Mammary Metabolism
Mostrando 1-12 de 32 artigos, teses e dissertações.
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1. Changes in maternal body composition and metabolism of dairy goats during pregnancy
The objective of this study was to evaluate the mobilization of nutrients in goats of different gestation types and pregnancy stages. Forty-four Saanen and Oberhasli goats were studied. The goats of each breed and gestation type (single or twin) were slaughtered at different gestational ages (80, 110, and 140 days of pregnancy), forming a completely randomiz
R. Bras. Zootec.. Publicado em: 2015-03
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2. Lack of chemopreventive activity of vitamin A when administered to rats during the stage of post-initiation of mammary carcinogenesis / Ausência de atividade quimiopreventiva por parte da vitamina A quando administrada a ratas na etapa de pós-iniciação da carcinogênese mamária
Avaliou-se a eventual atividade quimiopreventiva por parte da vitamina A (VA) quando administrada a ratas Sprague-Dawley durante a etapa de pós-iniciação da carcinogênese mamária induzida pelo 7-12 dimetilbenz(a)antraceno (DMBA). Com exceção de 10 animais que constituíram um grupo controle à parte de ratas consideradas normais [grupo normal (N)], e
Publicado em: 2010
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3. Efeito da vitamina D no perfil transcricional de cultura organotípica de câncer de mama / Vitamin D effect in the transcriptional profile of breast cancer organotypic culture
High 1,25(OH)2D3 (VD) concentrations (10-100nM) exerts antiproliferative effects and modifies gene expression profile in breast cancer (BC) cell lines. However, studies conducted in cell lines disconsider stromal-epithelium interactions, which are known to regulate breast cancer development. Besides, high VD concentrations may cause hypercalcemia in vivo. Ou
Publicado em: 2010
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4. Polymorphism in CYP17, GSTM1 and the progesterone receptor genes and its relationship with mammographic density
Radiologic breast density is one of the predictive factors for breast cancer and the extent of the density is directly related to postmenopause. However, some patients have dense breasts even during postmenopause. This condition may be explained by the genes that codify for the proteins involved in the biosynthesis, as well as the activity and metabolism of
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-04
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5. Arterial concentration and mammary gland uptake of metabolites and ClA concentration in goats milk in response to dietary sources of polyunsaturated fatty acids or increasing amounts of soybean oil / Concentração arterial, retenção de metabólitos pela glândula mamária e concentração de CLA no leite de cabras, em resposta à ingestão de fontes de ácidos graxos poliinsaturados ou doses crescentes de óleo de soja
Os objetivos dos experimentos (I e II) foram avaliar os efeitos da inclusão de 2% de fontes de ácidos graxos poliinsaturados (óleo de soja, de linhaça e de peixe) e doses crescentes de óleo de soja (0, 30, 60 e 90 g/dia) sobre o consumo, digestibilidade dos nutrientes no trato digestório total, produção e composição do leite, perfil de ácidos grax
Publicado em: 2008
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6. Expressão gênica diferencial de fibroblastos de linfonodos comprometidos ou não comprometidos de pacientes com câncer de mama após cultura isolada ou co-cultura com células epiteliais mamárias normais ou malignas / Differential gene expression of fibroblasts from involved or uninvolved lymph nodes from breast cancer patients cultured alone or cocultured with normal or malignant mammary epithelial cells
Tumor development may be influenced by epithelial-mesenchimal interactions in the primary site as well as in the involved lymph node from breast cancer patients. Our aim was to evaluate the proliferation rate and gene profile of fibroblasts obtained from involved and uninvolved lymph nodes from breast câncer patients and to determine the influence of normal
Publicado em: 2007
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7. Protein and energy metabolism and study of mammary parenchyma morphology in dairy goats with different αs1- casein genotypes / Metabolismo protéico e energético e estudo ultra-estrutural da glândula mamária de cabras lactantes de diferentes genótipos para alpha s1-caseína
Considerando a hipótese de que variações no gene da αs1-caseína possam afetar o metabolismo protéico e energético em cabras lactantes, e em conseqüência suas exigências nutricionais, uma série de três experimentos foi elaborada para analisar esta possibilidade, avaliando-se o desempenho animal, a eficiência de uso da proteína e da energia,
Publicado em: 2007
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8. Effects of conjugated linoleic acid (cla) supplementation on milk composition, fatty acids profile and lipogenic enzymes activity in lactating rats. / Efeito da suplementação com ácido linoléico conjugado (CLA) na composição do leite, no perfil de ácidos graxos e na atividade de enzimas lipogênicas em ratas lactantes.
CLA has a range of biological properties, including effects on lipid metabolism, milk and body composition in animals. This study investigated the effects of dietary CLA on lactating rats and development of the suckling rats. Dams were fed either with a control diet or a diet supplemented with 2.5% of calcium salts of CLA containing 60% of CLA (CLA-60, Churc
Publicado em: 2003
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9. Evaluation of phagocytes from healthy buffaloes (Bubalus bubalis) milk bred in Sao Paulo state / Avaliação dos fagócitos no leite de búfalas (Bubalus bubalis) hígidas criadas no Estado de São Paulo
The aim of this study was to make a quantitative and a qualitative evaluation of phagocytes from healthy buffaloes (Bubalus bubalis) milk bred in Sao Paulo state. For this purpose, the experiment was divided in three parts, called chapters, as specific objectives: (1) establish and study the cellularity of healthy buffaloes milk; (2) establish an adequate me
Publicado em: 2002
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10. Isolation of an inhibitor of DNA synthesis specific for normal and malignant mammary cells.
A small-molecular-weight inhibitor of DNA synthesis, specific for normal and malignant mammary cells but devoid of species-specificity, has been isolated from bovine mammary glands. This factor has very little effect on RNA metabolism.
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11. The gene for the neuropeptide gonadotropin-releasing hormone is expressed in the mammary gland of lactating rats.
The high concentration of gonadotropin-releasing hormone (GnRH) in milk of several species implies that the mammary gland is either a site of synthesis for this neuropeptide or that it is efficiently concentrated from plasma by this organ. By PCR amplification of mammary gland cDNA, we have demonstrated expression of the mRNA for GnRH. The GnRH mRNA was pres
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12. Sex steroid influence on triglyceride metabolism.
Triglyceride metabolism was investigated in groups of fed and fasted rats after 21 days of parenteral estradiol (5 mug daily), progesterone (5 mg daily), or the two steroids in combination. Results were compared with control groups receiving an oil solvent alone. In rats given estradiol separately or combined with progesterone, hypertriglyceridemia was unifo