Isosorbide
Mostrando 1-12 de 44 artigos, teses e dissertações.
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1. Thermal and mechanical properties of bio-based plasticizers mixtures on poly (vinyl chloride)
Abstract The use of mixtures of nontoxic and biodegradable plasticizers coming from natural resources is a good way to replace conventional phthalates plasticizers. In this study, two secondary plasticizers of epoxidized sunflower oil (ESO) and epoxidized sunflower oil methyl ester (ESOME) were synthesized and have been used with two commercially available b
Polímeros. Publicado em: 21/09/2017
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2. Formulation and evaluation of transdermal drug-delivery system of isosorbide dinitrate
O objetivo do presente estudo foi desenvolver um sistema de liberação transdérmico do tipo reservatório para o dinitrato de isossorbida (ISDN, abrevitura em Inglês). A formulação transdérmica desenvolvida constou de cinco camadas de baixo para cima, ou seja, um revestimento temporário, uma camada adesiva, uma membrana controladora da taxa de libe
Braz. J. Pharm. Sci.. Publicado em: 2015-06
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3. AVALIAÇÃO DO TRATAMENTO DE FISSURAS ANAIS COM A ISOSSORBIDA TÓPICA A 1%. / ASSESSMENT OF TREATMENT OF ANAL FISSURES ISOSORBIDE WITH A TOPICAL 1%.
Chronic anal fissures are benign, painful, found deep ulcers in the anal canal. Affecting young adults and occur especially by the trauma of hard stools, the sphincter hypertonia and poor vascularization in the anterior and posterior regions of the anus. Its main symptom is pain evacuation. Surgical treatment is most effective with high cure rates, but with
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2010
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4. Estudo comparativo da identificacao de isquemia miocardica pela cineventriculografia contrastada sob o efeito de mononitrato de isossorbitol e pela cintilografia miocardica perfusional em portadores de cardiopatia isquemica / Comparative study for the identification of myocardial ischemia by contrast ventriculography under the effect of isosorbide mononitrate and by perfusional myocardial scintigraphy in patients with ischemic heart disease
Objective – To evaluate and compare the usefulness of cineventriculographies, before and after nitrate use, to technetium-99m sestamibi scintigraphy for the identification of myocardial ischemia. Methods – Twenty-six patients were studied at basal conditions and 5 minutes after intravenous administration of isosorbide mononitrate (0.3mg/kg), to evaluate
Publicado em: 2010
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5. Copolímeros biodegradáveis com potencial uso como biomateriais / Biodegradable Copolymers with Potential use as Biomaterials
With the goal of obtaining a new class of biodegradable copolyesters with improved properties isosorbide succinate (IS) moieties were incorporated into the poly(L-lactide), PLLA, backbone. Three miscible block copolymers and one miscible random copolymer with both hydrophobic character and final degradation temperature higher than PLLA and possessing low ave
Publicado em: 2009
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6. Synthesis and structural characterization of block and random low molecular weight copolymers composed of L-lactic acid and isosorbide succinate moieties
Resíduos de succinato de isosorbídeo foram incorporados na cadeia principal de poli(L-lactídeo) (PLLA) visando a obtenção de uma nova classe de polímeros biodegradáveis com propriedades melhoradas. Este artigo descreve a síntese e caracterização de quatro tipos de copolímeros de baixa massa molar. O copolímero I foi obtido da mistura dos monômer
Journal of the Brazilian Chemical Society. Publicado em: 2009
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7. Produção de polímeros derivados de fontes renováveis via catálise enzimática / Production of polymers derived from renewable sources by enzyme catalysis
A busca por materiais derivados de fontes renováveis e com características como biocompatibilidade e biodegradabilidade tem crescido significativamente nos últimos anos. A utilização de enzimas na polimerização representa um grande passo para a obtenção destes, visto que possibilitam a produção de polímeros evitando a utilização de catalisadore
Publicado em: 2009
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8. Efeito do óxido nítrico sobre fêmures e vértebras lombares de ratos orquiectomizados.
Osteoporosis is attributed to an imbalance between bone formation and resorption, followed by bone mass loss and microarchitectural deterioration, leading to increased bone fragility and fracture risk. Nitric oxide (NO) is a signaling molecule with important regulatory effects on bone cell function. Nitric oxide donor nitroglycerin has been reported to allev
Publicado em: 2007
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9. Quantificação do 5-mononitrato de isossorbida em plasma humano por cromatografia liquida de alta eficiencia acoplada a espectrometro de massa com fotoionização em pressão atmosferica / Quantification of isosorbide 5-moninitrate in human plasma by liquid chromatography tandem mass spectrometry using atmospheric pressure photoionization
O 5-mononitrato de isossorbida (5-MNIS) é um nitrato orgânico comumente usado no tratamento da angina pectoris em razão de suas propriedades vasodilatadoras. No presente estudo, um novo método foi desenvolvido para determinar e quantificar o 5-MNIS no plasma humano por cromatografia líquida acoplada à espectrometria de massa em série (CLAE-EM-EM), usa
Publicado em: 2007
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10. Comparative study of the use of diltiazem as an antispasmodic drug in coronary angiography via the transradial approach
OBJECTIVE: To evaluate the impact of the use, prior to the procedure, of injectable diltiazem to prevent complications. METHODS: Between September 2000 and July 2001, 50 patients underwent transradial coronary angiography and were randomized to receive placebo (GI) or diltiazem (GII) through a catheter inserted into the radial artery. All patients received i
Arquivos Brasileiros de Cardiologia. Publicado em: 2003-07
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11. Gender-related differences in the effects of nitric oxide donors on neuroleptic-induced catalepsy in mice
It has been suggested that nigrostriatal dopaminergic transmission is modulated by nitric oxide (NO). Since there is evidence that gonadal hormones can affect extrapyramidal motor behavior in mammals, we investigated the effects of isosorbide dinitrate (ISD), linsidomine (SIN-1) and S-nitroso-N-acetylpenicillamine (SNAP), three pharmacologically different NO
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02
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12. Haemodynamic effects of oral salbutamol alone and in combination with sublingual isosorbide dinitrate in patients with severe congestive cardiac failure.
To examine possible augmentation of the effects of isosorbide dinitrate by salbutamol, haemodynamic measurements were made in 10 patients with severe chronic congestive cardiac failure who received isosorbide dinitrate 2.5 to 25 mg sublingually and salbutamol 4 to 12 mg orally, alone and in combination. Isosorbide dinitrate reduced mean left ventricular fill