Metoxiamina
Mostrando 1-1 de 1 artigos, teses e dissertações.
-
1. Assessment of cellular responses mediated by temozolomide combined with metoxiamina, an inhibitor of DNA repair, in glioblastoma cell lines. / Avaliação da resposta celular mediada pelo quimioterápico temozolomida associada ao inibidor do reparo do DNA metoxiamina em linhagens de glioblastoma.
Gliomas represent more than 70% of primary brain tumors. Even following an aggressive therapies, the mean survival rate of patients with these tumors is less than one year after diagnosis. Chemotherapy based on alkyklating agents, such as temozolomide (TMZ) has been reported to increase the survival rate. N7-metyl-G and N3-metyl-A adducts comprise more than
Publicado em: 2009