Langerhans Cells
Mostrando 25-36 de 244 artigos, teses e dissertações.
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25. Histiocitose das Células de Langerhans na criança:: Revisão dos achados clínicos, anátomo-patológicos e imuno-histoquímicos dos casos diagnosticados no Hospital das Clínicas da UFMG 1988 a 2008
Objectives: To review clinical, histopathological and immunohistochemical findings of children and adolescents with previous diagnosis of Langerhans cell histiocytosis (LCH), in order to establish the definitive diagnosis through CD1a antigen staining. To compare the disease outcome according to age, sex, stage of the disease, treatment response and level of
Publicado em: 2009
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26. A expressão e atividade da NAD(P)H oxidase em ilhotas pancreáticas de ratos tratados com dieta hiperlipídica. / NAD(P)H oxidase expression and activity in pancreatic islets from rats treated with high fat diet.
Feeding animals with high fat diet containing lard causes obesity, insulin resistance and dysfunction of pancreatic beta cells. High fat diet induces oxidative stress and modulates NAD(P)H oxidase expression and activity in many tissues. This enzyme may be involved in many pathophysiological processes. The objective of this study was to evaluate the action o
Publicado em: 2009
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27. Estudo de células dendríticas, expressão das citocinas TNF-alfa, IFN-gama e IL-10 e da molécula de adesão E-caderina em lesões vulvares induzidas pelo papilomavírus humano / Study of dendritic cells, cytokines TNF-alpha, IFN-gamma and IL-10 and the adhesion molecule E-cadherin in vulvar lesions induced by human papillomavirus
INTRODUCTION: The human papillomavirus (HPV) is the most frequent agent in sexually transmitted diseases and is responsible for almost 40% of vulvovaginal cancer. We studied the immune response in vulvar lesions, considering the CD1a+, FXIIIa+ and S-100+ dendritic cells, TNF-, IFN- and IL-10 cytokines and the adhesion molecule E-cadherin. METHODS: We used 49
Publicado em: 2009
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28. Obtention of human pancreatic islets for transplantation through an increase in cell mass and an immunoisolation with biocompatible microcapsules / Ilhotas pancreáticas humanas viáveis para o transplante através do aumento da massa de células e do imunoisolamento com microcápsulas biocompatíveis
Islet transplantation has been proposed as a promising therapeutic strategy for the cure of type 1 diabetes mellitus (DM), however, its application to all diabetic patients is still not possible due to the limited source of islets or β cells and to the need of an immunosuppressive treatment of the recipient to avoid graft rejection. The use of immunosup
Publicado em: 2009
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29. Modulação do mecanismo de sedreção de insulina em ilhotas pancreaticas de ratos submetidos a restrição protetica e suplementados com taurina / Insulin secretion mechanisms in pancreatic islets of protein-restricted rats supplemented with taurine
Malnutrition still is a public health issue, especially in developing countries. Many studies correlate malnourishment during early life and the development of cardiovascular disease and type 2 Diabetes Mellitus on latter stages. Animal models of malnutrition reveal impaired insulin secretion stimulated by glucose and other insulinotropic agents as well as l
Publicado em: 2009
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30. Ciliary Neurotrophic Factor (CNTF) effects over pancreatic islets function and survival / Efeitos do Ciliary Neurotrophic Factor (CNTF) sobre a função e sobrevivencia de ilhotas pancreaticas
Introduction: CNTF belongs to the IL-6 cytokine family and as such, it signals through gp130 receptor complex, activating many pathways depending on the cell-type, mainly STAT3, MAPK and PI3K. Its effects include increased neuron differentiation and/or survival, and are differentially expressed throughout the animal life. Meanwhile, pancreatic islets are ric
Publicado em: 2009
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31. Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
The aim of the present study was to compare quantitatively the distribution of dendritic cell subpopulations in chronic periodontitis and gingivitis. Fourteen biopsies from patients with chronic periodontitis and fifteen from patients with gingivitis were studied. An immunoperoxidase technique was used to quantify the number of Langerhans' cells (CD1a) and i
Brazilian Oral Research. Publicado em: 2008-09
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32. Dendritic cells, inducible nitric oxide synthase and citokines expression in pityriasis lichenoides skin lesions / Células dendríticas, expressão da forma induzida da óxido nítrico sintase e padrão de citocinas nas lesões de pitiríase liquenóide
BACKGROUND: Pityriasis lichenoides (PL) is a cutaneous disease of unknown etiology which has been regarded as an immunologically mediated reaction. Recently, it was reclassified in the group of Cutaneous Lymphoid T cell Dyscrasia. There are few reports addressing mainly T cell subsets in PL tissue reaction. METHODS: Skin biopsies taken from 34 patients with
Publicado em: 2008
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33. Comparison of the effect of ganglioside GM1 and the Nerve Growth Factor (NGF) on the expression of receiver of high affinity for NGF, TrkA and insulin in isolated pancreatic islets of NOD mice (non obese diabetic) / Comparação dos efeitos do gangliosideo GM1 e do fator de crescimento neural (NGF) sobre a expressão de receptor de alta afinidade para NGF, TrkA e insulina em ilhotas pancreaticas isoladas de camundongos NOD (diabetico não obeso)
The non-obese diabetic mice (NOD) lineage is characterized by developing type 1 diabetes mellitus (DM-1) naturally, bearing a similarity to DM-1 in human beings. The spontaneous manifestation of diabetes is characterized by gradual infiltration in pancreatic islets by mononuclear cells lymphocytes T (CD4+ and CD8+) and destruction of the ß-cells producers o
Publicado em: 2008
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34. Avaliação dos efeitos de diferentes concentrações de dexametasona sobre parametros fisiologicos de ilhotas pancreaticas / Evaluation of the effects of different dexamethasone concentyrations on physiological parameters in pancreatic islets
A resistência à insulina (RI) é uma condição que exige maiores níveis de insulina circulante e que normalmente são providenciados pelo aumento da função e população de células ß. A RI pode ser observada a partir de diversos modelos experimentais em roedores tais como os modelos transgênicos, de gravidez, submetidos às dietas hiperlipídicas e
Publicado em: 2008
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35. Avaliação da resposta tecidual "in situ" do fenótipo, da expressão de HHV-8/LANA e de citocinas em lesões cutâneas de sarcoma de Kaposi clássico e sarcoma de Kaposi associado à AIDS na era pré e pós-terapia anti-retroviral combinada / Evaluation of tissue response "in situ" of the phenotype, expression of HHV-8/LANA and cytokines in cutaneous lesions of classic Kaposi sarcoma and AIDS associated Kaposi sarcoma in the pre-and post- highly active antiretroviral therapy era
Kaposis sarcoma (KS) is a vascular-originated tumor associated to human herpesvirus 8 (HHV-8). The incidence of AIDS-KS has decreased after the advent of highly active antiretroviral therapy (HAART), without studies regarding cutaneous inflammatory response and HHV-8 expression in pre- and post-HAART era. We used immunohistochemistry to characterize and to q
Publicado em: 2008
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36. Secreção e sensibilidade periférica à insulina e hormônios contra-regulatórios do morcego hematófago Desmodus rotundus
In general, mammals fed on high protein diets (HP) are more resistant to starvation. However, the hematophagous bat Desmodus rotundus, althougth having a HP diet (blood), is markedly susceptive to the food deprivation, presenting severe hypoglycemia after 24h of starvation. Besides, this species has small stores of hepatic glycogen and adipose tissue lipid,
Publicado em: 2008