Krebes
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. MECANISMO DE AÇÃO DO VASORRELAXAMENTO INDUZIDO PELO ÓLEO ESSENCIAL DO Croton argyrophylloides EM AORTA DE RATO / MECHANISM OF ACTION OF VASORRELAXAMENTO INDUCED BY THE ESSENTIAL OIL Croton argyrophylloides IN RAT AORTA
O Croton argyrophylloides é uma planta nativa do Nordeste brasileiro aonde é popularmente chamada de marmemeiro prateado devido à coloração de suas folhas. O óleo essencial do Croton argyrophylloides (OECa) apresentou dois interessantes efeitos farmacológicos: ele foi capaz de relaxar o músculo liso vascular e possui uma elevada DL50. O objetivo prin
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/03/2011
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2. Metabolismo do nitrogênio no sistema radicular de leguminosas em condição de hipoxia / Nitrogen metabolism in roots system of legumes in under hypoxia
O papel do metabolismo do nitrogênio na sobrevivência de plantas noduladas de Lotus japonicus foi investigado durante períodos de alagamento. O acúmulo de alanina revelou ser um dos pontos críticos durante a hipoxia, uma vez que esse foi o único aminoácido cuja biossíntese não foi inibida pela deficiência de nitrogênio observada em plantas mutante
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/05/2010
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3. Phosphorylation of Mycoplasma pneumoniae cytadherence-accessory proteins in cell extracts.
A cell-free system was used to characterize the phosphorylation of Mycoplasma pneumoniae proteins HMW1 and HMW2, which are involved in the adherence of this organism to human tracheal epithelium during infection. The pH and cation requirements for phosphorylation of HMW1 and HMW2 were determined, and the effects of glycolytic intermediates, cyclic AMP, and e
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4. The outer membrane protein OprM of Pseudomonas aeruginosa is encoded by oprK of the mexA-mexB-oprK multidrug resistance operon.
An outer membrane protein (OprK) overproduced in a multiply antibiotic-resistant strain of Pseudomonas aeruginosa was previously identified as the product of the third gene of a multidrug resistance operon, mexA-mexB-oprK (K. Poole, K. Krebes, C. McNally, and S. Neshat, J. Bacteriol. 175:7363-7372, 1993). To determine whether this protein was identical to an
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5. Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa.
We have earlier described mexA-mexB-oprK, an operon involved in pyoverdine export in Pseudomonas aeruginosa, and suggested that the products of these genes also contribute to the active efflux of several antibiotics (K. Poole, K. Krebes, C. McNally, and S. Neshat, J. Bacteriol. 175:7363-7372, 1993). Recently the outer membrane component of this efflux system
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6. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa.
Multidrug-resistant derivatives of Pseudomonas aeruginosa PAO1 were obtained after stepwise selection on tetracycline or erythromycin. Two phenotypes were generated. The tetracycline-resistant mutant (TETR) was phenotypically similar to OprM-overexpressing strains. This group displayed cross-resistance to quinolones, chloramphenicol, and all beta-lactams tes
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7. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin.
Most strains of Pseudomonas aeruginosa are significantly more resistant, even in the absence of R plasmids, to many antimicrobial agents, including beta-lactams, tetracycline, chloramphenicol, and fluoroquinolones, than most other gram-negative rods. This broad-range resistance has so far been assumed to be mainly due to the low permeability of the P. aerugi