Methacholine
Mostrando 13-24 de 263 artigos, teses e dissertações.
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13. Health in early adulthood: the contribution of the 1978/79 Ribeirão Preto birth cohort
The increase in non-communicable chronic diseases of adults is due to demographic changes and changes in the risk factors related to physical activity, smoking habits and nutrition. We describe the methodology for the evaluation of persons at 23/25 years of age of a cohort of individuals born in Ribeirão Preto in 1978/79. We present their socioeconomic char
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-08
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14. Involvement of the bradykinin B1 receptor and the paradoxical effect of the nitric oxide in the allergic lung inflammation in mice / Envolvimento do receptor B1 da bradicinina e o efeito paradoxal do oxido nitrico na inflamação alergica pulmonar em camundongos
A asma é uma doença inflamatória crônica que envolve, simultaneamente, a participação de diversos tipos celulares, citocinas e mediadores inflamatórios. Apesar do grande número de estudos sobre o papel da bradicinina e do óxido nítrico (NO) na asma, vários aspectos não foram abordados e outros são controversos. Os objetivos deste trabalho foram,
Publicado em: 2006
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15. Effect of salbutamol on pulmonary responsiveness in chronic pulmonary allergic inflammation in guinea pigs
Beta-2-agonists have been widely used by asthmatic subjects to relieve their obstructive symptoms. However, there are reports that continuous use could lead to loss of bronchial protection and exacerbation of asthma symptoms. We evaluated the effect of two regimens of salbutamol administration (twice and five times a week) in a model of chronic airway inflam
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-05
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16. Bronchial hyperresponsiveness and analysis of induced sputum cells in Crohn's disease
With the aim of investigating the presence of latent inflammatory process in the lungs of patients with Crohn's disease, 15 patients with Crohn's disease were evaluated by spirometry, the methacholine challenge test, induced sputum, and skin tests for inhaled antigens. Serum IgE, erythrocyte sedimentation rate and hematocrit were also determined. The patient
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-02
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17. Efeitos da suplementação oral de magnesio em escolares e adolescentes com asma atopica moderada
Magnesium is an important cation in our body and it has been used intravenously for the treatment of acute asthma. However, there is on1y one study with its oral use for chronic asthma, in adults. The objective of this study was to compare the effects of magnesium oral supplementation on moderate atopic asthma in children and adolescents. lt was a prospectiv
Publicado em: 2003
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18. Reflex control of arterial pressure and heart rate in short-term streptozotocin diabetic rats
Impaired baroreflex sensitivity in diabetes is well described and has been attributed to autonomic diabetic neuropathy. In the present study conducted on acute (10-20 days) streptozotocin (STZ)-induced diabetic rats we examined: 1) cardiac baroreflex sensitivity, assessed by the slope of the linear regression between phenylephrine- or sodium nitroprusside-in
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-07
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19. Envolvimento do oxido nitrico nas respostas edematogenicas e espasmogenicas induzidas pela bradicinina e histamina
No synthesized from L-arginine, is responsible for various biological effects including oedema formation by plasma protein extravasation (PPE). PPE responses have been measured using local accumulation of intravenously injected 1251-human serum albumin and blood flow by means of a multiple 133 Xenon (Xe) technique in guinea pig skin. L-NAME reduced responses
Publicado em: 1995
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20. Increased responsiveness to methacholine and histamine after challenge with ultrasonically nebulised water in asthmatic subjects.
Responsiveness to inhaled methacholine was compared before and 40-60 minutes after a challenge with ultrasonically nebulised water (UNH2O) in 16 asthmatic patients. The sensitivity to methacholine increased after UNH2O challenge (p less than 0.001). The mean dose of methacholine producing a 20% fall in forced expiratory volume in one second was 0.4 (95% conf
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21. Effect of theophylline and enprofylline on bronchial hyperresponsiveness.
The effect of increasing intravenous doses of theophylline and enprofylline, a new xanthine derivative, on bronchial responsiveness to methacholine was studied in eight asthmatic patients. Methacholine provocations were carried out on three days before and after increasing doses of theophylline, enprofylline, and placebo, a double blind study design being us
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22. Comparison of in vivo airway responsiveness and in vitro smooth muscle sensitivity to methacholine in man.
Airway responsiveness to methacholine varies between normal people and is increased in patients with asthma. The importance of airway smooth muscle sensitivity in determining in vivo responsiveness is unknown. We have examined this question by comparing in vivo airway responsiveness with in vitro airway smooth muscle sensitivity to methacholine in 10 patient
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23. Nasal response of rhinitic and non-rhinitic subjects to histamine and methacholine: a comparative study.
The nasal responses to provocation with histamine and methacholine were compared in 20 subjects with and 20 without rhinitis. Two variables were measured: nasal airways resistance and the development of rhinorrhoea. Histamine had a greater effect than methacholine in increasing nasal airways resistance while the converse was true for rhinorrhoea. Rhinitic su
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24. Differences in responsiveness to hyperventilation and methacholine in asthma and chronic bronchitis.
In a previous study on 27 patients with chronic bronchitis we found that only three developed bronchoconstriction in response to hyperventilation of cold, dry air despite an increased responsiveness to methacholine inhalation. We therefore investigated bronchial responsiveness to hyperventilation with cold, dry air and methacholine in 27 patients with stable