Merozoites
Mostrando 1-12 de 140 artigos, teses e dissertações.
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1. A simple, ex vivo phagocytosis assay of Plasmodium vivax merozoites by flow cytometry
As phagocytosis is the first line of defense against malaria, we developed a phagocytosis assay with Plasmodium vivax (P. vivax) merozoites that can be applied to evaluate vaccine candidates. Briefly, after leukocyte removal with loosely packed cellulose powder in a syringe, P. vivax trophozoites matured to the merozoite-rich schizont stages in the presence
Mem. Inst. Oswaldo Cruz. Publicado em: 07/10/2019
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2. Antibody response against recombinant proteins based on Plasmodium vivax merozoite antigens in individuals from a rural community of the Brazilian Amazonia / Resposta de anticorpos contra proteínas recombinantes baseadas em antígenos de merozoítos de Plasmodium vivax em indivíduos de uma comunidade rural da Amazônia brasileira
In recent years we studied various aspects of the naturally acquired immune response in individuals from different endemic areas of the Amazon region exposed to malaria. For this purpose we used recombinant proteins based on P. vivax blood stage antigens considered candidates for a vaccine against vivax malaria. In the present study, we focused on 396 indivi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/05/2011
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3. TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium
Recently, we described the improved immunogenicity of new malaria vaccine candidates based on the expression of fusion proteins containing immunodominant epitopes of merozoites and Salmonella enterica serovar Typhimurium flagellin (FliC) protein as an innate immune agonist. Here, we tested whether a similar strategy, based on an immunodominant B-cell epitope
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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4. Effect of Solanum nudum steroids on uninfected and Plasmodium falciparum-infected erythrocytes
Steroids from Solanum nudum (SNs) have demonstrated antiplasmodial activity against erythrocytic stages of the Plasmodium falciparum strain FCB-2. It is well known that steroids can alter the membrane function of erythrocytes. Thus, we assessed alterations in the membranes of uninfected red blood cells, the parasite invasiveness and the solute-induced lysis
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-08
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5. Differential expression analysis between merozoites and sporozoites of Eimeria tenella using LongSage. / Análise da expressão diferencial entre merozoítos e esporozoítos de Eimeria tenella empregando a técnica de LongSAGE.
Eimeria tenella is one of the most important causing agents of poultry coccidiosis. To study the quantitative gene expression profile in zoite stages of LongSage libraries were generated from merozoites and sporozoites. More than 35.000 tags were obtained, whose 9.516 were unique. For identification and annotation of differential expressed genes, tags were e
Publicado em: 2009
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6. Theileria electrophorin.sp., a parasite of the electric eel Electrophorus electricus (Osteichthyes: Cypriniformes: Gymnotidae) from Amazonian Brazil
The name Theileria electrophori n.sp. is proposed for a small parasite described in the erythrocytes of the electric eel, Electrophorus electricus, from Amazonian Brazil. Division of the organism in the erythrocyte produces only four bacilliform daughter cells which become scattered in the host cell, without a cruciform or rosette-shaped disposition. Exoeryt
Memórias do Instituto Oswaldo Cruz. Publicado em: 23/02/2007
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7. Some coccidial parasites of the lizard Amphisbaena alba (Reptilia: Amphisbaenia: Amphisbaenidae)
Five parasites are described in the lizard Amphisbaena alba (Amphisbaenidae) from the state of Pará, North Brazil. Mature oocysts of Choleoeimeria amphisbaenae n. sp., are passed already mature in the faeces. They are ellipsoidal-cylindrical, average 33.7 x 22.8 µm and are devoid of micropyle, oocyst residuum or polar body. The colourless wall is smooth an
Memórias do Instituto Oswaldo Cruz. Publicado em: 2003-10
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8. Comparison of the human immune responses to recombinant proteins representing three distinct surface proteins of Plasmodium vivax merozoites
Anais da Academia Brasileira de Ciências. Publicado em: 2000-03
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9. The fine structure of the endogenous stages of Isospora hemidactyli carini, 1936 in the gecko Hemidactylus mabouia from North Brazil
The ultrastructure is described of the meronts, microgamonts and young oocyst stages of Isospora hemidactyli of the gecko Hemidactylus mabouia from Belém, PA, north Brazil. The endogenous stages all develop in the nucleus of the gut epithelial cells. The nucleus remains intact up to the latest stages of the parasite's development, but degenerates by the tim
Memórias do Instituto Oswaldo Cruz. Publicado em: 2000-01
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10. Opsonization and Phagocytosis of Plasmodium falciparum Merozoites Measured by Flow Cytometry
A flow cytometric phagocytosis assay was established to investigate the role of anti-merozoite antibody, complement, and cytokines on the phagocytosis of Plasmodium falciparum merozoites by human neutrophils. This assay involved allowing fluorescein isothiocyanate-labeled merozoites to interact with phagocytes and analysis of the cells on a FACScan with Lysi
American Society for Microbiology.
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11. Effects of cytokines, complement, and antibody on the neutrophil respiratory burst and phagocytic response to Plasmodium falciparum merozoites.
The interaction between Plasmodium falciparum merozoites and human neutrophils, as well as the role of cytokines, complement, and antimalarial antibody on this interaction, was examined in vitro by measuring luminol-dependent chemiluminescence and phagocytosis. Merozoites, in the presence of heat-inactivated (56 degrees C/30 min) normal serum, had very littl
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12. Interactions between Toxoplasma gondii and its host cells: function of the penetration-enhancing factor of toxoplasma.
A protein with a molecular weight of 70,000 to 150,000 which was extracted from merozoites of Toxoplasma gondii enhanced the host cell penetration of the merozoites. The optimal pH and temperature for penetration of merozoites coincided with those favoring the action of the penetration-enhancing protein. In addition, a dependence on Ca and Mg existed for pen