Mesenteric Rings
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. Vasorelaxant activity and acute toxicity of the ethanolic extract of Zanthoxylum rhoifolium Lam leaves
The study evaluated the vasorelaxant effect induced by the ethanolic extract of the leaves of Zanthoxylum rhoifolium Lam (EEtOH-Zr/leaves). Wistar rats were treated with the leaf extract containing a single dose of 2,000 mg / kg, v.o. After 14 days, the animals were anesthetized for blood collection and subsequent analysis of the biochemical parameters; they
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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2. Myosin light chain kinase is necessary for post-shock mesenteric lymph drainage enhancement of vascular reactivity and calcium sensitivity in hemorrhagic-shocked rats
Vascular hyporeactivity is an important factor in irreversible shock, and post-shock mesenteric lymph (PSML) blockade improves vascular reactivity after hemorrhagic shock. This study explored the possible involvement of myosin light chain kinase (MLCK) in PSML-mediated vascular hyporeactivity and calcium desensitization. Rats were divided into sham (n=12), s
Braz J Med Biol Res. Publicado em: 30/07/2013
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3. Role of protein kinase G on the post-shock mesenteric lymph blockage ameliorating vascular calcium sensitivity
PURPOSE: To investigate the role of protein kinase G (PKG) in blocking post-shock mesenteric lymph (PSML) return ameliorating the calcium sensitivity in hemorrhagic shock rats. METHODS: Male Wistar rats were randomly divided into sham, shock, shock+ligation (shock plus mesenteric lymph duct ligation (MLDL)), shock+drainage (shock plus PSML drainage) groups.
Acta Cir. Bras.. Publicado em: 2013-07
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4. Participação dos canais para potássio nos efeitos cardiovasculares induzidos por um novo composto 1,3,4- oxadiazol. / Participation of potassium channels in cardiovascular effects induced by a novel compound 1,3,4-oxadiazole.
Os efeitos farmacológicos de OXDINH, um derivado 1,3,4-oxadiazol obtido por síntese orgânica, sobre o sistema cardiovascular e a participação dos canais para K+ nesta resposta, foram estudados em ratos usando técnicas combinadas in vivo e in vitro. Em anéis de artéria mesentérica superior isolada de rato, com endotélio funcional, OXDINH (10-10 10-4
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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5. Erythroxylum pungens elicits vasorelaxation by reducing intracellular calcium concentration in vascular smooth muscle cells of rats
The cardiovascular effects elicited by the ethanolic extract obtained from the roots of Erythroxylum pungens O.E. Schulz, Erythroxylaceae (EEEP) and the vasorelaxant effect induced by its main tropane alkaloid (pungencine) were investigated. In normotensive rats, administration of EEEP (1, 10, 30 and 60 mg/kg i.v., randomly) produced dose-dependent hypotensi
Revista Brasileira de Farmacognosia. Publicado em: 06/01/2012
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6. Pharmacological effects of the sesquiterpenic alcohol (-)-α-bisabolol in vascular and non-vascular smooth muscle preparations. / Efeitos farmacolÃgicos do Ãlcool sesquiterpÃnico (-)-α-bisabolol em preparaÃÃes isoladas de mÃsculo liso vasculares e nÃo-vasculares.
In this in vitro study the effects of the monocyclic sesquiterpene alcohol (-)-α-bisabolol on the contractile behavior of rat and mouse smooth muscle preparations were investigated. Under resting tonus, (-)-α-bisabolol relaxed duodenal smooth muscle preparations, whereas it showed biphasic effects in other smooth muscles, contracting endothelium-in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/10/2011
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7. Renal- and calcium-dependent vascular effects of Polybia paulista wasp venom
In the present study, the effects of Polybia paulista venom (PPV) on renal and vascular tissues were investigated. Isolated kidneys perfused with PPV (1 and 3 μg/mL) had increased perfusion pressure, renal vascular resistance, urinary flow, and glomerular filtration rate; and reduced sodium tubular transport. Histological evaluation demonstrated deposits of
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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8. Efeitos inibitÃrios da sertralina no sistema urinÃrio de ratos. / Inhibitory effects of sertraline on rat urinary system.
Sertraline, a drug belonging to the family of selective serotonin reuptake inhibitors, is used in antidepressant therapy, and has good tolerance with low incidence of side effects. Here we have characterized the pharmacological effects of sertraline on the pattern of voiding anesthetized rats, on the renal functional parameters of isolated rat kidney and on
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/11/2010
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9. Avaliação dos efeitos induzidos pelo 2-Nitrato-1, 3-Dibutoxipropano (NDBP) sobre o sistema cardiovascular de ratos normotensos - abordagens en vivo e in vitro
Organic nitrates are nitric oxide (NO) donors used in the treatment of cardiovascular diseases mimicking the role of endogenous NO. This study evaluated organic nitrates newly synthesized from glycerin, which cardiovascular actions had not yet been investigated. Therefore, the cardiovascular effects produced by organic nitrates derived from glycerin: 2-nitra
Publicado em: 2010
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10. EFEITOS DO TREINAMENTO RESISTIDO SOBRE AS ALTERAÇÕES NA REATIVIDADE VASCULAR DE RATOS DIABÉTICOS INDUZIDOS POR ALOXANO. / EFFECTS OF RESISTANCE TRAINING ON CHANGES IN VASCULAR REACTIVITY OF DIABETIC RATS INDUCED BY ALLOXAN.
Diabetes mellitus (DM) is presented as a metabolic disorder characterized by chronic hyperglycemia that is associated with endothelial dysfunction (ED). Among the various therapies employed in the improvement of ED, primary prevention, which includes changes in diet and physical training (PT), has been the right one. This study evaluated the effects of resis
Publicado em: 2010
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11. Participação dos canaisTRP nos efeitos cardiovasculares induzidos por carvacrol em ratos / Participation of TRP channel in the cardiovascular effects induced by carvacrol in rat
Os efeitos farmacológicos de carvacrol, um fenol monoterpenóide, sobre o sistema cardiovascular, foi estudado em ratos normotensos, usando técnicas in vivo e in vitro. Carvacrol (10-8 - 3 ₓ 10-4 M) induziu vasorelaxamento dos anéis de artéria mesentérica superior isolada de rato pré-contraídos com 10 μM FEN (pD2 = 4,59 0,02, Emáx
Publicado em: 2010
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12. Investigação do efeito vasorelaxante e caracterização eletrofisiológica dos alcalóides curina e reticulina
It was been demonstrated that curine and reticuline, induced a vasodilator effect in the rat small mesenteric arteries through inhibition of voltage-gated Ca2+ channels (VGCC). These compounds, curine and reticuline were isolated from the root barks of Chondrondendron platyphyllum and Ocotea duckei Vattimo, respectively, therefore the aim of this work was to
Publicado em: 2009