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Mostrando 1-12 de 136 artigos, teses e dissertações.
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1. Evaluation of toxin-antitoxin genes, antibiotic resistance, and virulence genes in Pseudomonas aeruginosa isolates
SUMMARY OBJECTIVE: Toxin-antitoxin genes RelBE and HigBA are known to be involved in the formation of biofilm, which is an important virulence factor for Pseudomonas aeruginosa. The purpose of this study was to determine the presence of toxin-antitoxin genes and exoenzyme S and exotoxin A virulence genes in P. aeruginosa isolates and whether there is a rela
Revista da Associação Médica Brasileira. Publicado em: 2023
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2. Characteristics and outcomes of COVID-19 patients assisted by intensivists and nonintensivists
SUMMARY OBJECTIVE: The aim of this study was to assess the outcomes of critically ill patients with COVID-19 in an intensive care unit seen by a care team formed by intensive and nonintensive physicians and treatment guided by processes and protocols linked to the “choosing wisely” concept, comparing them with similar data recently published. METHODS:
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. Long non-coding RNA HOTAIR induces the PI3K/AKT/mTOR signaling pathway in breast cancer cells
SUMMARY OBJECTIVE: The phosphoinositide 3-kinase/protein kinase AKT/mammalian target of rapamycin signaling pathway is essential for proper cellular metabolism and cell growth. However, aberrant activation of this pathway has been linked to the progression and metastasis of breast cancer. Recently, the role of long non-coding RNAs in interfering with the ce
Revista da Associação Médica Brasileira. Publicado em: 2022
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4. Evaluation of platelet indices and pro-inflammatory cytokines in type 2 diabetic patients with retinopathy
SUMMARY OBJECTIVE: The aim of this study was to investigate whether platelet parameters and pro-inflammatory cytokines associated with platelet activation could be surrogate markers of the diabetic retinopathy stages in type 2 diabetic patients. METHODS: This prospective case-control study included 108 type 2 diabetes mellitus patients and 48 healthy contr
Revista da Associação Médica Brasileira. Publicado em: 2022
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5. The relation of dermcidin with insulin resistance and inflammation in women with polycystic ovary syndrome
SUMMARY OBJECTIVE: Polycystic ovary syndrome is the most common endocrinopathy among women of reproductive age. Polycystic ovary syndrome is a metabolic disorder associated with insulin resistance and subclinical inflammation. Dermcidin, an antimicrobial peptide, involves in insulin resistance and inflammatory processes. Dermcidin suppresses the secretion o
Revista da Associação Médica Brasileira. Publicado em: 2022
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6. Investigation of serum phoenixin levels in patients with hypertension
SUMMARY OBJECTIVE: Hypertension is a major modifiable risk factor for cardiovascular disease and premature death worldwide. Phoenixin is a newly identified neuropeptide with multiple bioactivity. However, there was no published data about phoenixin levels in hypertension. The aim of this study was to evaluate the relationship between phoenixin and hypertens
Revista da Associação Médica Brasileira. Publicado em: 2022
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7. Evaluation of serum ghrelin, nesfatin-1, irisin, and vasoactive intestinal peptide levels in temporal lobe epilepsy patients with and without drug resistance: a cross-sectional study
SUMMARY OBJECTIVE: Epilepsy is a common disorder that affects the nervous systems of 1% of worldwide population. In epilepsy, one-third of patients are unresponsive to current drug therapies and develop drug-resistant epilepsy. Alterations in ghrelin, nesfatin-1, and irisin levels with epilepsy were reported in previous studies. Vasoactive intestinal peptid
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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8. Fabry disease: genetics, pathology, and treatment
SUMMARY Fabry disease (FD) is a recessive monogenic inheritance disease linked to chromosome X, secondary to mutations in the GLA gene. Its prevalence is estimated between 1:8,454 and 1:117,000 among males and is probably underdiagnosed. Mutations in the GLA gene lead to the progressive accumulation of globotriaosylceramide (Gb3). Gb3 accumulates in lysosome
Rev. Assoc. Med. Bras.. Publicado em: 13/01/2020
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9. HIF-1α Levels in patients receiving chemoradiotherapy for locally advanced non-small cell lung carcinoma
RESUMO OBJETIVO Examinar a relação entre a resposta ao tratamento e os níveis de fator 1 induzida por hipóxia (HIF-1α) em pacientes com câncer de pulmão de células não pequenas localmente avançado (NSCLC) que receberam quimiorradioterapia (CRT). MÉTODO Oitenta pacientes com NSCLC foram incluídos no estudo e foram tratados na Faculdade de Medi
Rev. Assoc. Med. Bras.. Publicado em: 07/11/2019
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10. Evidence of validity of the Competence Scale of Actions of Nurses in Emergencies
RESUMO Objetivo: avaliar evidências de validade da Escala de Competências das Ações do Enfermeiro em Emergências com base na estrutura interna, na consistência interna e no critério externo. Métodos: estudo metodológico para verificação de novas evidências de validade da Escala, com conteúdos previamente validados. A Escala com 81 ações mens
Rev. Latino-Am. Enfermagem. Publicado em: 18/03/2019
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11. Brinquedos Educativos Associados à Contação de Histórias Aplicados a uma Criança com Deficiência Múltipla
RESUMO: Este estudo teve por objetivo analisar os efeitos dos brinquedos educativos associados à contação de histórias na interação de uma criança com deficiência múltipla. Participou do estudo uma criança de dez anos com diagnóstico de deficiência múltipla (paralisia cerebral e deficiência visual). Foi empregado o delineamento de sujeito únic
Rev. bras. educ. espec.. Publicado em: 2019-03
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12. Hematopoietic Stem Cell Transplantation in Mucopolysaccharidosis Type II: A Literature Review and Critical Analysis
Abstract Mucopolysaccharidosis II (MPS II—Hunter syndrome) is an X-linked lysosomal storage disorder caused by a deficiency in iduronate-2 sulfatase. Enzyme replacement therapy does not cross the blood–brain barrier (BBB), limiting the results in neurological forms of the disease. Another treatment option for MPS, hematopoietic stem cell transplantation
J. inborn errors metab. screen.. Publicado em: 28/02/2019