Mdd
Mostrando 1-12 de 91 artigos, teses e dissertações.
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1. O transtorno depressivo pode ser geneticamente herdado?
Sobre os fatores genéticos da depressão, a herdabilidade da depressão ainda não é consenso na literatura cientifica. No entanto, segundo alguns estudos estima-se que 37% dos casos possam ter uma relação genética, mesmo que essas relações sejam posteriormente moduladas pelo ambiente – ou seja, embora os genes possam ser relevantes para o surgim
Núcleo de Telessaúde Mato Grosso do Sul. Publicado em: 12/06/2023
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2. Adolescent depression and resting-state fMRI brain networks: a scoping review of longitudinal studies
The neurobiological factors associated with the emergence of major depressive disorder (MDD) in adolescence are still unclear. Previous cross-sectional studies have documented aberrant connectivity in resting-state functional magnetic resonance imaging (rs-fMRI) networks. However, whether these findings precede MDD onset has not been established. This scopin
Brazilian Journal of Psychiatry. Publicado em: 2022
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3. Does mismatch negativity have utility for NMDA receptor drug development in depression?
Rapid antidepressant effects associated with ketamine have shifted the landscape for the development of therapeutics to treat major depressive disorder (MDD) from a monoaminergic to glutamatergic model. Treatment with ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, may be effective, but has many non-glutamatergic targets, and clinical and logis
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Factors associated with adherence to sports and exercise among outpatients with major depressive disorder
Abstract Introduction Individuals with major depressive disorder (MDD) face more barriers to engagement in sports and exercise interventions. Evaluating clinical and demographic factors associated with adherence to sports and exercise among MDD outpatients could support development of new options and strategies to increase their participation. Methods In
Trends Psychiatry Psychother.. Publicado em: 2021-06
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5. Diagnosis and Management of Depression in CRS: A Knowledge, Attitudes and Practices Survey
Abstract Introduction Comorbid major depressive disorder (MDD) is present in up to 25 % of chronic rhinosinusitis (CRS) cases and provides prognostic information for patients undergoing endoscopic sinus surgery (ESS). Clinical visits offer an opportunity to identify at-risk patients. Objective The purpose of the present study is to evaluate practice patter
Int. Arch. Otorhinolaryngol.. Publicado em: 2021-01
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6. Prevalence and correlates of major depressive disorder: a systematic review
Objectives: Major depressive disorder (MDD) is one of the most disabling mental illnesses and it has a significant impact on society. This review aims to provide updated scientific evidence about the epidemiology of MDD. Methods: A systematic literature review of the PubMed and MEDLINE databases was performed to identify articles on the prevalence of MDD a
Braz. J. Psychiatry. Publicado em: 2020-12
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7. Clinical characteristics of cognitive deficits in major depressive disorder: a 6-month prospective study
Abstract Background Previous studies have shown that major depressive disorder (MDD) is associated with a variety of cognitive deficits, which can persist even in remitted states. Nevertheless, the relationship between the cognitive and affective symptoms in depression remains obscure. The aim of the present study was to explore the clinical characteristic
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2020-08
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8. Precision non-implantable neuromodulation therapies: a perspective for the depressed brain
Current first-line treatments for major depressive disorder (MDD) include pharmacotherapy and cognitive-behavioral therapy. However, one-third of depressed patients do not achieve remission after multiple medication trials, and psychotherapy can be costly and time-consuming. Although non-implantable neuromodulation (NIN) techniques such as transcranial magne
Braz. J. Psychiatry. Publicado em: 2020-08
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9. Adjunctive vortioxetine for SSRI-resistant major depressive disorder: a “real-world” chart review study
Objective: Selective serotonin reuptake inhibitors (SSRIs) are the cornerstone of treatment of major depressive disorder (MDD). However, non-response is common, often necessitating combination strategies. The present study assessed the efficacy of vortioxetine as an add-on therapy in patients with SSRI-resistant MDD. Methods: The charts of 36 adult outpati
Braz. J. Psychiatry. Publicado em: 2020-06
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10. Personality disorder and functioning in major depressive disorder: a nested study within a randomized controlled trial
Objective: This study aimed to determine if personality disorder (PD) predicted functional outcomes in patients with major depressive disorder (MDD). Methods: Data (n=71) from a double-blind, randomized, placebo-controlled 12-week trial assessing the efficacy of 200 mg/day adjunctive minocycline for MDD were examined. PD was measured using the Standardized
Braz. J. Psychiatry. Publicado em: 2020-02
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11. Neuroimaging adolescents with depression in a middle-income country: feasibility of an fMRI protocol and preliminary results
Objective: To test the feasibility and to present preliminary results of a neuroimaging protocol to evaluate adolescent depression in a middle-income setting. Methods: We assessed psychotropic medication-free adolescents (age range 14-16 years) with a diagnosis of major depressive disorder (MDD). Participants underwent a comprehensive clinical evaluation a
Braz. J. Psychiatry. Publicado em: 2020-02
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12. Mental disorders and suicide risk in emerging adulthood: the 1993 Pelotas birth cohort
ABSTRACT OBJECTIVE To assess the prevalence of some mental disorders and suicide risk, and the association between them in youths. METHODS Data from the 1993 Pelotas Birth Cohort (Brazil) was used. The prevalence of mental disorders at 22 years [major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), attention-
Rev. Saúde Pública. Publicado em: 21/10/2019