L1 Observable
Mostrando 25-36 de 44 artigos, teses e dissertações.
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25. Chimeric L-type Ca2+ channels expressed in Xenopus laevis oocytes reveal role of repeats III and IV in activation gating.
1. Chimeric alpha 1 subunits consisting of repeat I and II from the rabbit cardiac (alpha 1C-a) and repeat III and IV from the carp skeletal muscle Ca2+ channel (alpha 1S) were constructed and expressed in Xenopus laevis oocytes without co-expressing other channel subunits. Ba2+-current kinetics of five chimeric channel constructs were studied in Xenopus ooc
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26. Plant growth in elevated CO2 alters mitochondrial number and chloroplast fine structure
With increasing interest in the effects of elevated atmospheric CO2 on plant growth and the global carbon balance, there is a need for greater understanding of how plants respond to variations in atmospheric partial pressure of CO2. Our research shows that elevated CO2 produces significant fine structural changes in major cellular organelles that appear
The National Academy of Sciences.
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27. Nuclear magnetic resonance study of the conformation and dynamics of beta-casein at the oil/water interface in emulsions.
A (13)C and (31)P nuclear magnetic resonance (NMR) study has been carried out on beta-casein adsorbed at the interface of a tetradecane/water emulsion. (13)C NMR spectra show signals from the carbonyl, carboxyl, aromatic, and C alpha carbons in beta-casein, well resolved from solvent resonances. Only a small fraction of all carbon atoms in beta-casein contri
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28. Do Phytotropins Inhibit Auxin Efflux by Impairing Vesicle Traffic?1
Phytotropins such as 1-N-naphthylphthalamic acid (NPA) strongly inhibit auxin efflux, but the mechanism of this inhibition remains unknown. Auxin efflux is also strongly decreased by the vesicle trafficking inhibitor brefeldin A (BFA). Using suspension-cultured interphase cells of the BY-2 tobacco (Nicotiana tabacum L. cv Bright-Yellow 2) cell line, we compa
American Society of Plant Biologists.
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29. Infectious diarrhea of infant rats produced by a rotavirus-like agent.
During the investigation of an outbreak of diarrhea in suckling rats, a virus morphologically identical to but antigenically distinct from rotaviruses was identified. The disease was characterized clinically by erythema and cracking and bleeding of the perianal skin associated with the excretion of poorly formed fecal pellets, liquid, and gas. Light microsco
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30. Clinical responses with active specific intralymphatic immunotherapy for cancer--a phase I-II trial.
We evaluated the method of active specific intralymphatic immunization to treat cancer in 32 patients with various tumor types as part of a broad-based phase I-II evaluation and describe the results of 3 sequential series. In series 1, the patients (n = 13) received 2 or more injections of autologous, cryopreserved, irradiated tumor cells directly into the l
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31. Septal deafferentation increases hippocampal adrenergic receptors: correlation with sympathetic axon sprouting.
Denervation of the hippocampal formation in adult rats through lesion of the medial septum and diagonal band or by transection of the fimbria/fornix elicits an increase in the number of putative alpha-adrenergic receptor binding sites labeled by the antagonist ligand [3H]WB4101 [2-(2,6-dimethoxyphenoxyethyl)-aminomethyl-1,4-benzodioxane]. This increase in [3
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32. Heterogeneous Distribution of Microbial Activity in Methanogenic Aggregates: pH and Glucose Microprofiles
Methanogenic aggregates, harvested from an upflow anaerobic sludge blanket reactor treating potato starch wastewater, were acclimatized to either glucose or a mixture of sugars and organic nitrogen compounds (i.e., diluted molasses). Both types of granules exhibited internal pH and substrate concentration gradients in mineral medium (pH 7.0, 30°C) as was me
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33. The Ribavirin Analog ICN 17261 Demonstrates Reduced Toxicity and Antiviral Effects with Retention of both Immunomodulatory Activity and Reduction of Hepatitis-Induced Serum Alanine Aminotransferase Levels
The demonstrated utility of the nucleoside analog ribavirin in the treatment of certain viral diseases can be ascribed to its multiple distinct properties. These properties may vary in relative importance in differing viral disease conditions and include the direct inhibition of viral replication, the promotion of T-cell-mediated immune responses via an enha
American Society for Microbiology.
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34. Genetic Regulation of Development in Sorghum bicolar1: I. Role of the Maturity Genes
The photoperiodic behavior and other developmental and morphological differences of 11 maturity genotypes (as identified by JR Quinby 1967, Adv Agron 19: 267-305) of the milo group of Sorghum bicolor (L.) Moench were studied under 8, 10, 12, and 14 hour photoperiods. Sorghum is a quantitative short day plant. The genotypes studied differ in genes which modif
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35. Lamellar-to-hexagonalII phase transitions in the plasma membrane of isolated protoplasts after freeze-induced dehydration.
In protoplasts isolated from nonacclimated rye leaves (Secale cereale L. cultivar Puma), cooling to -- 10 degrees C at a rate of 1 degrees C/min results in extensive freeze-induced dehydration (osmotic contraction), and injury is manifested as the loss of osmotic responsiveness during warming. Under these conditions, several changes were observed in the free
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36. The order of processing events in mouse mammary tumor virus envelope protein maturation: implications for the location of the glucocorticoid-regulated step.
Treatment of the W7MG1 mouse T lymphoma cell line with glucocorticoid stimulates directly or indirectly two observable steps in the processing of mouse mammary tumor virus (MMTV) envelope glycoprotein precursor Pr74: cleavage of Pr74 to yield the mature glycoprotein products gp52 and gp33, and processing of the N-linked oligosaccharides to endoglycosidase H