Lysosensor
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Investigation of phagotrophy in natural assemblages of the benthic dinoflagellates Ostreopsis, Prorocentrum and Coolia
Resumo A mixotrofia tem se mostrado uma característica comum entre dinoflagelados e a sua importância na ecologia nutricional de algas nocivas vem sendo investigada. Espécies bentônicas nocivas não foram tão estudadas quanto as planctônicas, e existem grandes lacunas no conhecimento de suas estratégias nutricionais. A ocorrência de fagotrofia em com
Braz. j. oceanogr.. Publicado em: 2017-09
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2. Internalização e tráfego da Stress Inducible Protein-1 (STI-1), um ligante da proteína prion celular
The cellular prion protein (PrPc) is a glycosylphosphatidylinositol (GPI)-anchored plasma membrane glycoprotein. The PrPc abnormal isoform, PrPsc, is an infectious form involved in the prion disease pathogenesis. Identification of ligands that interact with PrPc can help in the understanding the physiological function of this protein. The STI-1 (stress induc
Publicado em: 2006
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3. Insulin-like Growth Factor-I Prevents the Accumulation of Autophagic Vesicles and Cell Death in Purkinje Neurons by Increasing the Rate of Autophagosome-to-lysosome Fusion and Degradation*
Continuous macroautophagic activity is critical for the maintenance of neuronal homeostasis; however, unchecked or dysregulated autophagy can lead to cell death. Cultured Purkinje neurons die by an autophagy-associated cell death mechanism when deprived of trophic support. Here, we report that insulin-like growth factor-I (IGF-I) completely blocked the autop
American Society for Biochemistry and Molecular Biology.
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4. Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm
Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is pathogenic for humans, primarily those with compromised immune function. CN is believed to be a facultative intracellular pathogen. Time-lapsed video microscopy revealed that yeast began to replicate and divide 2 hours after ingestion by J774.16 macrophage cells, with the avera
The National Academy of Sciences.
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5. Intracellular Trafficking of Brucella abortus in J774 Macrophages
Brucella abortus is a facultative intracellular bacterium capable of surviving inside professional and nonprofessional phagocytes. The microorganism remains in membrane-bound compartments that in several cell types resemble modified endoplasmic reticulum structures. To monitor the intracellular transport of B. abortus in macrophages, the kinetics of fusion o
American Society for Microbiology.