Kdr Mutation
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Contrasting patterns of insecticide resistance and knockdown resistance (kdr) in Aedes aegypti populations from Jacarezinho (Brazil) after a Dengue Outbreak
ABSTRACT After a dengue outbreak, the knowledge on the extent, distribution and mechanisms of insecticide resistance is essential for successful insecticide-based dengue control interventions. Therefore, we evaluated the potential changes to insecticide resistance in natural Aedes aegypti populations to Organophosphates (OP) and Pyrethroids (PY) after chemic
Rev. Bras. entomol.. Publicado em: 2016-03
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2. Insecticide resistance and genetic variability in natural populations of Aedes (Stegomyia) aegypti (Diptera: Culicidae) from Colombia
Mosquito control prevails as the most efficient method to protect humans from the dengue virus, despite recent efforts to find a vaccine for this disease. We evaluated insecticide resistance and genetic variability in natural populations of Aedes aegypti (Linnaeus, 1762) from Colombia. This is the first Colombian study examining kdr mutations and population
Zoologia (Curitiba). Publicado em: 2015-02
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3. Aedes aegypti on Madeira Island (Portugal): genetic variation of a recently introduced dengue vector
The increasing population of Aedes aegypti mosquitoes on Madeira Island (Portugal) resulted in the first autochthonous dengue outbreak, which occurred in October 2012. Our study establishes the first genetic evaluation based on the mitochondrial DNA (mtDNA) genes [cytochrome oxidase subunit I (COI) and NADH dehydrogenase subunit 4 (ND4)] and knockdown resist
Mem. Inst. Oswaldo Cruz. Publicado em: 2013
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4. Populations of Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae) of municipalities of the State of Ceara: mechanisms of resistance to insecticides organophosphates and pyrethroids and potential natural and synthetic quinones for the management of resistance / Populações de Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae) de municípios do Estado do Ceará: mecanismos de resistência a inseticidas organofosforados e piretróides e potencial de quinonas naturais e sintéticas para manejo da resistência
Populações de Aedes aegypti resistentes ao temefós e à cipermetrina estão presentes em diversos municípios brasileiros, comprometendo o sucesso do programa de controle vetorial vigente. Para a elaboração de planos efetivos de manejo da resistência é indispensável conhecer os mecanismos envolvidos neste processo. Este trabalho buscou identificar os
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2010
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5. Tight genetic linkage between the kdr insecticide resistance trait and a voltage-sensitive sodium channel gene in the house fly.
The kdr insecticide resistance trait in the house fly, Musca domestica, confers resistance to the rapid paralysis (knockdown) and lethal effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and pyrethroids. Flies with the kdr trait exhibit reduced neuronal sensitivity to these compounds, which are known to act at voltage-sensitive sodium channels o
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6. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
Receptor tyrosine kinases Flt-1 and Flk-1/KDR, and their ligand, the vascular endothelial growth factor (VEGF), were shown to be essential for angiogenesis in the mouse embryo by gene targeting. Flk-1/KDR null mutant mice exhibited impaired endothelial and hematopoietic cell development. On the other hand, Flt-1 null mutation resulted in early embryonic deat
The National Academy of Sciences.