometry.
The aims of this study were to determine aberrant antigens (AA) in MM cells and to evaluate their prognostic value and frequency. Methods : bone marrow plasma cells of an homogeneous cohort of 30 newly diagnosed patients with MM were studied. As normal control, bone marrow plasma cells from 4 healthy marrow do-nors were also evaluated. Surface and cytoplasmi
Publicado em: 2006
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12. Differential expression of the KLK2 and KLK3 genes in peripheral blood and tissues of patients with prostate cancer
We used the multiplex semi-quantitative reverse-transcriptase PCR (RT-PCR) to investigate kallikrein 2 and 3 (KLK2 and KLK3) mRNA levels in prostate tissue from 42 prostate cancer patients, 33 of whom were also assessed for peripheral blood KLK2 expression by qualitative semi-nested RT-PCR. We found that KLK2 was an important tissue biomarker for distinguish
Genetics and Molecular Biology. Publicado em: 2006