Microdialysis
Mostrando 13-24 de 136 artigos, teses e dissertações.
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13. Avaliação do efeito de um extrato lipofílico de Hypericum caprifoliatum Cham.& Schltdl sobre os níveis cerebrais de dopamina e seus metabólitos através de microdiálise cerebral em ratos conscientes / Evaluation of the effect of Hypericum caprifoliatum Cham. & Schltdl lipophilic extract on the extracellular levels of dopamine and its metabolites by cerebral microdialysis in freely moving rats
OBJETIVO: Desenvolver e validar a técnica de CLAE-DE para o doseamento de dopamina (DA), ácido diidrofenilacético (DOPAC), ácido homovanílico (HVA) e 3-metoxitiramina (3-MT); validar a técnica de microdiálise (MD) cerebral em animais conscientes e avaliar o efeito do tratamento agudo com um extrato lipofílico das partes aéreas de Hypericum caprifoli
Publicado em: 2007
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14. Efeito anticatabólico dos derivados de xantina no metabolismo de proteínas em músculos esqueléticos de ratos sépticos: um estudo de microdiálise.
Objetivo: investigar o efeito anticatabólico dos derivados de xantinas no metabolismo de proteínas de ratos sépticos utilizando a técnica de microdiálise. Materiais e métodos: Ratos machos Wistar (~250g) foram anestesiados com tiopental (50mg/Kg, i.p.) e mantidos em mesa cirúrgica aquecida (37C). A sepse foi induzida pela ligadura e punção do ceco (
Publicado em: 2006
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15. A brain microdialysis study on 5-HT release in freely moving rat lines selectively bred for differential 5-HT1A receptor function
Breeding for high and low hypothermic responses to systemic administration of a serotonin1A (5-HT1A) receptor agonist (8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT) has resulted in high DPAT-sensitive (HDS) and low DPAT-sensitive (LDS) lines of rats, respectively. These lines also differ in several behavioral measures associated with stress. In the pres
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02
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16. Determining heat and mechanical pain threshold in inflamed skin of human subjects
In a previous article in the Journal of Visualized Experiments we have demonstrated skin microdialysis techniques for the collection of tissue-specific nociceptive and inflammatory biochemicals in humans. In this article we will show pain-testing paradigms that are often used in tandem with microdialysis procedures. Combining pain tests with microdialysis p
MyJove Corporation.
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17. Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis.
The underlying mechanisms of neuronal dysfunction in head injury are multifactorial and not fully understood. Recent experimental evidence indicates that excitatory amino acids--for example, glutamate--may play a key part in secondary neuronal damage after head injury. A patient with severe head trauma was monitored for extracellular amino acids by intracere
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18. Penetration of Meropenem into Pneumonic Human Lung Tissue as Measured by In Vivo Microdialysis
Until recently, information on antibiotic pharmacokinetic properties in infected human lung tissue was limited. We therefore studied a microdialysis-based approach for measurement of the penetration of meropenem into the extracellular space fluid of human pneumonic lung parenchyma. The lung penetration of meropenem was determined for seven patients with pneu
American Society for Microbiology.
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19. In situ microdialysis in bone tissue. Stimulation of prostaglandin E2 release by weight-bearing mechanical loading.
In this study we describe, to our knowledge, the first experiment using the microdialysis technique for studying the release of prostaglandin E2 (PGE2) in the proximal tibia metaphysis secondary to mechanical loading. Nine healthy females, six in the loading group and three controls, mean age 34+/-2 (years+/-SEM), participated. A standard microdialysis cathe
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20. A simple device for microdialysis.
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21. Discovering New Bioactive Neuropeptides in the Striatum Secretome Using in Vivo Microdialysis and Versatile Proteomics S⃞
The striatum, a major component of the brain basal nuclei, is central for planning and executing voluntary movements and undergoes lesions in neurodegenerative disorders such as Huntington disease. To perform highly integrated tasks, the striatum relies on a complex network of communication within and between brain regions with a key role devoted to secreted
American Society for Biochemistry and Molecular Biology.
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22. Want to exchange your virus? Try microdialysis and Raman.
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23. Clinical evaluation of vasospasm in subarachnoid haemorrhage by in vivo microdialysis.
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24. Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans.
The calculation of pharmacokinetic/pharmacodynamic surrogates from concentrations in serum has been shown to yield important information for the evaluation of antibiotic regimens. Calculations based on concentrations in serum, however, may not necessarily be appropriate for peripheral-compartment infections. The aim of the present study was to apply the micr