M Leprae
Mostrando 1-12 de 428 artigos, teses e dissertações.
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1. Como acontece a transmissão da hanseníase?
A transmissão da hanseníase ainda não é totalmente conhecida. A principal via de transmissão é a respiratória, por inalação de gotículas contendo o agente causador, Mycobacterium leprae (M. leprae). Uma pessoa doente que apresenta a forma infectante da doença (multibacilar – MB), estando sem tratamento, elimina o bacilo pelas vias respiratór
Núcleo de Telessaúde Santa Catarina. Publicado em: 12/06/2023
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2. Social school contacts of multibacillary leprosy cases in children living in the hyperendemic region of the Midwest of Brazil
Abstract Objective: To analyze the prevalence of Mycobacterium leprae detection and the associated factors among social contacts in the school environment of multibacillary cases living in a hyperendemic municipality of the state of Mato Grosso. Methods: Cross-sectional study with 236 social contacts of multibacillary leprosy from public schools and reside
Jornal de Pediatria. Publicado em: 2022
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3. Armadillos and leprosy: from infection to biological model
ABSTRACT Mycobacterium leprae is the primary causative agent of Hansen’s disease or leprosy. Besides human beings, natural infection has been described in animals such as mangabey monkeys and armadillos. Leprosy is considered a global health problem and its complete pathogenesis is still unknown. As M. leprae does not grow in artificial media, armadillos h
Rev. Inst. Med. trop. S. Paulo. Publicado em: 12/09/2019
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4. Expression of FoxP3 in different forms of leprosy and reactions
RESUMO Embora as células T reguladoras (Treg) sejam importantes na regulação imunológica de vários processos patológicos, o papel delas na imunologia da hanseníase ainda precisa ser mais bem avaliado. O objetivo deste trabalho é quantificar o nuclear transcription factor P3 (FoxP3), principal marcador de células Treg, nas diferentes formas de hansen
J. Bras. Patol. Med. Lab.. Publicado em: 02/09/2019
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5. Reading of the Mitsuda test: comparison between diameter and total area by means of a computerized method
ABSTRACT The Mitsuda test is a skin test based on the individual’s immune response through late and highly specific hypersensitivity reaction to the Mycobacterium leprae bacillus. A negative reaction identifies individuals who present a higher risk of becoming ill if exposed to M. leprae and, if they become ill, to develop the virchowian form of disease. T
Rev. Inst. Med. trop. S. Paulo. Publicado em: 14/02/2019
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6. Compreendendo a “alta em hanseníase”: uma análise de conceito
Resumo OBJETIVO Analisar o conceito de alta em hanseníase. MÉTODOS Estudo teórico pautado no referencial metodológico de análise de conceito. Realizou-se levantamento bibliográfico, de dezembro de 2015 a janeiro de 2016, nas bases SCOPUS, CINAHL, PUBMED, LILACS, SCIELO e BDENF, mediante uso dos descritores “Hanseníase” e “Alta do Paciente”,
Rev. Gaúcha Enferm.. Publicado em: 07/06/2018
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7. Utility of immunoglobulin isotypes against LID-1 and NDO-LID for, particularly IgG1, confirming the diagnosis of multibacillary leprosy
BACKGROUND Leprosy remains a health problem in many countries, with difficulties in diagnosis resulting in delayed treatment and more severe disabilities. Antibodies against several Mycobacterium leprae antigens have, however, shown value as diagnostic and/or prognostic markers. OBJECTIVES The objective of this study was to evaluate serum immunoglobulin
Mem. Inst. Oswaldo Cruz. Publicado em: 26/02/2018
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8. Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae
BACKGROUND The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. OBJECTIVE The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local population in five municipalities in the state of Ceará,
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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9. ELISA-based assay of immunoglobulin G antibodies against mammalian cell entry 1A (Mce1A) protein: a novel diagnostic approach for leprosy
BACKGROUND Leprosy is a chronic infectious disease caused by the obligate intracellular bacillus Mycobacterium leprae. Because leprosy diagnosis is complex and requires professional expertise, new tools and methodologies are needed to detect cases in early stages and prevent transmission. The M. leprae genome contains mce1A, which encodes a putative mammali
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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10. Salivary anti-PGL-1 IgM may indicate active transmission of Mycobacterium leprae among young people under 16 years of age
Abstract Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection. The study aimed to analyze salivary anti-PGL-1 IgA and IgM antibodies in 169 children aged 4-16 years old, who lived nearby or inside the house of multibacillary or
Braz J Infect Dis. Publicado em: 2017-10
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11. Presence of Mycobacterium leprae genotype 4 in environmental waters in Northeast Brazil
Abstract INTRODUCTION: This study quantified Mycobacterium leprae bacilli in environmental water samples from five municipalities in the State of Ceará by quantitative polymerase chain reaction (qPCR) and compared the identified genotypes with those obtained from leprosy patient biopsies. METHODS: We collected five replicas from each of the 30 selected re
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-03
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12. qPCR detection of Mycobacterium leprae in biopsies and slit skin smear of different leprosy clinical forms
Abstract Leprosy, whose etiological agent is Mycobacterium leprae, is a chronic infectious disease that mainly affects the skin and peripheral nervous system. The diagnosis of leprosy is based on clinical evaluation, whereas histopathological analysis and bacilloscopy are complementary diagnostic tools. Quantitative PCR (qPCR), a current useful tool for diag
Braz J Infect Dis. Publicado em: 2017-02