Maternal Fetal Tolerance
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. The role of HSP 60 in leucocytes cells of bovine placenta / O papel da HSP 60 nas células leucocitárias da placenta bovina
The maternal-fetal tolerance involves, besides the immune system, many peculiarities regarding the type of placenta and placentation. The bovine placenta is considered not invasive and, as consequence of a superficial implantation without endometrial invasion, it establishes itself as complex barrier that interposes between the maternal and fetal circulation
Publicado em: 2009
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2. Apoptose em placenta de mulheres com e sem hipótese de infecção por Streptococcus agalactiae/
Recent advances in Obstetrics and Neonatology improved the attendance to the pregnant and newborn, identifying factors that raise maternal and fetal morbi-mortality. Amongst the main risk factors for neonatal sepsis are the premature parturition and the premature rupture of membranes, which increases the chances of maternal colonization by the Group B Strept
Publicado em: 2009
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3. Imunofenotipagem de leucócitos da placenta bovina / Immunophenotyping of leukocytes in the bovine placenta
Linfócitos e macrófagos são os principais tipos de leucócitos envolvidos no processo de tolerância materno-fetal. Os linfócitos são divididos em sub-populações de acordo com sua função e fenótipo, apesar de serem morfologicamente semelhantes. Seus tipos incluem os linfócitos T, linfócitos B e natural killers (NK). Macrófagos são células que
Publicado em: 2009
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4. Degradation of tryptophan in bovine placenta in normal and cloned pregnancy: is this an evidence of indoleamine 2,3-dioxygenase activity? / Degradação de triptofano na placenta bovina em gestações normais e de clones: evidência da atividade da indoleamina 2,3-dioxigenase?
A tolerância materno-fetaI continua a ser um intrigante enigma imunológico. Algumas teorias têm sido propostas sobre o estabelecimento deste estado, tais como a produção de moléculas solúveis como HLA-G (na gestação humana) por células fetais que inibiriam a atividade de células do sistema imune inato. Além da secreção de hormônios; liberaçã
Publicado em: 2005
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5. Diagnostico imunologico e efeito de imunizações com linfocitos em pacientes com aborto espontaneo recorrente
t: Pregnancy can be considered as a very successful all graft, but the underlying mechanism is not yet completely understood. HLA all tigens compatibility is very important in c1inic transplant due to their all ore cognition by immune system. Nevertheless, genetic differences between maternal and paternal HLA antigens seem to be an important factor for impla
Publicado em: 1998
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6. Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface
The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune system at the feto-maternal interface, cit
BioMed Central.
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7. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis
HLA-G is a nonclassical major histocompatibility complex class I molecule selectively expressed on cytotrophoblasts at the feto–maternal interface, where it may play an important role in maternal tolerance of the fetus. We provide direct evidence under physiological conditions that supports the role of HLA-G in protecting cytotrophoblasts against natural k
The National Academy of Sciences of the USA.
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8. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum.
Rare nucleated fetal cells circulate within maternal blood. Noninvasive prenatal diagnosis by isolation and genetic analysis of these cells is currently being undertaken. We sought to determine if genetic evidence existed for persistent circulation of fetal cells from prior pregnancies. Venous blood samples were obtained from 32 pregnant women and 8 nonpregn
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9. Maternal obesity accelerates fetal pancreatic β-cell but not α-cell development in sheep: prenatal consequences
Maternal obesity affects offspring weight, body composition, and organ function, increasing diabetes and metabolic syndrome risk. We determined effects of maternal obesity and a high-energy diet on fetal pancreatic development. Sixty days prior to breeding, ewes were assigned to control [100% of National Research Council (NRC) recommendations] or obesogenic
American Physiological Society.
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10. Placental expression of the nonclassical MHC class I molecule Mamu-AG at implantation in the rhesus monkey
During human implantation trophoblasts mediate attachment of the embryo to the uterine epithelium and invade and reorganize vessels of the maternal endometrium to initiate blood flow to the intervillous space. Expression of the nonclassical MHC class I molecule HLA-G by invading trophoblasts may play a central role in their protection from recognition by the
The National Academy of Sciences.
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11. In utero exposure to helminth and mycobacterial antigens generates cytokine responses similar to that observed in adults.
Neonates exposed to parasite antigens (Ags) in utero may develop altered fetal immunity that could affect subsequent responses to infection. We hypothesized that cord blood lymphocytes (CBL) from offspring of mothers residing in an area highly endemic for schistosomiasis, filariasis, and tuberculosis in Kenya would either fail to respond or generate a predom
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12. Phenylketonuria: variable phenotypic outcomes of the R261Q mutation and maternal PKU in the offspring of a healthy homozygote.
Phenylketonuria (PKU) and benign hyperphenylalaninaemia (HPA) result from a variety of mutations in the gene for the hepatic enzyme phenylalanine hydroxylase. PKU has been found in the Israeli population in two variants, classical and atypical. The two are clinically indistinguishable and require treatment with low phenylalanine diet to prevent mental retard