Lung Mechanics
Mostrando 1-12 de 113 artigos, teses e dissertações.
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1. Hypercapnia attenuates ventilator-induced lung injury through vagus nerve activation
Abstract Purpose: To investigate the role of vagus nerve activation in the protective effects of hypercapnia in ventilator-induced lung injury (VILI) rats. Methods: Male Sprague-Dawley rats were randomized to either high-tidal volume or low-tidal volume ventilation (control) and monitored for 4h. The high-tidal volume group was further divided into either
Acta Cir. Bras.. Publicado em: 25/11/2019
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2. Influencia de la caja torácica en el monitoreo de la mecánica respiratoria en síndrome de distrés respiratorio agudo
ABSTRACT The respiratory system mechanics depend on the characteristics of the lung and chest wall and their interaction. In patients with acute respiratory distress syndrome under mechanical ventilation, the monitoring of airway plateau pressure is fundamental given its prognostic value and its capacity to assess pulmonary stress. However, its validity can
Rev. bras. ter. intensiva. Publicado em: 2018-06
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3. Chronic heart failure modifies respiratory mechanics in rats: a randomized controlled trial
ABSTRACT Objective To analyze respiratory mechanics and hemodynamic alterations in an experimental model of chronic heart failure (CHF) following myocardial infarction. Method Twenty-seven male adult Wistar rats were randomized to CHF group (n=12) or Sham group (n=15). Ten weeks after coronary ligation or sham surgery, the animals were anesthetized and sub
Braz. J. Phys. Ther.. Publicado em: 08/04/2016
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4. Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory effects of administering a single intravenous dose of 7.5% hypertonic saline in an experimental model of
Clinics. Publicado em: 2015-08
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5. Oscillation mechanics of the respiratory system in never-smoking patients with silicosis: pathophysiological study and evaluation of diagnostic accuracy
OBJECTIVES: Silicosis is a chronic and incurable occupational disease that can progress even after the cessation of exposure. Recent studies suggest that the forced oscillation technique may help to clarify the changes in lung mechanics resulting from silicosis as well as the detection of these changes. We investigated the effects of airway obstruction in s
Clinics. Publicado em: 2013-05
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6. Tratamento com inibidor da Rho quinase em cobais com inflamação pulmonar alérgica crônica: modulação da inflamação eosinofílica, da expressão de citocinas inflamatórias, da matriz extracelular e do estresse oxidativo no parênquima pulmonar / Treatment with Rho-kinase inhibitor in guinea pigs with chronic allergic inflammation: modulation of eosinophilic inflammation, expression of inflammatory cytokines, extracellular matrix and oxidative stress in lung tissue
RATIONALE: Previous studies with Rho-kinase inhibitors suggest a beneficial influence of these drugs in asthma. The relevance of distal lung tissue in functional asthmatic impairment has been intensely emphasized. There have not been any previous studies evaluating the effects of these inhibitors on the modulation of distal lung mechanics and histopathologic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/12/2012
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7. Estudo do funcionamento da ventilação assistida proporcional plus em um sistema pulmonar mecânico / Study of the functioning of the proportional assist ventilation plus in a mechanical lung model
INTRODUÇÃO: Ventilação assistida proporcional plus é um novo conceito de suporte ventilatório assistido que visa atuar de acordo com os níveis de esforço inspiratório, mecânica respiratória e níveis de porcentagem de apoio. A complexa interação entre esses fatores que comandam a sua função é de difícil interpretação na prática clínica.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/08/2012
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8. Efeitos fisiológicos da ventilação de alta frequência usando ventilador convencional em um modelo experimental de insuficiência respiratória grave / Physiological effects of high frequency ventilation with conventional ventilator in an experimental model of severe respiratory failure
Introduction: Acute respiratory distress syndrome (ARDS) has a high incidence and mortality between critical ill patients. The mechanical ventilation is the most important support for these patients with ARDS. However, until now there is an important debate about how is the best ventilatory strategy to use, because the mechanical ventilation if not well set
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2012
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9. Imagem e mecânica pulmonar regional em duas estratégias protetoras de ventilação mecânica (ARDSNet versus PEEP ajustada pela tomografia de impedância elétrica): um estudo de longo prazo em modelo experimental / Image and regional lung mechanics in two protective ventilatory strategies (ARDSNet versus PEEP adjusted by electrical impedance tomography): a long term experimental model study
Introdução: As estratégias ventilatórias protetoras têm contribuído para a redução da letalidade da Síndrome do Desconforto Respiratório Agudo (SDRA), mas ainda está em debate qual, entre as diversas existentes, é a mais eficaz. A estratégia ARDSNet, muito utilizada na prática clínica, prioriza a redução do volume corrente para minimizar a h
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/04/2012
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10. EFEITO DO 1,8 CINEOL NOS PARÂMETROS DE CONTRATILIDADE DO MÚSCULO LISO TRAQUEAL E DE MECÂNICA DO SISTEMA RESPIRATÓRIO DE RATOS EXPOSTOS A FUMAÇA DO CIGARRO / EFFECT OF THE PARAMETERS 1.8 cineole muscle contractility TRACHEAL SMOOTH AND MECHANICS OF RESPIRATORY SYSTEM OF RATS EXPOSED TO CIGARETTE SMOKE OF
O 1,8-cineol é um oxido monoterpenico, antinflamatório e miorelaxante nas vias aéreas e já mostrou atividade em diversos tipos de tecidos excitáveis incluindo diversos tipos de músculo liso. Sabe-se hoje que a fumaça do cigarro é um poluente capaz de provocar doenças principalmente no trato respiratório podendo alterar o mecanismo contrátil do mú
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/03/2012
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11. Comparison of Celsior and Perfadex lung preservation solutions in rat lungs subjected to 6 and 12 hours of ischemia using an ex-vivo lung perfusion system
OBJECTIVE: This study evaluated the performance of lungs that were preserved with different solutions (Celsior, Perfadex or saline) in an ex vivo rat lung perfusion system. METHODS: Sixty Wistar rats were anesthetized, anticoagulated and randomized into three groups (n = 20). The rats were subjected to antegrade perfusion via the pulmonary artery with Perfad
Clinics. Publicado em: 2012-11
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12. The effect of acute magnesium loading on the maximal exercise performance of stable chronic obstructive pulmonary disease patients
OBJECTIVE: The potential influence of magnesium on exercise performance is a subject of increasing interest. Magnesium has been shown to have bronchodilatatory properties in asthma and chronic obstructive pulmonary disease patients. The aim of this study was to investigate the effects of acute magnesium IV loading on the aerobic exercise performance of stabl
Clinics. Publicado em: 2012