Matrix Tablet
Mostrando 1-12 de 30 artigos, teses e dissertações.
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1. Validation of a scale to evaluate the abusive use of technologies (Computer, cell phone, tablet, among others)
BACKGROUND INFORMATION: Daily, prolonged interactivity of individuals with technologies (computer, cell phone, tablet, among others) impacts life and significantly changes habits, behaviors, personal and social relationships. Technologies lead to a multitude of advantages, but attention is required concerning possible damages. OBJECTIVE: Validation of a sc
MedicalExpress (São Paulo, online). Publicado em: 04/07/2019
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2. Preparation and in vitro & in vivo evaluation of cephalexin matrix tablets
The purpose of the study is to develop cephalexin controlled-release matrix tablets by using lower proportions of release retardant polymer and to establish their in vitro & in vivo correlation. Tablets were compressed by incorporating polymers in a matrix form along with drug which prolong the drug release. Twelve formulations were prepared by mixing ethyl
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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3. A suppository-base-matrix tablet for time-dependent colon-specific delivery system
Nossa pesquisa focou-se nas principais características de planejamento e de desempenho de liberação cólon-específica tempo-dependente (TDCS) de comprimidos, que leva em conta a constância relativa observada no tempo de trânsito intestinal das formas de dosagem. A doença inflamatória do intestino (IBD) pode afetar o tempo de trânsito e, geralmente,
Braz. J. Pharm. Sci.. Publicado em: 2014-09
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4. Dimensional stability of a novel polyvinyl siloxane impression technique
AIM: To introduce a modification of the reline impression technique (MRIT), and compare the dimensional changes of impressions obtained by MRIT and by conventional reline impression technique (CRIT). METHODS: An acrylic resin tablet was milled by a CAD-CAM system to simulate three abutments (A, B and C) with different distances among them. The abutment
Braz. J. Oral Sci.. Publicado em: 2014-04
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5. Development and evaluation of sustained release losartan potassium matrix tablet using kollidon SR as release retardant
O presente estudo foi realizado para desenvolver (SR) matriz de comprimidos de liberação sustentada de losartana, um antagonista da angiotensina II, para o tratamento da hipertensão arterial. Os comprimidos foram preparados pelo método de compressão direta com Kollidon SR como polímero de liberação lenta. A quantidade de losartana potássica permanec
Braz. J. Pharm. Sci.. Publicado em: 2012-12
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6. Formulation of a modified release metformin. HCl matrix tablet: influence of some hydrophilic polymers on release rate and in-vitro evaluation
O cloridrato de metformina é um agente antidiabético que melhora a tolerância à glicose em pacientes com diabetes tipo 2 e reduz os níveis plasmáticos basais de glicose. Neste estudo, um projeto experimental do tipo "centróide simplex" com 69 tomadas foi usado para selecionar a melhor combinação de alguns polímeros hidrofílicos que gerou um perfil
Brazilian Journal of Pharmaceutical Sciences. Publicado em: 2011-09
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7. Hydroxypropylcellulose controlled release tablet matrix prepared by wet granulation: effect of powder properties and polymer composition
O objetivo deste estudo é desenvolver a liberação 100% da droga cafeína em 24 horas em comprimidos matrizes e investigar o uso de hidroxipropilcelulose (HPC) mais os efeitos de co-excipiente. As propriedades físicas dos pós foram avaliadas assim como seu uso no processo de granulação úmida. O comprimido contendo a cafeína foi formulado por diferent
Brazilian Archives of Biology and Technology. Publicado em: 2009-02
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8. Correlação in vitro in vivo para formas farmacêuticas sólidas de liberação modificada contendo diclofenaco de sódio / In vitro-in vivo correlation for sodium diclofenac modified release tablet formulations
The term in vitro-in vivo correlation (IVIVC) refers to the establishment of a rational relationship between the biological properties, or a parameter derived from a biological property produced by a dosage form, and a physicochemical characteristic or property of the same dosage form. The establishment of IVIVC enables the substitution of in vivo studies fo
Publicado em: 2009
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9. Optimization of controlled release primaquine diphosphate tablets / Otimização da liberação de difosfato de primaquina em comprimidos de liberação controlada
The objective of the present work was to produce primaquine diphosphate controlled release tablets based on hydrophilic polymers and use the mixture statistical experimental design (DOE) to optimize drug release. In selecting the components of the formulations, differential scanning calorimetry (DSC) were carried out to verify the compatibility between drug/
Publicado em: 2009
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10. Simultaneous spectrophotometric determination of ezetimibe and simvastatin in pharmaceutical preparations using chemometric techniques
Two spectrophotometric methods are described for the simultaneous determination of ezetimibe (EZE) and simvastatin (SIM) in pharmaceutical preparations. The obtained data was evaluated by using two different chemometric techniques, Principal Component Regression (PCR) and Partial Least-Squares (PLS-1). In these techniques, the concentration data matrix was p
Química Nova. Publicado em: 2008
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11. XANTHAN AND GALACTOMANANN FROM SEEDS OF M. scabrella AS HYDROPHYLIC MATRICES OF THEOPHYLLINE / GOMA XANTANA E GALACTOMANANA (M. scabrella): DESENVOLVIMENTO DE MATRIZES HIDROFÍLICAS PARA LIBERAÇÃO MODIFICADA DE TEOFILINA
Directly compressed theophylline tablets were produced containing commercial Xanthan (X) (Keltrol) and a highly hydrophyllic galactomannan (G) from the seeds of Mimosa scabrella, (a Brazilian leguminous tree, called bracatinga) as a release-controlling agent, isolated or in mixture (X:G 1:1), at 8, 12.5 and 25% of gums. In the galactomannan extraction proces
Publicado em: 2005
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12. Compressed matrix core tablet as a quick/slow dual-component delivery system containing ibuprofen
The purpose of the present research was to produce a quick/slow biphasic delivery system for ibuprofen. A dual-component tablet made of a sustained release tableted core and an immediate release tableted coat was prepared by direct compression. Both the core and the coat contained a model drug (ibuprofen). The sustained release effect was achieved with a pol
Springer-Verlag.