Metabolic Agent
Mostrando 1-12 de 162 artigos, teses e dissertações.
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1. Immunological deficiencies: more frequent than they seem to be
Abstract Objective: A review article was carried out, addressing the clinical and epidemiological characteristics of immune system deficiencies, which are associated with or predispose to recurrent infectious processes, autoimmune diseases, auto inflammatory diseases, or neoplasms, and which are classified as inborn errors of immunity (IEI) and secondary im
J. Pediatr. (Rio J.). Publicado em: 2021-04
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2. Influence of High Light Intensity and Nitrate Deprivation on Growth and Biochemical Composition of the Marine Microalgae Isochrysis galbana
Abstract Isochrysis galbana is a brown microalgae widely used as a feed for marine organism in aquaculture. The aim of present study is to investigate the growth, biochemical composition, fatty acid profile, photosynthetic parameters and antioxidant activity (radical scavenging activity) of Isochrysis galbana cells cultivated under different levels (sub-opti
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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3. Trypanosoma cruzi transcriptome during axenic epimastigote growth curve
BACKGROUND Trypanosoma cruzi is an important protozoan parasite and the causative agent of Chagas disease. A critical step in understanding T. cruzi biology is the study of cellular and molecular features exhibited during its growth curve. OBJECTIVES We aimed to acquire a global view of the gene expression profile of T. cruzi during epimastigote growth.
Mem. Inst. Oswaldo Cruz. Publicado em: 09/04/2018
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4. Both glucocentric and cardiocentric approaches are necessary for a resilient disease such as diabetes
Summary Diabetes mellitus (DM) is a complex disease that compromises almost all systems in the human organism. Independently of the intrinsic mechanisms, the source of all consequences of DM is hyperglycemia, a condition associated to intense metabolic changes that will lead to increased morbidity and mortality in the long term. Several different therapeutic
Rev. Assoc. Med. Bras.. Publicado em: 2018-03
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5. Challenging Mycobacterium tuberculosi s dormancy mechanisms and their immunodiagnostic potential
ABSTRACT Mycobacterium tuberculosis is the etiologic agent of tuberculosis, one of the world's greatest cause of morbidity and mortality due to infectious disease. Many evolutionary mechanisms have contributed to its high level of adaptation as a host pathogen. Prior to become dormant, a group of about 50 genes related to metabolic changes are transcribed by
Braz J Infect Dis. Publicado em: 2015-12
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6. Identification of the nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi
The intracellular parasite Trypanosoma cruzi is the aetiological agent of Chagas disease, a public health concern with an increasing incidence rate. This increase is due, among other reasons, to the parasite’s drug resistance mechanisms, which require nicotinamide adenine dinucleotide (NAD+). Furthermore, this molecule is involved in metabolic and intracel
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-11
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7. Protection against neurotoxicity by an autophagic mechanism
The objective of the present study was to investigate the effects of 3-n-butylphthalide (NBP) on a 1-methyl-4-phenylpyridinium (MPP+)-induced cellular model of Parkinson’s disease (PD) and to illustrate the potential mechanism of autophagy in this process. For this purpose, rat PC12 pheochromocytoma cells were treated with MPP+ (1 mM) for 24 h following pr
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-05
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8. Determinação de enxofre em amostras vegetais por oxidação via seca em meio alcalino com detecção espectrofométrica
The sulphur take an essential role in plants and it is one of the main nutrients in several metabolic processes. The dry ash oxidation, using alkaline oxidizers agent, is the simplest and most economical form for the oxidation of Organic S to sulfate in plants. The objective of this work is to propose a method for sulfur determination in plants samples using
Química Nova. Publicado em: 2011
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9. Induction of SCEs and DNA fragmentation in bovine peripheral lymphocytes by in vitro exposure to tolylfluanid-based fungicide
The potential for genotoxic and cytotoxic effects of tolylfluanid-based fungicide (50% active agent) was evaluated using sister chromatid exchange (SCE) and proliferation indices (PI) in cultured bovine peripheral lymphocytes. For the detection of possible genetic damage, DNA fragmentation assay was also applied. Bovine lymphocytes cultured for 72 h were tre
Genetics and Molecular Biology. Publicado em: 19/11/2010
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10. Effect of organic tomato ( Lycopersicon esculentum ) extract on the genotoxicity of doxorubicin in the Drosophila wing spot test
The consumption of organic tomatoes (ORTs) reduces the risk of harmful effects to humans and the environment caused by exposure to toxic agrochemicals. In this study, we used the somatic mutation and recombination test (SMART) of wing spots in Drosophila melanogaster to evaluate the genotoxicity of ORT and the effect of cotreatment with ORT on the genotox
Genetics and Molecular Biology. Publicado em: 17/01/2009
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11. Estudo da remoção e toxicidade dos pesticidas atrazina e oxifluorfem pela cianobactéria "Microcystis novacekii" em condições de cultivo.
Water contamination by pesticides due to anthropogenic activities has become a global concern in terms of environmental damage and public health. The cyanobacteria are microrganisms capable of growing in polluted environments and their potential as agents of bioremediation of contaminated environments is promising. This study aimed to evaluate the potential
Publicado em: 2009
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12. Efeito do maracujá (Passiflora incarnata) sobre a morfometria de hepatócitos da tilápia do Nilo (Oreochromis niloticus) / Effect of Passion fruit (Passiflora incarnata) on the hepatocytes morphometry of Nile tilapia (Oreochromis niloticus)
Effects of Passion fruit (Passiflora incarnata) dry extract administration on hepatocyte morphometry of juveniles Nile tilapias (Oreochromis niloticus) were investigated. Male isolated fish (86,50 ± 10,17 g) were daily fed (28 days) with extruded commercial ration (32% crude protein - 2% biomass) containing the extract diluted in sodium alginate in gr
Publicado em: 2008