Mammary Neoplasia
Mostrando 13-24 de 36 artigos, teses e dissertações.
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13. Regulating factors of angiogênese and tumoral infiltration in positive the mammary carcinomas for citoqueratina 5 / Fatores reguladores da angiogênese e infiltração tumoral nos carcinomas mamários positivos para a citoqueratina 5
O reconhecimento de subtipos de carcinomas mamários baseados em suas características moleculares trouxe novas perspectivas na investigação do câncer de mama. Algumas proteínas chaves reguladoras da angiogênese e da infiltração tumoral foram avaliadas em carcinomas de mama de fenótipo basal (CK5+). Foi realizado estudo Imunoistoquímico com 14 antic
Publicado em: 2006
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14. Morphological changes induced by testosterone in the mammary glands of female Wistar rats
Increased levels of androgens in postmenopausal women are considered to be a risk factor for breast cancer. Testosterone, alone or in combination with estrogen, induces epithelial dysplasia and mammary tumors in Noble rats. Since this model of hormone-induced neoplasia has not been reported in other rat strains, we studied the effect of testosterone on the m
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-04
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15. Scintigraphic evaluation of mammary glands lymphatic drainage and vascularization in female dogs / Avaliação cintilográfica da vascularização e drenagem linfática das glândulas mamárias de cadelas
A identificação e biópsia do primeiro linfonodo a receber a linfa de uma formação neoplásica, ou seja, do linfonodo sentinela, fornecem informações essenciais para o tratamento e prognóstico de pacientes humanos acometidos por neoplasia. Entretanto, em Medicina Veterinária existem poucos estudos sobre a drenagem linfática dos órgãos e o conceito
Publicado em: 2005
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16. Psicossociais aspects of the auto-examination: implications in one another look of the prevention of the breast cancer / Aspectos psicossociais do auto-exame: implicações num outro olhar da prevenção do câncer de mama
The breast cancer is a pathology that has crescent incidence, in the countries of higher degree of development like in the countries in development. There are evidences that its causes seem to have relation to modern life style, of difficult control. In this context, the efforts are direct to secondary prevention, in order to make an early diagnosis of tumor
Publicado em: 2004
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17. In vivo positron-emission tomography imaging of progression and transformation in a mouse model of mammary neoplasia
Imaging mouse models of human cancer promises more effective analysis of tumor progression and reduction of the number of animals needed for statistical power in preclinical therapeutic intervention trials. This study utilizes positron emission tomography imaging of 2-[18F]-fluoro-deoxy-d-glucose to monitor longitudinal development of mammary intraepithelial
National Academy of Sciences.
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18. ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.
ApcMin (Min, multiple intestinal neoplasia) is a point mutation in the murine homolog of the APC gene. Min/+ mice develop multiple intestinal adenomas, as do humans carrying germ-line mutations in APC. Female mice carrying Min are also prone to develop mammary tumors. Min/+ mammary glands are more sensitive to chemical carcinogenesis than are +/+ mammary gla
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19. Mammary cancer and epithelial stem cells: a problem or a solution?
The existing paradigms for stem cells in adult tissues include the integument, the alimentary canal, the lung, the liver, skeletal muscle and bone marrow. The mammary gland, by contrast, is the 'new kid on the block'. What little is known about stem cells in the mammary gland indicates that they possess a prodigious capacity for self-renewal. More importantl
BioMed Central.
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20. Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands
In this report we document the creation of transgenic mice in which the native ratio of A and B forms of progesterone receptor (PR) has been altered by the introduction of additional A form as transgene. We also show that in these mice there is an aberration in mammary development. In ovariectomized prepubertal PR-A transgenic mice, end buds with unusual mor
The National Academy of Sciences.
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21. Progesterone receptors - animal models and cell signaling in breast cancer: Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics
The progesterone receptor knockout mouse demonstrated progesterone's importance to parity-induced mammary tertiary branching and lobuloalveologenesis. Because early parity provides significant protection against breast cancer whereas prolonged exposure to premenopausal ovarian progesterone (or to postmenopausal supplementations thereof) has been linked to br
BioMed Central.
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22. Homeobox genes in mammary gland development and neoplasia
Both normal development and neoplastic progression involve cellular transitions from one physiological state to another. Whereas much is being discovered about signal transduction networks involved in regulating these transitions, little progress has been made in identifying the higher order genetic determinants that establish and maintain mammary cell ident
BioMed Central.
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23. Methylation and amplification of mouse mammary tumor virus DNA in normal, premalignant, and malignant cells of GR/A mice.
The methylation and amplification of mouse mammary tumor virus (MuMTV) proviral DNA was investigated in normal, premalignant, and malignant tissues of GR/A mice. The proviral methylation pattern was examined with the restriction enzyme HhaI, which fails to cleave methylated DNA. MuMTV proviral DNA from liver, kidney, and heart was highly methylated. Proviral
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24. Three dimensional anatomy of complete duct systems in human breast: pathological and developmental implications.
AIMS: To reconstruct the arrangement in space of all major ducts and their branches from nipple to periphery of a human breast obtained at necropsy. METHODS: Duct tracing through cleared haematoxylin stained 2 mm sub-gross coronal slices of a complete necropsy breast and computer modelling of duct territories. RESULTS: All branches were traced for 10 complet