Karyotyping
Mostrando 1-12 de 115 artigos, teses e dissertações.
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1. Karyotyping and population genetics in Cold War Mexico: Armendares’s and Lisker’s characterization of child and indigenous populations, 1960s-1980s
Resumo Aborda o trabalho dos geneticistas Salvador Armendares e Rubén Lisker, entre 1960 e 1980, para analisar como se insere nos estudos biológicos humanos do pós-1945, e demonstra como as populações estudadas por eles, a infantil e a indígena, podem ser consideradas laboratórios de produção de conhecimento. O artigo revela como as populações for
Hist. cienc. saude-Manguinhos. Publicado em: 2019-03
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2. Pre-analytical parameters associated with unsuccessful karyotyping in myeloid neoplasm: a study of 421 samples
Cytogenetics is essential in myeloid neoplasms (MN) and pre-analytical variables are important for karyotyping. We assessed the relationship between pre-analytical variables (time from collection to sample processing, material type, sample cellularity, and diagnosis) and failures of karyotyping. Bone marrow (BM, n=352) and peripheral blood (PB, n=69) samples
Braz J Med Biol Res. Publicado em: 14/02/2019
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3. Montagem de cariótipos de peixes assistida por computador
RESUMO A obtenção de cariótipos de peixes desempenha um papel importante em estudos de citotaxonomia e evolução cromossômica das espécies. No entanto, poucos sistemas semi ou completamente automatizados para a obtenção de cariótipo de peixes estão disponíveis. Este trabalho propõe e avalia uma ferramenta baseada em imagens que auxilie a montagem
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2019-02
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4. Is karyotyping still needed in the diagnosis and monitoring of chronic myeloid leukemia?
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-09
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5. Cytomolecular characterization of cultivars and landraces of wheat tolerant and sensitive to aluminum toxicity
ABSTRACT Karyotyping and chromosome complement knowledge are a prerequisite for cytogenetic mapping. The aim of this study was to characterize 1 common wheat cultivar (BH 1146) and 4 durum wheat genotypes (IAC 1003, Langdon, P19 and P33) from the breeding program of the Agronomic Institute of Campinas (IAC), using karyotype analysis together with Chromomycin
Bragantia. Publicado em: 14/08/2017
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6. Validation of QF-PCR for prenatal diagnoses in a Brazilian population
OBJECTIVES: Quantitative fluorescence polymerase chain reaction (QF-PCR) is a rapid and reliable method for screening aneuploidies, but in Brazil, it is not used in public services. We investigated the accuracy of QF-PCR for the prenatal recognition of common aneuploidies and compared these results with cytogenetic results in our laboratory. METHOD: A Chro
Clinics. Publicado em: 2017-07
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7. Persistent Mullerian Duct Syndrome: a rare entity with a rare presentation in need of multidisciplinary management
ABSTRACT Main findings: A typical male looking adolescent with a legal female gender assignment presented with haematuria. Investigations led to the diagnosis of Persistent Mullerian Duct Syndrome. The condition is indeed a rare entity that needs a multidisciplinary team management. Case hypothesis: A case of Persistent Mullerian Duct Syndrome undiagnosed
Int. braz j urol.. Publicado em: 2016-12
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8. Treatment with dasatinib or nilotinib in chronic myeloid leukemia patients who failed to respond to two previously administered tyrosine kinase inhibitors - a single center experience
OBJECTIVE:To evaluate hematological, cytogenetic and molecular responses as well as the overall, progression-free and event-free survivals of chronic myeloid leukemia patients treated with a third tyrosine kinase inhibitor after failing to respond to imatinib and nilotinib/dasatinib.METHODS:Bone marrow karyotyping and real-time quantitative polymerase chain
Clinics. Publicado em: 2015-08
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9. Identifying the similarities and differences between single nucleotide polymorphism array (SNPa) analysis and karyotyping in acute myeloid leukemia and myelodysplastic syndromes
Objective: To standardize the single nucleotide polymorphism array (SNPa) method in acute myeloid leukemia/myelodysplastic syndromes, and to identify the similarities and differ- ences between the results of this method and karyotyping. Methods: Twenty-two patients diagnosed with acute myeloid leukemia and three with myelodysplastic syndromes were studied.
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-02
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10. Diversity of breakpoints of variant Philadelphia chromosomes in chronic myeloid leukemia in Brazilian patients
Background: Chronic myeloid leukemia is a myeloproliferative disorder characterized by the Philadelphia chromosome or t(9;22)(q34.1;q11.2), resulting in the break-point cluster regionAbelson tyrosine kinase fusion gene, which encodes a constitutively active tyrosine kinase protein. The Philadelphia chromosome is detected by karyotyping in around 90% of chro
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-02
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11. Genetic evaluation of mesenchymal stem cells by G-banded karyotyping in a Cell Technology Center
OBJECTIVE: To present the initial results of first three years of implementation of a genetic evaluation test for bone marrow-derived mesenchymal stem cells in a Cell Technology Center.METHODS: A retrospective study was carried out of 21 candidates for cell therapy. After the isolation of bone marrow mononuclear cells by density gradient, mesenchymal stem ce
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-06
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12. Tumor suppressor p53 protein expression: prognostic significance in patients with low-risk myelodysplastic syndrome
BACKGROUND: At the time of diagnosis, more than 50% of patients with myelodysplastic syndrome have a normal karyotype and are classified as having a favorable prognosis. However, these patients often show very variable clinical outcomes. Furthermore, current diagnostic tools lack the ability to look at genetic factors beyond karyotyping in order to determine
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-06