Mice Inbred Balb C
Mostrando 1-12 de 179 artigos, teses e dissertações.
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1. Expression and possible functional role of galectin-3 in the / Expressão e possível papel funcional da galectina-3 no timo de camundongos diabéticos não-obesos (NOD)
Galectin-3 belongs to a family of endogenous lectins which bind to -galactosides presented on the cell surface and extracellular matrix glycoproteins. It is involved in multiple biological functions such as cell growth, adhesion, proliferation and apoptosis. Moreover, galectin-3 is found in several tissues and organs, being highly conserved among animal spec
Publicado em: 2010
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2. Participação do fator inibidor da migração de macrófagos (MIF) no processo inflamatório pulmonar induzido por sílica em camundongos / Involvement of inhibitory factor macrophage migration (MIF) in pulmonary inflammation induced by silica in mice
A silicose é a pneumoconiose de maior prevalência no Brasil e resulta da exposição às partículas de sílica cristalina, sendo caracterizada por infiltrado inflamatório, deposição de colágeno e formação de granulomas, em um contexto dependente de uma gama de mediadores. O fator inibidor da migração de macrófagos (MIF) é uma citocina pró-infla
Publicado em: 2009
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3. The bone marrow micronucleus test and metronidazole genotoxicity in different strains of mice (Mus musculus)
The mouse (Mus musculus) bone marrow micronucleus test was carried out using 24 outbred National Institutes of Health (NIH) mice, 24 inbred Swiss Webster (CFW) mice and 20 inbred Bagg albino/color locus Jackson (BALB/cJ) mice. The mice in the experimental group (n = 32) were injected intraperitoneally with 133 mg kg-1 of metronidazole parenteral solution and
Genetics and Molecular Biology. Publicado em: 2007
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4. Effect of GM1 ganglioside in the sciatic nerves of the NOD (non obse diabetic) / Estudo do efeito do gangliosideo GM1 sobre os nervos perifericos do camundongo NOD (Non Obese Diabetic)
A linhagem de camundongos NOD (non obese diabetic) desenvolve espontaneamente diabetes mellitus tipo 1 (DM-1) com marcante similaridade ao observado em humanos, que se estabelece entre 12ª e 24ª semana de vida. Os gangliosideos são glicoesfingolipídeos de membrana que contém ácido siálico em sua composição e estão presentes na maioria das células
Publicado em: 2007
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5. Effects of exposure to ambient level of particulate matter on the development of pulmonary emphysema / O efeito da exposição a níveis ambientais de material particulado no desenvolvimento do enfisema pulmonar em camundongos
A inalação de material particulado (PM) exerce um papel importante na exacerbação de doenças respiratórias, incluindo DPOC e asma, no entanto os efeitos específicos do PM no desenvolvimento do enfisema pulmonar são ainda pouco descritos na literatura. Neste estudo investigamos os efeitos da exposição crônica a níveis ambientais de PM no desenvolv
Publicado em: 2007
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6. Role of cytokines, NO, and H2O2 on the immunopathology of Leptospirosis in genetically selected mice
Immune response to leptospirosis is mainly humorally mediated, and involves opsonization of leptospires for phagocytosis by macrophages and neutrophils. However, some aspects are still unknown. For a more detailed analysis of the cellular immune response to leptospirosis infection, trials were carried out in order to determine the hydrogen peroxide and nitri
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2005-06
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7. Fibrose e outras lesÃes hepÃticas em camundongos isogÃnicos ("inbred") desnutridos e eutrÃficos, infectados com Schistosoma mansoni / Fibrosis and other hepatic lesions in undernourished and well-nourished inbred mice infected with
In chronic schistosomiasis mansoni, periovular granulomas and periportal fibrosis are the most important hepatic lesions, besides vascular changes that lead to hypertension within the portal venous system. Well-nourished Swiss outbred mice infected with Schistosoma mansoni develop lesions that mimick those found in advanced clinical forms of human intestinal
Publicado em: 2004
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8. Role of Genetic Resistance in Invasive Pneumococcal Infection: Identification and Study of Susceptibility and Resistance in Inbred Mouse Strains
From a panel of nine inbred mice strains intranasally infected with Streptococcus pneumoniae type 2 strain, BALB/c mice were resistant and CBA/Ca and SJL mice were susceptible to infection. Further investigation revealed that BALB/c mice were able to prevent proliferation of pneumococci in the lungs and blood, whereas CBA/Ca mice showed no bacterial clearanc
American Society for Microbiology.
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9. Association Between Fighting Behavior and Catecholamine Biosynthetic Enzyme Activity in Two Inbred Mouse Sublines
Levels of three adrenal catecholamine synthesizing enzymes and isolation-induced fighting behavior were studied in two related sublines of the Balb/c inbred mouse strain. Enzyme levels were twice as high in the adrenals of Balb/cJ mice as in those of the Balb/cN mice; heterozygous progeny were intermediate between their parents in the levels of the three enz
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10. Induction and expression of cell-mediated immune responses in inbred mice infected with Coccidioides immitis.
Comparisons of the course of coccidioidomycosis in two strains of inbred mice established that BALB/c mice are significantly more susceptible to pulmonary infection with Coccidioides immitis than are DBA/2 mice. The susceptibility of BALB/c mice does not reside in their inability to mount a delayed-type hypersensitivity response to C. immitis antigen. That i
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11. Host Defenses in Experimental Scrub Typhus: Genetics of Natural Resistance to Infection
Genetic resistance to lethal infection with Rickettsia tsutsugamushi was studied in over 30 inbred strains, inbred hybrids, and outbred stocks of mice. Inbred mice infected intraperitoneally with the Gilliam strain of R. tsutsugamushi showed three patterns of response: susceptible (A/HeJ, C3H/HeDub, C3H/HeJ, C3H/HeN, C3H/St, CBA/J, DBA/1J, DBA/2J, and SJL/J)
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12. Inbred mouse strains differ in resistance to lethal Coccidioides immitis infection.
Inbred strains of mice were infected intraperitoneally with Coccidioides immitis, and the mean lethal dose was determined after 28 days. DBA/2N mice had a mean lethal dose of greater than 10(5) arthroconidia, whereas BALB/cAnN, C57BL/6N, and C57L/J mice had a mean lethal dose of less than or equal to 10(3). Since both BALB/c and DBA/2 mice are the H-2d haplo