Intraepithelial Lymphocytes
Mostrando 25-36 de 117 artigos, teses e dissertações.
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25. Interleukin 21 up-regulates perforin-mediated cytotoxic activity of human intra-epithelial lymphocytes
Human intra-epithelial lymphocytes (IELs) are predominantly T-cell receptor-αβ+ (TCR-αβ+) CD8+ CD45RO+ memory T cells located between intestinal epithelial cells. They respond to a greater extent to stimulation with interleukin (IL)-15 than to CD3/TCR triggering, suggesting that they react to the cytokine milieu in their local environment rather than to
Blackwell Science Inc.
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26. Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile
γδ T lymphocytes in the intestinal intraepithelial layer (γδ IELs) are thought to contribute to immune competence, but their actual function remains poorly understood. Here we used DNA microarrays to study the gene expression profile of γδ IELs in a Yersinia infection system to better define their roles. To validate this approach, mesenteric lymph node
The National Academy of Sciences.
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27. Coeliac disease with histological features of peptic duodenitis: value of assessment of intraepithelial lymphocytes.
AIMS--To determine if a clinically important polymorphonuclear leucocyte infiltrate and surface gastric epithelial metaplasia occur in the second part of the duodenum in coeliac disease; to evaluate the utility of these morphological criteria in the differential diagnosis of coeliac disease and peptic duodenitis. METHODS--49 mucosal biopsy specimens of the s
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28. Chloride conductance and intracellular chloride accumulation in mouse Peyer's patch enterocytes.
1. Measurements of membrane potential, Cl- conductance and intracellular Cl-, K+, Na+ and H+ activities have been carried out in the follicle-associated epithelium of the mouse Peyer's patch to characterize further the physiological properties of antigen-transporting M cells, enterocytes and intraepithelial lymphocytes. 2. Intraepithelial lymphocytes, identi
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29. Intestinal intraepithelial and splenic natural killer cell responses to eimerian infections in inbred chickens.
Splenic and intestinal natural killer (NK) cell responses were assessed in chickens inoculated with Eimeria parasites. The NK cell activities of both splenic and intestinal intraepithelial lymphocytes (IELs) decreased to a subnormal level during the early phase of eimerian infections but returned to normal or slightly higher than normal levels at about 1 wee
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30. Quantitative analysis of intraepithelial large granular lymphocyte distribution and maternofetal cellular interactions in the synepitheliochorial placenta of the deer.
Intraepithelial lymphocytes are a constant feature of ruminant uterine epithelium in nonpregnant animals. Quantitation in 6 species of deer shows that the proportion of large granular lymphocytes (LGL) in this population increases markedly and continuously from the earliest implantation to the latest (midpregnant) stage examined. The size of individual granu
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31. Genotypic mapping of HPV and assessment of EBV prevalence in endocervical lesions.
AIMS: To examine the prevalence of human papillomavirus (HPV) and Epstein-Barr virus (EBV) in low grade glandular intraepithelial lesions of the cervix, adenocarcinoma with high grade glandular intraepithelial lesions combined, and adenocarcinomas; and to perform a genotyping mapping analysis of endocervical carcinomas to determine the extent of HPV infectio
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32. Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut.
We have studied T-cell receptor (TCR) and alpha/alpha CD8 expression in thymus-independent intraepithelial lymphocytes (TI IELs) from the gut of mice bearing transgenic (TG) TCR alpha beta specific for the male antigen, presented by H-2Db class I major histocompatibility complex (MHC) molecules. In contrast to TCR+ alpha beta cells differentiating in the thy
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33. Bovine Ileal Intraepithelial Lymphocytes Represent Target Cells for Shiga Toxin 1 from Escherichia coli
The discovery that bovine peripheral lymphocytes are sensitive to Stx1 identified a possible mechanism for the persistence of infections with Shiga toxin (Stx)-producing Escherichia coli (STEC) in the bovine reservoir host. If intraepithelial lymphocytes (IEL) are also sensitive to Stx1, the idea that Stx1 affects inflammation in the bovine intestine is high
American Society for Microbiology.
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34. T-cell receptor gamma--delta lymphocytes and Eimeria vermiformis infection.
The role of T-cell receptor gamma--delta T lymphocytes in coccidiosis was examined by determining the course of infection with Eimeria vermiformis in BALB/c mice depleted of gamma--delta lymphocytes by treatment with GL3 monoclonal antibody. The replication of the parasite in primary infections was not greatly, or consistently, affected by this treatment, an
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35. Antibody-dependent and spontaneous cell-mediated cytotoxicity against transmissible gastroenteritis virus infected cells by lymphocytes from sows, fetuses and neonatal piglets.
The purpose of this study was to investigate the ontogeny in the pig of effector lymphocytes mediating antibody-dependent and spontaneous cell-mediated cytotoxicity against target cells infected with transmissible gastroenteritis virus. The same activities were also studied in sows in late pregnancy and early lactation. Peripheral blood lymphocytes and intra
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36. Endometrial lymphoid tissue: an immunohistological study.
Lymphoid tissue of the endometrium was analysed by histological, immunohistological, and electron microscopical methods in 10 healthy uteri. A panel of monoclonal antibodies recognising macrophages (OKMI), HLA-DR antigen, B lymphocytes, T lymphocytes and their subsets, and dendritic reticulum cells was used in a two stage indirect immunoperoxidase labelling