Lipoxygenase
Mostrando 1-12 de 445 artigos, teses e dissertações.
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1. Zn treatment effects on biological potential of fennel bulbs as affected by in vitro digestion process
Abstract Zn treatment effects on the stability of polyphenols, MDA (malondialdehyde) content, antioxidant and lipoxygenase inhibition activities of two varieties of fennel bulbs were studied by using an in vitro gastrointestinal digestion model. Likewise, the effect of Zn on viability cells of E. coli was also performed. The results revealed that high amount
Food Sci. Technol. Publicado em: 2020-06
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2. Isolation, in vitro and in silico Evaluation of Phenylethanoid Glycoside from Arrabidaea brachypoda as Lipoxygenase Inhibitor
Lipoxygenase (LOX) plays an important role in inflammatory processes and Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) has been described as presenting anti-inflammatory activity. Therefore, the objective of this study was to develop a high-performance liquid chromatography (HPLC) procedure to directly recognize LOX inhibitor compounds in A. brachypoda c
J. Braz. Chem. Soc.. Publicado em: 2020-04
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3. Chemical composition and lipoxygenase activity of soybean (Glycine max L. Merrill.) genotypes, specific for human consumption, with different tegument colours
Resumo Recentemente, no Brasil, cultivares de tegumento colorido estão sendo desenvolvidas, como as de tegumentos marrom e preto. A soja com tegumento preto tem sido amplamente utilizada há décadas, devido aos seus benefícios para a saúde e ao uso na medicina popular oriental em razão da presença de fitoquímicos. Estes foram reconhecidos como ingredi
Braz. J. Food Technol.. Publicado em: 25/04/2019
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4. Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones
It was synthesized nine polyoxygenated chalcones with a potential and safe use as antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones obtained by Claisen-Schmidt condensation were studied as antioxidant, inhibitors of human 5-lipoxygenase, antifungal, antibacterial and antibiotic resistance modifiers. Two chalcones with catecholic moieties
J. Braz. Chem. Soc.. Publicado em: 2019-02
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5. Eicosanoids and cancer
Eicosanoids are 20-carbon bioactive lipids derived from the metabolism of polyunsaturated fatty acids, which can modulate various biological processes including cell proliferation, adhesion and migration, angiogenesis, vascular permeability and inflammatory responses. In recent years, studies have shown the importance of eicosanoids in the control of physiol
Clinics. Publicado em: 09/08/2018
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6. Lipoxygenase inhibitors flavonoids from Cyperus rotundus aerial parts
ABSTRACT Cyperus rotundus L. (Suada, Sueda, family: Cyperaceae) is vastly spread in several world's subtropical and tropical regions. It had variable traditional uses and bioactivities. A new flavonol derivative: cyperaflavoside (myricetin 3,3',5'-trimethyl ether 7-O-β-D-glucopyranoside) and five flavonoids: vitexin, orientin, cinaroside, quercetin 3-O-β-D
Rev. bras. farmacogn.. Publicado em: 2018-06
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7. Anti-inflammatory and antioxidant activities of the Impatiens noli-tangere and Stachys officinalis polyphenolic-rich extracts
ABSTRACT This study evaluated the anti-inflammatory and antioxidant activities of Impatiens noli-tangere L., Balsaminaceae, and of Stachys officinalis L., Lamiaceae, polyphenolic-rich extracts obtained by nanofiltration process. Results showed the great potential and efficiency of the nanofiltration process to concentrate the herbal extract's main polyphenol
Rev. bras. farmacogn.. Publicado em: 2018-01
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8. Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect
Abstract Background Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives. These are multi-mediated pathologies that cannot be effectively protected and/or treated. Therefore, the aim of this study was to establish a new model of acut
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/04/2017
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9. Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides
ABSTRACT A series of molecules bearing multiple functional groups were synthesized to study their antibiotic effect against Gram-positive and Gram-negative bacteria and lipoxygenase activity as well. 2,4-Dimethylcarbolic acid (1) was refluxed with ethyl 2-bromoacetate to synthesize ethyl 2-(2,4-dimethylphenoxy)acetate (2). Compound 2 was converted to the cor
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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10. UEL 175: a novel lipoxygenase-free soybean cultivar with kunitz trypsin inhibitor absence
UEL 175 is lipoxygenase-free soybean cultivar and has absence of the antinutritional factors kunitz trypsin inhibitor (SKTI). UEL 175 presents high yield potential and good adaptation under no-tillage. It is resistant to soybean stem canker, brown stem rot, frogeye leaf spot, and bacterial pustule.
Crop Breed. Appl. Biotechnol.. Publicado em: 2015-09
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11. Ciclooxigenase-2 modula in vivo a expressão de marcadores da osteoclastogênese e genes envolvidos no metabolismo ósseo em resposta ao lipopolissacarídeo bacteriano / Ciclooxygenase-2 modulates in vivo the expression of osteoclastiogenesis makers and genes involved in bone metabolism in response to bacterial lipopolysaccharide
During an inflammatory response, several mediators are locally released in order to stimulate cellular and humoral immune response. Through the action of cyclooxygenase and lipoxygenase enzymes structural changes occur in the arachidonic acid chain leading to synthesis of prostaglandins or leukotrienes and lipoxins, respectively. Such mediators are responsib
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/06/2012
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12. Papel de SOCS2 na resposta imune e função cardíaca durante a infecção experimental por Trypanosoma cruzi
Infection with Trypanosoma cruzi induces robust inflammation that limits parasite proliferation but may result in Chagas heart disease. The 5-Lipoxygenase pathway induces suppressor of cytokine signaling(SOCS)2 expression, an important regulator of immune responses. Here, we investigated the role of SOCS2 for the pathogenesis of T. cruzi infection. We invest
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/12/2011