L Type Calcium Current
Mostrando 1-12 de 168 artigos, teses e dissertações.
-
1. Screening, diagnosis and management of hypothyroidism in pregnancy: Number 10 – October 2022
Key points Pregnancy places a metabolic overload on the maternal thyroid, especially in the first trimester, mainly because of the demand imposed by the conceptus. The fetal thyroid becomes functionally mature only around pregnancy week 20. Until then, the fetus depends on the transfer of maternal thyroid hormones (THs). Thyroid hormones are essential for
Revista Brasileira de Ginecologia e Obstetrícia. Publicado em: 2022
-
2. Nitric oxide modulates ATP-evoked currents in mouse Leydig cells
Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and intracellular calcium storages recruited by a calcium-induced calcium release mechanism. On the other hand
Braz J Med Biol Res. Publicado em: 15/03/2018
-
3. EFFECT OF AQUEOUS FRACTION OF LEAVES DE COSTUS SPIRALIS (JACQ.) ROSCOE CONTRACTILE FUNCTION ON HEART MAMMALS. / EFEITO DA FRAÇÃO AQUOSA DAS FOLHAS DE COSTUS SPIRALIS (JACQ.) ROSCOE SOBRE A FUNÇÃO CONTRÁTIL DO CORAÇÃO DE MAMÍFEROS.
Teas and infusions from C. spiralis leaf have largely been used by folk medicine as diuretic, hypotensor, cytotoxic, immunomodulator, antilithiasic, antidiarrheic, antispasmodic, antiurolitic, antimicrobian, antifungic, antioxidant, antileishmania activity, antiinflamatory, and antiedematogenic activity. In spite of these biological effects attributed to the
Publicado em: 2011
-
4. A computer simulation study of motoneuron models with active dendrites in response to synaptic inputs. / Estudo por simulação computacional de modelos de motoneurônios com dendrito ativo em resposta a entradas sinápticas.
Mathematical models of motoneurons have been developed as an aid to the understanding of phenomena involving the neuromuscular system, but most of these models have been based on the hypothesis of a passive dendritic tree. This holds for anesthetized animals but not necessarily during normal motor behavior of the intact animal. Experiments with decerebrate a
Publicado em: 2010
-
5. Disfunção cardíaca em animal nocaute para o receptor do tipo 2 para bradicinina
The Kinins are important peptides concerning control of cardiovascular function. Their action mechanism depend on the activation of two distinct receptor, type 1 and 2 bradykinin receptor (B1R and B2R). They both are coupled to G protein, which are responsible to activate different intracellular pathways, involved in different cellular process. Their role in
Publicado em: 2009
-
6. Investigação do efeito vasorelaxante e caracterização eletrofisiológica dos alcalóides curina e reticulina
It was been demonstrated that curine and reticuline, induced a vasodilator effect in the rat small mesenteric arteries through inhibition of voltage-gated Ca2+ channels (VGCC). These compounds, curine and reticuline were isolated from the root barks of Chondrondendron platyphyllum and Ocotea duckei Vattimo, respectively, therefore the aim of this work was to
Publicado em: 2009
-
7. Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure
Infarct-induced heart failure is usually associated with cardiac hypertrophy and decreased ß-adrenergic responsiveness. However, conflicting results have been reported concerning the density of L-type calcium current (I Ca(L)), and the mechanisms underlying the decreased ß-adrenergic inotropic response. We determined I Ca(L) density, cytoplasmic calcium ([
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-05
-
8. Desaceleração de um feixe atomico de Ca com laser de diodo de frequencia dobrada
This work presents the results of a calcium atomic bean deceleration using a frequency-doubled diode laser. The diode laser produces single-mode output power of 150 mW at a maximum injection current of 160 mA. The nonlinear crystal used for second harmonic generation is the KnbO3 by noncritical and type I phase matching process. For l =845 nm the phase match
Publicado em: 1998
-
9. Calcium current modulation in frog sympathetic neurones: L-current is relatively insensitive to neurotransmitters.
1. Neurotransmitters (noradrenaline, NA; chicken II luteinizing hormone-releasing hormone, LHRH) and activators of G proteins (GTP-gamma-S and AlF3) partially inhibit calcium current in bullfrog sympathetic neruones. Activation of the remaining current is slowed and shifted to more positive voltages. 2. The N-type calcium current appears to be the type modul
-
10. Modulation of L-type calcium channels by sodium ions.
It is universally believed that the removal of external sodium ions is without effect on calcium current. We now report that in enzymatically isolated guinea pig ventricular cells, the replacement of external sodium ions with certain other cations causes a 3- to 6-fold increase in peak L-type calcium current. The increase in current is reversibly blocked by
-
11. Gamma-aminobutyrate type B receptor modulation of L-type calcium channel current at bipolar cell terminals in the retina of the tiger salamander.
Bipolar-cell axon terminals receive direct synaptic input from amacrine-cell processes, suggesting a possible pathway for modulation of transmitter release. In retinal slices, bath-applied baclofen, a gamma-aminobutyrate type B (GABAB) receptor agonist, reduced a patch-clamp-recorded L-type calcium channel current in a population of bipolar cells with axon t
-
12. Single L-type calcium channel conductance with physiological levels of calcium in chick ciliary ganglion neurons.
1. Single L-type calcium channels in chick ciliary ganglion neurons were studied at high current resolution in cell-attached patch recordings using quartz-glass micropipettes. 2. A single open-channel current amplitude was observed when Ba2+ was the charge carrier with a conductance of 26 pS at 110 mM barium. However, with 110 mM calcium two current fluctuat