Lymphocyte Proliferation
Mostrando 13-24 de 784 artigos, teses e dissertações.
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13. Production optimization and characterization of immunomodulatory peptides obtained from fermented goat placenta
The goat placental immunomodulatory peptides were produced by fermentation with Aspergillus Niger. The objective of the present study was to investigate the effects of fermentation parameters (carbon source content, pH, and time) on spleen lymphocyte proliferation for the highest immune activity of the fermentation broth using response surface methodology (R
Food Sci. Technol. Publicado em: 2014-12
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14. Leukocytosis, muscle damage and increased lymphocyte proliferative response after an adventure sprint race
The effect of an adventure sprint race (ASR) on T-cell proliferation, leukocyte count and muscle damage was evaluated. Seven young male runners completed an ASR in the region of Serra do Espinhaço, Brazil. The race induced a strong leukocytosis (6.22±2.04×103 cells/mm3 before vs 14.81±3.53×103 cells/mm3 after the race), marked by a significant increase
Braz J Med Biol Res. Publicado em: 2014-06
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15. Modulation of cell proliferation, survival and gene expression by RAGE and TLR signaling in cells of the innate and adaptive immune response: role of p38 MAPK and NF-KB
Objective: The aim of this study was to evaluate a possible synergism between AGE-RAGE and TLR4 signaling and the role of p38 MAPK and NF-kB signaling pathways on the modulation of the expression of inflammatory cytokines and proliferation of cells from the innate and adaptive immune response. Material and Methods: T lymphocyte (JM) and monocyte (U937) ce
J. Appl. Oral Sci.. Publicado em: 2014-06
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16. Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation
Dendritic cells (DCs) are antigen (Ag)-presenting cells that activate and stimulate effective immune responses by T cells, but can also act as negative regulators of these responses and thus play important roles in immune regulation. Pro-angiogenic vascular endothelial growth factor (VEGF) has been shown to cause defective DC differentiation and maturation.
Mem. Inst. Oswaldo Cruz. Publicado em: 09/10/2013
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17. Enhanced immune response of a bicistronic DNA vaccine expressing fusion antigen Hsp65-Esat-6 of Mycobacterium Tuberculosis with GM-CSF as a molecular adjuvant
This study aimed to construct a bicistronic DNA vaccine expressing fusion antigen Hsp65-Esat-6 of Mycobacterium tuberculosis with cytokine GM-CSF as a molecular adjuvant (pIRES-Hsp65-ESAT-6-GM-CSF, pIRHEG), and the immune response in mice. C57BL/6 mice were immunized with the recombinant plasmid to detect the titer of antibodies, lymphocyte proliferation, th
Braz. arch. biol. technol.. Publicado em: 2013-10
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18. Efeito da saliva de Aedes aegypti sobre a diferenciação, maturação e função de células dendríticas e na proliferação de linfócitos T. / Effect of Aedes aegypti saliva on the differentiation, maturation and function of dendritic cells and on T lymphocyte proliferation.
Mosquitos são os mais importantes vetores de patógenos humanos, transmitindo um amplo espectro de doenças infecciosas emergentes e reemergentes. Nesse cenário, o mosquito Aedes aegypti está entre as espécies mais relevantes. No presente estudo investigamos as atividades do extrato de glândula salivar (EGS) desse mosquito vetor na biologia das células
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2012
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19. A novel noninvasive method to detect rejection after heart transplantation
Prompt and accurate detection of rejection prior to pathological changes after organ transplantation is vital for monitoring rejections. Although biopsy remains the current gold standard for rejection diagnosis, it is an invasive method and cannot be repeated daily. Thus, noninvasive monitoring methods are needed. In this study, by introducing an IL-2 neutra
Braz J Med Biol Res. Publicado em: 2012-12
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20. Distinct cytokine profiles of circulating mononuclear cells stimulated with Staphylococcus aureus enterotoxin A in vitro during early and late episodes of chronic osteomyelitis
We investigated the cytokine profile of peripheral mononuclear cells from chronic osteomyelitis (OST) patients following in vitro stimulation with staphylococcal enterotoxin A (SEA). We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-α, interleukin (IL)-4 and IL-10 secretion in
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-05
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21. Recognition of enteroinvasive Escherichia coli and Shigella flexneri by dendritic cells: distinct dendritic cell activation states
The innate and adaptive immune responses of dendritic cells (DCs) to enteroinvasive Escherichia coli (EIEC) infection were compared with DC responses to Shigella flexneri infection. EIEC triggered DCs to produce interleukin (IL)-10, IL-12 and tumour necrosis factor (TNF)-α, whereas S. flexneri induced only the production of TNF-α. Unlike S. flexneri, EIEC
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-02
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22. Resposta imune de suínos imunizados pela via nasal com proteínas de roptrias do Toxoplasma gondii
Toxoplasma gondii is an obligate intracellular parasite that infects a wide range of hosts including human beings. Herbivores are the main domestic infection sources for humans, and pork is considered the most important route of transmission. Recent decades have witnessed a great increasing in the number of technologies and immunological research to produce
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/03/2011
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23. Desenvolvimento e avaliação imunológica de Nanotubos de Carbono funcionalizados com a proteína de envelope de Dengue virus 3
In terms of epidemiologic impact, Dengue (DENV) infections represent the most important infectious disease in Brazil. Consequently, the development of an efficient vaccine is considered a high priority. Due to this fact, many studies are being developed towards this goal, but no vaccine is currently available to the population. Carbon Nanotubes (CNT) have be
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2011
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24. Immune response to dna vaccine expressing transferrin binding protein a gene of Pasteurella multocida
Haemorrhagic Septicaemia (HS), an acute and fatal disease of cattle and buffalo is primarily caused by serotype B:2 or E:2 of Pasteurella multocida. The transferrin binding protein A (TbpA) has been found to act as immunogen and potent vaccine candidate in various Gram negative bacteria including P. multocida. The present study was carried out to evaluate th
Brazilian Journal of Microbiology. Publicado em: 2011-06