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Mostrando 1-12 de 10155 artigos, teses e dissertações.
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1. A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans
Abstract XRN2 is an evolutionarily conserved 5’-to-3’ exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for embryogenesis, larval development and reproduction in Caenorhabditis elegans, relevant molecular pathways remain unidentified. Here we create a germline-specific xrn-2 conditional mutant and p
Genetics and Molecular Biology. Publicado em: 2023
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2. Editorial Comment: Testosterone replacement therapy (TRT) and prostate cancer: An updated systematic review with a focus on previous or active localized prostate cancer
International braz j urol. Publicado em: 2022
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3. Management of Iatrogenic Aortic Dissections During Percutaneous Right Coronary Artery Interventions
ABSTRACT Iatrogenic acute aortic dissections during percutaneous coronary interventions are an extremely rare but potentially life-threatening complication, occurring in less than 0.02% of transcatheter procedures. We report three patients with different characteristics suffering from iatrogenic aortic dissection during percutaneous coronary intervention suc
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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4. Pelvic lymph node dissection in high-risk prostate cancer
ABSTRACT Introduction: The therapeutic role of pelvic lymph node dissection (PLND) in prostate cancer (PCa) is unknown due to absence of randomized trials. Objective: to present a critical review on the therapeutic benefits of PLND in high risk localized PCa patients. Materials and Methods: A search of the literature on PLND was performed using PubMed, Co
International braz j urol. Publicado em: 2022
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5. A novel nomogram can predict pathological T3a upstaged from clinical T1a in localized renal cell carcinoma
ABSTRACT Hypothesis: Nomogram can be built to predict the pathological T3a upstaging from clinical T1a in patients with localized renal cell carcinoma before surgery. Purpose: Renal cell carcinoma (RCC) patients with clinical T1a (cT1a) disease who are upstaged to pathological T3a (pT3a) have reduced survivals after partial nephrectomy. We aimed to develop
International braz j urol. Publicado em: 2022
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6. An introduction to male breast cancer for urologists: epidemiology, diagnosis, principles of treatment, and special situations
ABSTRACT Breast cancer (BC) is mainly considered a disease in women, but male BC (MaBC) accounts for approximately 1.0% of BC diagnoses and 0.5% of malignant neoplasms in the western population. The stigmatization of MaBC, the fact that men are less likely to undergo regular health screenings, and the limited knowledge of health professionals about MaBC cont
International braz j urol. Publicado em: 2022
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7. COMPREENDENDO OS MECANISMOS DE CORROSÃO DE LIGAS DE AL-CU-LI: UMA INVESTIGAÇÃO ATRAVÉS DE TÉCNICAS ELETROQUÍMICAS GLOBAIS E LOCAIS
In this study, the corrosion mechanism of an Al-Cu-Li alloy manufactured by two different treatment routes (T3 and T851) was evaluated by immersion and electrochemical tests in solutions containing chloride ions (Cl-). For both alloys, the formation of cavities on the surface was associated with micrometer-sized intermetallics (IM’s), however, in addition
Química Nova. Publicado em: 2022
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8. Stress fractures
ABSTRACT Stress fractures (SF) represent 10%-20% of all injuries in sport medicine. An SF occurs when abnormal and repetitive loading is applied on normal bone: The body cannot adapt quickly enough, leading to microdamage and fracture. The etiology is multifactorial with numerous risk factors involved. Diagnosis of SF can be achieved by identifying intrinsic
Archives of Endocrinology and Metabolism. Publicado em: 2022
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9. Cushing’s syndrome due to ectopic adrenocorticotropin secretion by a parotid carcinoma
SUMMARY We report a rare case of Cushing’s syndrome in a 37-year-old female who initially presented with localized acinic cell carcinoma of the parotid gland. In January 2014, she underwent a right parotidectomy with facial nerve preservation and adjuvant radiotherapy. In August 2018, she presented a histologically-proven local regional relapse. The patien
Archives of Endocrinology and Metabolism. Publicado em: 2022
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10. Presenting signs and symptoms of artificial urinary sphincter cuff erosion
ABSTRACT Purpose To characterize the most common presentation and clinical risk factors for artificial urinary sphincter (AUS) cuff erosion to distinguish the relative frequency of symptoms that should trigger further evaluation in these patients. Materials and Methods We retrospectively reviewed our tertiary center database to identify men who presented
International braz j urol. Publicado em: 2022
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11. Should obesity be associated with worse urinary continence outcomes after robotic-assisted radical prostatectomy? a propensity score matching analysis
ABSTRACT Purpose: To analyze the association between obesity and urinary incontinence rate in men submitted to robot-assisted radical prostatectomy (RARP) in a high-volume cancer center. Materials and Methods: We reported 1.077 men who underwent RARP as the primary treatment for localized prostate cancer from 2013 to 2017. Patients were classified as non-o
International braz j urol. Publicado em: 2022
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12. Available evidence on HIFU for focal treatment of prostate cancer: a systematic review
ABSTRACT Purpose: Prostate cancer (PCa) is the second most common oncologic disease among men. Radical treatment with curative intent provides good oncological results for PCa survivors, although definitive therapy is associated with significant number of serious side-effects. In modern-era of medicine tissue-sparing techniques, such as focal HIFU, have bee
International braz j urol. Publicado em: 2022