Krebs Cycle Intermediates
Mostrando 1-12 de 33 artigos, teses e dissertações.
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1. CARACTERIZAÇÃO DA ATIVIDADE PRÓ-OXIDANTE DE DIFERENTES AGENTES E ESTUDO DO POTENCIAL ANTIOXIDANTE DE INTERMEDIÁRIOS DO CICLO DE KREBS SOBRE ALTERAÇÕES OXIDATIVAS INDUZIDAS IN VITRO / EFFECT OF KREBS CYCLE INTERMEDIATES ON OXIDATIVE CHANGES INDUCED BY DIFFERENT OXIDANT AGENTS
Dados prévios da literatura têm mostrado que alguns intermediários do ciclo de Krebs podem agir como antioxidantes em diversos modelos, tanto in vitro, quanto in vivo. Porém, o(s) mecanismo(s) através dos qual(is) esses intermediários exercem suas atividades antioxidantes não são completamente entendidas. Considerando a escassez de dados na literatur
Publicado em: 2008
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2. EFEITO DE INTERMEDIÁRIOS DO CICLO DE KREBS SOBRE ALTERAÇÕES OXIDATIVAS INDUZIDAS POR DIFERENTES AGENTES OXIDANTES / EFFECT OF KREBS CYCLE INTERMEDIATES ON OXIDATIVE CHANGES INDUCED BY DIFFERENT OXIDANT AGENTS
Recent data from the literature have suggested that some Krebs cycle intermediates could act as potent antioxidant agents, both in vitro and in vivo, against a variety of pro-oxidant agents. However, the mechanism(s) involved in the antioxidant effect of Krebs cycle intermediates are not fully understood. Additionally, there are scarce data in the literature
Publicado em: 2006
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3. Glycogen depletion and acute branched-chain aminoacids supplementation on submaximal exercise in trained rats : implications on anaplerotic reactions / Depleção de glicogenio e suplementação aguda de aminoacidos de cadeia ramificada em ratos treinados : implicações sobre as reações anapleroticas
During submaximal exercise, muscle glycogen utilization is important. Branched-chain AminoAcids supplementation has been utilized during the past years to provide energy for muscles in this condition, through their carbon skeletons, which might generate tricarboxilic acids cycle´s intermediates (TCAI). However, this hypothesis remains controversial. On the
Publicado em: 2005
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4. Biosynthesis and metabolism of steroid hormones by human adrenal carcinomas
Over a 15-year period, our university-based laboratory obtained 125 adrenal tumors, of which 15 (12%) were adrenal cortical carcinomas. Of these, 6 (40% of the carcinomas) occurred in patients with clear clinical manifestations of steroid hormone excess. Adrenal cortical carcinoma cells derived from the surgically resected tumors in 4 of these patients were
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-10
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5. Interactions between lithium and renal transport of Krebs cycle intermediates.
The effect of lithium on the renal transport of Krebs cycle intermediates was studied in brush border membrane vesicles isolated from the rabbit renal cortex. The di- and tricarboxylic acids are avidly transported across renal brush border membranes by a sodium cotransport system. Lithium acted as a potent, specific, competitive inhibitor (Ki = 1.2 mM) of su
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6. Evidence for regulation of gluconeogenesis by the fructose phosphotransferase system in Salmonella typhimurium.
A genetic locus designated fruR, previously mapped to min 3 on the Salmonella typhimurium chromosome, gave rise to constitutive expression of the fructose (fru) regulon and pleiotropically prevented growth on all Krebs cycle intermediates. Regulatory effects of fruR were independent of cyclic AMP and its receptor protein and did not prevent uptake of Krebs c
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7. Metabolism of d-Fructose by Arthrobacter pyridinolis
Previous studies showed that Arthrobacter pyridinolis can transport and utilize d-glucose only after prior growth on certain Krebs cycle intermediates. In contrast, we found that d-fructose was taken up and metabolized by A. pyridinolis without special prior conditions of growth. d-Fructose was first converted to d-fructose-1-phosphate by a phosphoenolpyruva
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8. EFFECT OF STREPTOLYSIN O ON THE UTILIZATION OF SOME KREBS CYCLE INTERMEDIATES BY AEROBACTER AEROGENES
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9. Carbohydrate Metabolism in Leukocytes VII. Metabolism of Glucose, Acetate, and Propionate by Human Plasma Cells
Plasma cells obtained from the peripheral blood of a patient with multiple myeloma was incubated in serum and Krebs-Ringer bicarbonate buffer with 14C-labeled glucose, acetate, and propionate. Glucose utilization by these cells amounted to 0.5 μmole per hr per 108 cells and was mainly via the Embden-Meyerhof pathway, and only 6% or less traversed the hexose
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10. EFFECT OF SALMONELLA GALLINARUM ON CERTAIN KREBS CYCLE INTERMEDIATES OF DOMESTIC FOWL
Freeman, B. M. (Houghton Poultry Research Station, Huntingdon, England), and L. G. Chubb. Effect of Salmonella gallinarum on certain Krebs cycle intermediates of domestic fowl. J. Bacteriol. 88:93–95. 1964.—In chickens infected with Salmonella gallinarum, the citric acid content of the blood rose but that of the liver fell significantly. The former may b
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11. STUDIES ON THE METABOLISM OF MYCOBACTERIUM TUBERCULOSIS VI. : The Effect of Krebs' Tricarboxylic Acid Cycle Intermediates and Precursors on the Growth and Respiration of Mycobacterium Tuberculosis1
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12. Itaconate biosynthesis in Aspergillus terreus.
Itaconate biosynthesis was studied in intact cells of high-yield (RC4') and low-yield (CM85J) strains of the fungus Aspergillus terreus by methods (tracers, nuclear magnetic resonance spectroscopy, and mass spectroscopy) that did not interfere with metabolism. Itaconate formation in RC4' required de novo protein biosynthesis. Krebs cycle intermediates increa