Lipid Mediators
Mostrando 1-12 de 103 artigos, teses e dissertações.
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1. Microbiological, lipid and immunological profiles in children with gingivitis and type 1 diabetes mellitus
Abstract Objective The aim of this study was to compare the prevalence of periodontal pathogens, systemic inflammatory mediators and lipid profiles in type 1 diabetes children (DM) with those observed in children without diabetes (NDM), both with gingivitis. Material and methods Twenty-four DM children and twenty-seven NDM controls were evaluated. The pe
J. Appl. Oral Sci.. Publicado em: 2017-04
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2. Ferulic acid lowers body weight and visceral fat accumulation via modulation of enzymatic, hormonal and inflammatory changes in a mouse model of high-fat diet-induced obesity
Previous studies have reported on the glucose and lipid-lowering effects of ferulic acid (FA) but its anti-obesity potential has not yet been firmly established. This study investigated the possible anti-obesitogenic effects of FA in mice fed a high-fat diet (HFD) for 15 weeks. To assess the antiobesity potential of FA, 32 male Swiss mice, weighing 20–25 g
Braz J Med Biol Res. Publicado em: 05/01/2017
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3. Nutraceutical preconditioning with arginine and oil mixes. Effects on inflammatory mediators, oxidative stress and lipid profile in patients undergoing radical prostatectomy
PURPOSE: To investigate whether there is any effect resulting from preconditioning with nutraceutical supplementation containing arginine and oil mixes with high ω9:ω6 ratio and low ω6:ω3 ratio containing EPA and DHA, ALA fatty acids on inflammatory mediators, antioxidant and lipid profile modulation in surgical trauma.METHODS:Twenty-six men scheduled fo
Acta Cir. Bras.. Publicado em: 2014-08
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4. Effects of propofol in lipid-based emulsion and in microemulsion on the incidence of endothelial lesion in rabbits
PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME). METHODS: Forty-two rabbits (2.5-4.5 Kg) were randomly allocated into seven groups of six animals each: SHAM- surgical treatment alone; Bolus Control Group - 3 mL-intravenous (IV) bolus
Acta Cir. Bras.. Publicado em: 2013-12
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5. Nitro-fatty acids: novel anti-inflammatory lipid mediators
Nitro-fatty acids are formed and detected in human plasma, cell membranes, and tissue, modulating metabolic as well as inflammatory signaling pathways. Here we discuss the mechanisms of nitro-fatty acid formation as well as their key chemical and biochemical properties. The electrophilic properties of nitro-fatty acids to activate anti-inflammatory signaling
Braz J Med Biol Res. Publicado em: 06/09/2013
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6. Mapping and signaling of neural pathways involved in the regulation of hydromineral homeostasis
Several forebrain and brainstem neurochemical circuitries interact with peripheral neural and humoral signals to collaboratively maintain both the volume and osmolality of extracellular fluids. Although much progress has been made over the past decades in the understanding of complex mechanisms underlying neuroendocrine control of hydromineral homeostasis, s
Braz J Med Biol Res. Publicado em: 12/04/2013
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7. Effects of omega-3 fatty acids on regulatory T cells in hematologic neoplasms
The development of leukemia and lymphomas is related to the increase in inflammatory process modulators. These, in turn, have divergent actions on the neoplastic process. Populations of T cells have different roles in the neoplastic environment; while interferon-gamma positive T cells have antitumor activity, the FoxP3+interleukin-10 positive population pres
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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8. Terapia laser de baixa intensidade a 808 nm reduz a resposta inflamatória e favorece a regeneração muscular
Muscle regeneration is a complex phenomenon, involving coordinated activation of several cellular responses. During this process, oxidative stress, and consequent tissue damage occur with a severity that may depend on the intensity and duration of the inflammatory response. Among the therapeutic approaches to attenuate inflammation and increase tissue repair
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
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9. Hypertonic saline solution reduces the inflammatory response in endotoxemic rats
OBJECTIVE: Volume replacement in septic patients improves hemodynamic stability. This effect can reduce the inflammatory response. The objective of this study was to evaluate the effect of 7.5% hypertonic saline solution versus 0.9% normal saline solution for volume replacement during an inflammatory response in endotoxemic rats. METHODS: We measured cytokin
Clinics. Publicado em: 2012-12
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10. Efeito protetor da N-acetilcisteína na evolução precoce de receptores de transplante renal com doador falecido / Protective effect of N-acetylcysteine on early outcomes of deceased renal transplant
INTRODUCTION Deceased renal transplant graft survival rates are worse than those from living donors. Reactive oxygen metabolites are believed to be important mediators of various forms of acute kidney injury, such as ischaemic renal failure, radiocontrast nephrotoxicity and ureteral obstruction. The aim of this study is to investigate the therapeutic effects
Publicado em: 2010
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11. Role of leukotrienes in immune protection conferred by the heterologous immunization BCG/DNA-HSP65 against tuberculosis / Papel dos leucotrienos na proteção conferida pela imunização heteróloga BCG/DNA-HSP65 contra tuberculose
Tuberculosis is responsible for more than 2 millions of death for year. The immune response against tuberculosis is related to activation of IFN-g-producing CD4+ and CD8+ cells. IFN-g increases the microbicidal mechanisms of macrophages to kill intracellular bacilli. Recently, the lipid mediator leukotriene B4 (LTB4) has been related to protection against se
Publicado em: 2009
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12. Studies about the effects of the in vivo administration of Leukotriene B4 or Prostaglandin E2-loaded biodegradable microspheres on model of murine histoplasmosis / Estudos sobre os efeitos da administração in vivo de microesferas biodegradáveis contendo Leucotrieno B4 ou Prostaglandina E2 em modelo de histoplasmose murina
Leukotrienes and prostaglandins are arachidonic acid metabolites, which participate in the inflammatory response and modulate cytokines release in both adaptive and innate immune responses. However, some physicochemical characteristics of these mediators, such as poor solubility in water and chemical instability, make them difficult to administer in vivo. In
Publicado em: 2008