Intracellular Calcium Transient
Mostrando 1-12 de 343 artigos, teses e dissertações.
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1. Pharmacological characterization of the calcium influx pathways involved in nitric oxide production by endothelial cells
RESUMO Objetivo: Caracterizar as vias do influxo de cálcio envolvidas no aumento sustentado da concentração intracelular de cálcio na célula endotelial, essencial para a síntese e a liberação de fatores relaxantes. Métodos: Analisamos o efeito de derivados pirazólicos sintetizados recentemente, descritos como inibidores seletivos para canais ORAI
Einstein (São Paulo). Publicado em: 03/06/2019
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2. EFFECT OF AQUEOUS FRACTION OF LEAVES DE COSTUS SPIRALIS (JACQ.) ROSCOE CONTRACTILE FUNCTION ON HEART MAMMALS. / EFEITO DA FRAÇÃO AQUOSA DAS FOLHAS DE COSTUS SPIRALIS (JACQ.) ROSCOE SOBRE A FUNÇÃO CONTRÁTIL DO CORAÇÃO DE MAMÍFEROS.
Teas and infusions from C. spiralis leaf have largely been used by folk medicine as diuretic, hypotensor, cytotoxic, immunomodulator, antilithiasic, antidiarrheic, antispasmodic, antiurolitic, antimicrobian, antifungic, antioxidant, antileishmania activity, antiinflamatory, and antiedematogenic activity. In spite of these biological effects attributed to the
Publicado em: 2011
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3. Disfunção cardíaca em animal nocaute para o receptor do tipo 2 para bradicinina
The Kinins are important peptides concerning control of cardiovascular function. Their action mechanism depend on the activation of two distinct receptor, type 1 and 2 bradykinin receptor (B1R and B2R). They both are coupled to G protein, which are responsible to activate different intracellular pathways, involved in different cellular process. Their role in
Publicado em: 2009
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4. Study of purinergic receptors in glial cells from dorsal root ganglia. / Estudo dos receptores purinérgicos em células gliais do glânglio da raiz dorsal.
Purinergic receptors are expressed and play role in the sinalization between neurons and glia. In dorsal root ganglia the soma of the sensory neurons is surrounded by a layer of satellite glial cells, whose function is unclear. There are evidences that ATP is released by neurons to act on receptors in satellite cells. So far, the nature of the purinergic rec
Publicado em: 2008
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5. Action of ANP on the nongenomic effects of aldosterone on the Na+/H+ exchanger in the S3 segment of proximal tubule of rat: studies in isolated tubules role of cytosolic calcium. / Ação do ANP no efeito não genômico da aldosterona sobre o trocador Na+/H+ no segmento S3 do túbulo proximal de rato - Estudos em túbulos isolados: função do cálcio citosólico.
The effects of aldosterone and ANP(2 min preincubation) on the intracellular pH recovery rate (pHirr) after the acid load induced by NH4Cl and on the [Ca2+]i were investigated in isolated rat S3 segment. The basal pHi was 7.20 + ou - 0.009(n=47/209) and the basal pHirr via the Na+/H+ exchanger was 0.195 + ou - 0.012 pHi/min(n=16/96). Aldosterone(10-12M) caus
Publicado em: 2008
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6. Study of vasorelaxant effect of one pyrone obtained from Aniba panurensis in isolated superior mesenteric artery rat / Estudo do efeito vasorelaxante de uma pirona obtida de Aniba panurensis em artÃria mesentÃrica superior isolada de rato
6 - [(E) â styryl] â pyron â 2 - one (pyrone-198) is a natural styrylpyrone isolated from the ethanolic extract of the green fruits of Aniba panurensis (Lauraceae). The pyrones demonstrate a whole spectrum of bioactivity and have been shown to be antifungal, antibiotic, cytotoxic and phytotoxic. The aim of this study is to investigate the effects of this
Publicado em: 2007
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7. Characterization of [Ca2+]i responses in primary cultures of mouse cardiomyocytes induced by Trypanosoma cruzi trypomastigotes
Trypanosoma cruzi, the protozoan responsible for Chagas disease, employs distinct strategies to invade mammalian host cells. In the present work we investigated the participation of calcium ions on the invasion process using primary cultures of embryonic mice cardiomyocytes which exhibit spontaneous contraction in vitro. Using Fura 2-AM we found that T. cruz
Memórias do Instituto Oswaldo Cruz. Publicado em: 2003-06
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8. A moderate decrease in temperature inhibits the calcium signaling mechanism(s) of the regulatory volume decrease in chick embryo cardiomyocytes
Chick cardiomyocytes, when submitted to hyposmotic swelling, exhibit a partial regulatory volume decrease (RVD). A Ca2+ influx by stretch-activated channels signals a taurine efflux and the RVD at 37°C. We evaluated the cell's performance at room temperature. Cardiomyocytes isolated and cultured from 11-day-old chick embryos were submitted to a hyposmotic s
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-01
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9. Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium.
Experiments were performed in human working myocardium to investigate the relationship of intracellular calcium handling and availability to alterations in the strength of contraction produced by changes in stimulation rate and pattern. Both control and myopathic muscles exhibited potentiation of peak isometric force during the postextrasystolic contraction
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10. Chloride current induced by injection of calcium into Xenopus oocytes.
Membrane currents of Xenopus oocytes were studied with the membrane under voltage clamp. Intracellular injection of the calcium-chelating agent EGTA reduced, or abolished, the transient outward chloride current normally activated by membrane depolarization. Intracellular injection of calcium ions evoked large membrane currents, which inverted direction close
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11. Calcium transients evoked by electrical stimulation of smooth muscle from guinea-pig ileum recorded by the use of Fura-2.
1. Intracellular free calcium levels were recorded in strips of longitudinal smooth muscle from guinea-pig ileum, by the use of the fluorescent calcium indicator Fura-2. 2. The resting intracellular free calcium concentration was estimated to be 210 nM. Many muscle strips showed spontaneous bursts of contractions, accompanied by bursts of calcium transients.
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12. A role for prefrontal calcium-sensitive protein phosphatase and kinase activities in working memory
The prefrontal cortex is involved in the integration and interpretation of information for directing thoughts and planning action. Working memory is defined as the active maintenance of information in mind and is thought to lie at the core of many prefrontal functions. Although dopamine and other neurotransmitters have been implicated, the intracellular even
Cold Spring Harbor Laboratory Press.