Major Depressive Disorder
Mostrando 1-12 de 142 artigos, teses e dissertações.
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1. O transtorno depressivo pode ser geneticamente herdado?
Sobre os fatores genéticos da depressão, a herdabilidade da depressão ainda não é consenso na literatura cientifica. No entanto, segundo alguns estudos estima-se que 37% dos casos possam ter uma relação genética, mesmo que essas relações sejam posteriormente moduladas pelo ambiente – ou seja, embora os genes possam ser relevantes para o surgim
Núcleo de Telessaúde Mato Grosso do Sul. Publicado em: 12/06/2023
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2. Immature defense mechanisms predict poor response to psychotherapy in major depressive patients with comorbid cluster B personality disorder
Objective: To evaluate the impact of defense mechanisms at baseline on depressive symptoms after brief psychotherapies and after 6-months of follow-up among depressed patients with and without cluster B personality disorders (PDs). Methods: This quasi-experimental study nested within a randomized clinical trial included a clinical sample of adults (18-60 ye
Brazilian Journal of Psychiatry. Publicado em: 2022
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3. Evening chronotype as a bipolar feature among patients with major depressive disorder: the results of a pilot factor analysis
Objectives: The bipolar spectrum concept has resulted in a paradigm shift that has affected both the diagnosis and therapy of mood disorders, with bipolarity becoming an indicator of treatment resistance in depression. Evening circadian preference has also been linked to affective disorders. The aim of our study was to confirm the relationship between the se
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Low-dose ketamine does not improve the speed of recovery from depression in electroconvulsive therapy: a randomized controlled trial
Objective: Electroconvulsive therapy (ECT) is a well-established therapeutic intervention for major depressive disorder. Recent literature has shown that the anesthetic agent ketamine has some antidepressant properties at low doses and may be an alternative therapy for treatment-resistant major depressive disorder. We hypothesized that the use of low-dose ke
Brazilian Journal of Psychiatry. Publicado em: 2022
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5. Adolescent depression and resting-state fMRI brain networks: a scoping review of longitudinal studies
The neurobiological factors associated with the emergence of major depressive disorder (MDD) in adolescence are still unclear. Previous cross-sectional studies have documented aberrant connectivity in resting-state functional magnetic resonance imaging (rs-fMRI) networks. However, whether these findings precede MDD onset has not been established. This scopin
Brazilian Journal of Psychiatry. Publicado em: 2022
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6. Does mismatch negativity have utility for NMDA receptor drug development in depression?
Rapid antidepressant effects associated with ketamine have shifted the landscape for the development of therapeutics to treat major depressive disorder (MDD) from a monoaminergic to glutamatergic model. Treatment with ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, may be effective, but has many non-glutamatergic targets, and clinical and logis
Brazilian Journal of Psychiatry. Publicado em: 2022
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7. Association between exposure to toxoplasmosis and major psychiatric disorders: a systematic review
Objective: To assess the association between exposure to toxoplasmosis and major psychiatric disorders through a systematic review of the literature. Methods: The literature review was performed in the MEDLINE, SciELO, and PsycINFO databases. To evaluate the quality of the studies included in the review, the Newcastle-Ottawa Scale was used. Results: Thirt
Braz. J. Psychiatry. Publicado em: 2021-08
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8. Cardiovascular risk factors and major depressive disorder: a cross-sectional study in São Paulo, Brazil
ABSTRACT BACKGROUND: Cardiovascular risk factors can mediate the association between depression and cardiovascular diseases. OBJECTIVE: To evaluate cardiovascular risk factors in adult individuals with and without histories of major depression in the metropolitan region of São Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study in São Paulo (SP), B
Sao Paulo Med. J.. Publicado em: 2021-08
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9. Factors associated with adherence to sports and exercise among outpatients with major depressive disorder
Abstract Introduction Individuals with major depressive disorder (MDD) face more barriers to engagement in sports and exercise interventions. Evaluating clinical and demographic factors associated with adherence to sports and exercise among MDD outpatients could support development of new options and strategies to increase their participation. Methods In
Trends Psychiatry Psychother.. Publicado em: 2021-06
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10. The role of the microbiota-gut-brain axis in neuropsychiatric disorders
The microbiota-gut-brain axis is a bidirectional signaling mechanism between the gastrointestinal tract and the central nervous system. The complexity of the intestinal ecosystem is extraordinary; it comprises more than 100 trillion microbial cells that inhabit the small and large intestine, and this interaction between microbiota and intestinal epithelium c
Braz. J. Psychiatry. Publicado em: 2021-06
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11. A Brazilian adaptation of the Affective and Cognitive Measure of Empathy
The microbiota-gut-brain axis is a bidirectional signaling mechanism between the gastrointestinal tract and the central nervous system. The complexity of the intestinal ecosystem is extraordinary; it comprises more than 100 trillion microbial cells that inhabit the small and large intestine, and this interaction between microbiota and intestinal epithelium c
Braz. J. Psychiatry. Publicado em: 2021-06
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12. Vortioxetine improved olfactory reference syndrome in a patient with major depressive disorder: A case report
Resumo Este artigo tem como objetivo discutir a existência de uma afinidade entre a estética de relatos cotidianos, testemunhos e diários com a experiência específica da pandemia do Covid-19. Partimos da ideia de que uma característica bastante compartilhada na experiência da pandemia tem sido o foco nos traços desse momento histórico na vida cotidi
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2021-04