Llc Pk1
Mostrando 1-12 de 85 artigos, teses e dissertações.
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1. A New Steroidal Saponin from the Tubers of Ophiopogon japonicus and Its Protective Effect Against Cisplatin-Induced Renal Cell Toxicity
A new furostanol saponin, ophiopogonin T, was isolated from the tubers of Ophiopogon japonicus. Its structure was established by extensive spectroscopic techniques including 1D (1H and 13C) and 2D nuclear magnetic resonance (NMR) experiments (correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond correlati
J. Braz. Chem. Soc.. Publicado em: 2016-04
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2. Nefrotoxicidade da polimixina B: estudo experimental em células e implicações para a prática de enfermagem
O objetivo do estudo foi caracterizar os mecanismos de lesão celular envolvidos na fisiopatologia da citotoxicidade da polimixina B em células tubulares proximais (LLC-PK1) e discutir as proposições de intervenção do enfermeiro para identificar os pacientes de risco e considerar a prevenção ou o tratamento para lesão renal nefrotóxica. Estudo exper
Rev. esc. enferm. USP. Publicado em: 2014-04
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3. Polimixina B: efeito dose e tempo dependente na nefrotoxicidade in vitro
OBJETIVO: Caracterizar a toxicidade da polimixina B (PmxB) em células renais em dosagem e tempos diferentes. MÉTODOS: Células LLC-PK1, cultivadas em placas multiwell de 12 poços, foram divididas nos seguintes grupos: Controle (CTL) - células mantidas em meio DMEM suplementado a 5%; G1 - células expostas à concentração de 75mM de PmxB; G2 - células
Acta paul. enferm.. Publicado em: 2013
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4. Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein
Nephrotoxicity is the main side effect of antibiotics such as gentamicin. Preconditioning has been reported to protect against injuries as ischemia/reperfusion. The objective of the present study was to determine the effect of preconditioning with gentamicin on LLC-PK1 cells. Preconditioning was induced in LLC-PK1 cells by 24-h exposure to 2.0 mM gentamicin
Brazilian Journal of Medical and Biological Research. Publicado em: 22/05/2009
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5. Efeito da uroguanilina sobre o transporte de hidrogênio em túbulos renais de rins de rato e em linhagens de células proximais e distrais / Effect of Uroguanylin on hydrogen transport in rat renal tubules and in proximal and distal cells lines
Uroguanilina (UGN) é um peptídeo normalmente sintetizado no intestino que modula o balanço de sódio através de ações renais. Investigamos os efeitos e os mecanismos de sinalização envolvidos na ação da UGN sobre a secreção de H+, em túbulos renais de ratos e em células LLC-PK1 (proximais) e MDCK-C11 (distais). Nos estudos in vivo foi utilizada
Publicado em: 2009
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6. Toxicidade da polimixina B em células LLC-PK1 e a enzima heme oxigenase-1 / Polymyxin B toxicity in LLC-PK1 cells and the heme oxygenase-1 enzyme
In the acute kidney injury, the mechanisms of defense act as protector genes, as the protein heat shock 32 (HSP 32), also known as heme oxygenase-1 (HO-1). The polymyxin B (PmxB) is a nephrotoxic antimicrobial. The aim of this study was to distinguish the role of the HO-1 enzyme in the PmxB toxicity in LLC-PK1 cells. The cells were submitted to the following
Publicado em: 2008
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7. Electrical parameters and water permeability properties of monolayers formed by T84 cells cultured on permeable supports
T84 is an established cell line expressing an enterocyte phenotype whose permeability properties have been widely explored. Osmotic permeability (P OSM), hydraulic permeability (P HYDR) and transport-associated net water fluxes (J W-transp), as well as short-circuit current (I SC), transepithelial resistance (R T), and potential difference (deltaV T) were me
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
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8. Desempenho e Predição de Híbridos e Análise de Agrupamento de Características de Matrizes de Frangos de Corte
Este trabalho foi conduzido com cruzamentos (dialelo parcial) entre as linhas do grupo I (LL, TL, ZL, TT, LT, ZT, ZZ, LZ e TZ) e as linhas do grupo II (PP, KP, VP, KK, PK, VK, VV, PV e KV), além de duas linhas (LLc e PPc) controle. O delineamento experimental foi em blocos casualizados consistindo de três blocos, 82 cruzamentos e nove fêmeas por cruzament
Revista Brasileira de Zootecnia. Publicado em: 2002
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9. Insulin and serum increase the number of receptors for vasopressin in a kidney-derived line of cells grown in a defined medium.
A continuous strain of epithelial cells (LLC-PK1L) derived initially from pig kidney grows in a defined medium without serum or hormones. The epithelia from domes, a manifestation of transepithelial transport. The parent cell line, LLC-PK1, forms similar eithelia and has vasopressin-sensitive adenylate cyclase. In this study the binding of 3H-labeled [Lys8]v
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10. Changes in Sodium Pump Expression Dictate the Effects of Ouabain on Cell Growth*
Here we show that ouabain-induced cell growth regulation is intrinsically coupled to changes in the cellular amount of Na/K-ATPase via the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway. Ouabain increases the endocytosis and degradation of Na/K-ATPase in LLC-PK1, human breast (BT20), and prostate (DU145) cancer cells. H
American Society for Biochemistry and Molecular Biology.
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11. Sodium butyrate increases glucose transporter expression in LLC-PK1 cells.
The effect of sodium butyrate on the expression of the facilitated glucose transporter (GT) was investigated in the pig kidney cell line LLC-PK1. When cells were treated with butyrate, GT mRNA expression was remarkably enhanced with a maximal effect at 5 mM. Levels of GT mRNA were increased at 1 day after butyrate treatment and continued to increase for at l
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12. Activation of Caspases in Pig Kidney Cells Infected with Wild-Type and CrmA/SPI-2 Mutants of Cowpox and Rabbitpox Viruses
The cowpox virus (CPV) CrmA and the equivalent rabbitpox virus (RPV) SPI-2 proteins have anti-inflammatory and antiapoptosis activity by virtue of their ability to inhibit caspases, including the interleukin-1β-converting enzyme (ICE; caspase-1). Infection of LLC-PK1 pig kidney cells with a CPV CrmA mutant, but not with wild-type (wt) CPV, results in the in
American Society for Microbiology.