Linear Stability
Mostrando 37-48 de 565 artigos, teses e dissertações.
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37. Determination of Mirabegron in rat plasma by UPLC–MS/MS after oral and intravenous administration
RESUMO Mirabegron é um tipo de agonista do receptor adrenérgico beta 3 que demonstra eficácia no tratamento de bexiga hiperativa. Nesta pesquisa, o método UPLC-MS/MS é desenvolvido e validado para o estudo da farmacocinética mirabegron em ratos. Um método de precipitação de proteínas é aplicado para a preparação de amostras com acetonitrilo. 397
Rev. Assoc. Med. Bras.. Publicado em: 2019-02
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38. Forced degradation of gliquidone and development of validated stability-indicating HPLC and TLC methods
Forced degradation studies of gliquidone were conducted under different stress conditions. Three degradates were observed upon using HPLC and TLC and elucidated by LC-MS and IR. HPLC method was performed on C18 column using methanol-water (85:15 v/v) pH 3.5 as a mobile phase with isocratic mode at 1 mL.min-1 and detection at 225 nm. HPLC analysis was applied
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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39. Evaluation of the Folin-Ciocalteu Method and Quantification of Total Tannins in Stem Barks and Pods from Libidibia ferrea (Mart. ex Tul) L. P. Queiroz
ABSTRACT The stem bark and pods of “jucá” are widely used in Brazilian folk medicine and, despite their therapeutic relevancies, there are insufficient reports about their quality control. Both herbal drugs from the species are rich in tannins, which showed a lot of biological and economic interest. Thus, the purpose of this study was to evaluate the me
Braz. arch. biol. technol.. Publicado em: 14/11/2018
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40. Numerical experiments with the Generalized Finite Element Method based on a flat-top Partition of Unity
Abstract The Stable Generalized Finite Element Method (SGFEM) is essentially an improved version of the Generalized Finite Element Method (GFEM). Besides of retaining the good flexibility for constructing local enriched approximations, the SGFEM has the advantage of presenting much better conditioning than that of the conventional GFEM. Actually, bad conditi
Lat. Am. j. solids struct.. Publicado em: 29/10/2018
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41. Fast Spectrophotometric Determination of Iodine Value in Biodiesel and Vegetable Oils
Iodine value is an important quality parameter for evaluation of the oxidative stability of biodiesel and vegetable oils, but the official methods are time-consuming and demand large amounts of reagents and solvents. The present work describes a novel procedure for determination of iodine value based on the discoloration of a triiodide aqueous solution due t
J. Braz. Chem. Soc.. Publicado em: 2018-08
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42. A sensitive bioanalytical method development and validation of cabozantinib in human plasma by LC-ESI-MS/MS
ABSTRACT A simple, sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the quantification of cabozantinib (CZ) in human plasma using cabozantinib-d4 (CZD4) as an internal standard (IS). Chromatographic separation was performed on Xbridge C18, 50 x 4.6 mm, 5 mm column with an isocratic mobile phase compose
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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43. Preparation and Ablation Performance of Lightweight Phenolic Composite Material under Oxyacetylene Torch Environment
ABSTRACT The present study investigates the influence of fiber content on thermal properties of short silica fiber (SSF) reinforced modified resole resin (MRR) composites. For this purpose, different SSF loading composites were prepared: 40, 55, and 65 wt.%. The ablation resistance related to mass loss parameters was quantified by testing under an oxyacetyle
J. Aerosp. Technol. Manag.. Publicado em: 21/06/2018
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44. Long-term microwaving of denture base materials: effects on dimensional, color and translucency stability
Abstract While the combined effect of microwave irradiation with cleansing solutions on denture base materials has been investigated, the effects of only using microwave irradiation and, more importantly, in a long-term basis, was not studied yet. Objective The purpose of this study was to evaluate the effect of a long-term repeated microwaving on the dime
J. Appl. Oral Sci.. Publicado em: 18/06/2018
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45. Direct Numerical Simulation Code Validation for Compressible Shear Flows Using Linear Stability Theory
ABSTRACT: In order to simulate compressible shear flow stability and aeroacoustic problems, a numerical code must be able to capture how a baseflow behaves when submitted to small disturbances. If the disturbances are amplified, the flow is unstable. The linear stability theory (LST) provides a framework to obtain information about the growth rate in relatio
J. Aerosp. Technol. Manag.. Publicado em: 07/05/2018
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46. Antioxidant effect of the guava byproduct in the diet of broilers in the starter phase
ABSTRACT This work aimed to investigate the antioxidant capacity of the guava agroindustrial waste as a functional additive in broiler feed to improve the performance and meat quality of boilers. The experiment was conducted in a completely randomized design, consisting of four treatments and six replicates with 12 birds. Treatments included different levels
R. Bras. Zootec.. Publicado em: 23/04/2018
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47. Development and validation of stability indicating liquid chromatographic (RP-HPLC) method for estimation of ubidecarenone in bulk drug and formulations using quality by design (QBD) approach
ABSTRACT A novel, accurate, precise and economical stability indicating Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) method, was developed and validated for the quantitative determination of ubidecarenone (UDC) in bulk drug, UDC marketed formulation and UDC loaded cubosomes (CBMs) nanocarriers through Response surface methodology (RSM) desi
Braz. J. Pharm. Sci.. Publicado em: 05/03/2018
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48. A Novel Sensitive Bulk Optode Based on 5-Br Salophen as an Ionophore for Determination of Zinc Ion in Real Samples
An optical sensing film was fabricated for sensitive determination of zinc ion in aqueous solutions. The optical sensor was prepared by synthesized ionophore, 5-Br salophen, dioctyl sebacate (DOS) as a plasticizer, sodium tetraphenyl borate (NaTPB) as a lipophilic anionic additive in a poly(vinyl chloride) membrane. The optode response is based on the cation
J. Braz. Chem. Soc.. Publicado em: 2018-03