Leucine Supplementation
Mostrando 13-24 de 27 artigos, teses e dissertações.
-
13. Parametros corporais e bioquimicos de ratas gravidas portadoras do carcinossarcoma de Walker 256 submetidas a suplementação de leucina
O desenvolvimento de câncer dá-se de forma mais agressiva e severa em pacientes jovens. Porcentagem pequena, porém significativa, de pacientes acometidos pelo crescimento de neoplasia maligna concomitante à gravidez sofrem da mesma agressividade desta doença, com um agravante pois se trata de dois pacientes: mãe e feto. A mãe sofre alterações fisiol
Publicado em: 2001
-
14. Produção e caracterização de hidrolisado pancreatico de isolado proteico de soja para nutrição clinica
This work dealt with the pancreatic hydrolysis of soy protein isolates (SPI) for the production of a low molecular weight hydrolysis, as well as the biochemical and nutritional characterization of the product. The selected process was a discontinuous one at 37° C in deionized water and without pH adjustment in order to minimize concentration of inorganic io
Publicado em: 1992
-
15. Attenuation of and Protection Induced by a Leucine Auxotroph of Mycobacterium tuberculosis
Attenuated mutants of Mycobacterium tuberculosis represent potential vaccine candidates for the prevention of tuberculosis. It is known that auxotrophs of a variety of bacteria are attenuated in vivo and yet provide protection against challenge with wild-type organisms. A leucine auxotroph of M. tuberculosis was created by allelic exchange, replacing wild-ty
American Society for Microbiology.
-
16. Microbial Production of Tenuazonic Acid Analogues
The fungus Alternaria tenuis normally produces tenuazonic acid (3-acetyl-5-secbutyltetramic acid). On supplementation of the culture substrate with l-valine and l-leucine, the organism formed two new tetramic acids, 3-acetyl-5-isopropyltetramic acid and 3-acetyl-5-isobutyltetramic acid, respectively. l-Phenylalanine was not utilized by the organism as a tetr
-
17. Reduced leu operon expression in a miaA mutant of Salmonella typhimurium.
Salmonella typhimurium miaA mutants lacking the tRNA base modification cis-2-methylthioribosylzeatin (ms2io6A) were examined and found to be sensitive to a variety of chemical oxidants and unable to grow aerobically at 42 degrees C in a defined medium. Leucine supplementation suppressed both of these phenotypes, suggesting that leucine synthesis was defectiv
-
18. Stimulation of yeast ascospore germination and outgrowth by S-adenosylmethionine.
The supplementation of S-adenosylmethionine (SAM) to germination medium stimulated the accumulation of [14C]uracil from the medium into germinating cells, as well as its incorporation into ribonucleic acid during germination and outgrowth of ascospores of Saccharomyces cerevisiae. In addition to uracil, the accumulation of leucine, cytosine, serine, and meth
-
19. 25-hydroxycholecalciferol stimulation of muscle metabolism.
Intact diaphragms from vitamin D-deficient rats were incubated in vitro with [3H]leucine. Oral administration of 10 mug (400 U) of cholecalciferol 7 h before incubation increased leucine incorporation into diaphragm muscle protein by 136% (P less than 0.001) of the preparation from untreated animals. Nephrectomy did not obliterate this response. ATP content
-
20. Effect of Alanine, Leucine, and Fructose on Lysyl-Transfer Ribonucleic Acid Ligase Activity in a Mutant of Escherichia coli K-12
A mutant of Escherichia coli K-12 was examined which has growth medium-dependent lysyl-transfer ribonucleic acid (tRNA) ligase activity. In minimal medium or 0.5% yeast extract, the activity of the enzyme in the mutant strain was 5 to 10% of wild type. However, when the mutant was grown in a highly enriched medium, such as AC broth (Difco), the activity of t
-
21. Prolonged maternal amino acid infusion in late-gestation pregnant sheep increases fetal amino acid oxidation
Protein supplementation during human pregnancy does not improve fetal growth and may increase small-for-gestational-age birth rates and mortality. To define possible mechanisms, sheep with twin pregnancies were infused with amino acids (AA group, n = 7) or saline (C group, n = 4) for 4 days during late gestation. In the AA group, fetal plasma leucine, isoleu
American Physiological Society.
-
22. Thiostrepton, an Inhibitor of 50S Ribosome Subunit Function
Thiostrepton inhibits 14C-leucine incorporation by intact cells of Bacillus megaterium as well as 14C-phenylalanine incorporation by a poly U-directed extract of Escherichia coli. Extracts of E. coli which are pretreated by incubation with thiostrepton cannot be reactivated by dialysis to more than 5% of their former activity. The 50S ribosome subunit appear
-
23. Identification of 3-methylglutarylcarnitine. A new diagnostic metabolite of 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency.
Deficiency of 3-hydroxy-3-methylglutaryl-coenzyme A (CoA) lyase affects the metabolism of leucine as well as ketogenesis. This disorder is one of an increasing list of inborn errors of metabolism that presents clinically like Reye's Syndrome or nonketotic hypoglycemia. Four patients with proven 3-hydroxy-3-methylglutaryl-CoA lyase deficiency were shown to ex
-
24. A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins.
A second cluster of genes encoding the E1 alpha, E1 beta, and E2 subunits of branched-chain alpha-keto acid dehydrogenase (BCDH), bkdFGH, has been cloned and characterized from Streptomyces avermitilis, the soil microorganism which produces anthelmintic avermectins. Open reading frame 1 (ORF1) (bkdF, encoding E1 alpha), would encode a polypeptide of 44,394 D